ABIN1169336

antibody from antibodies-online

Targeting: DDX58 DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1169336

Provider

antibodies-online

Product name

anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 201-713) antibody

Antibody type

Monoclonal

Antigen

Recombinant human RIG-I (aa 201-713).

Description

Purified from concentrated hybridoma tissue culture supernatant.

Reactivity

Human, Mouse

Host

Mouse

Epitope

AA 201-713

Isotype

IgG

Antibody clone number

Alme-1

Vial size

100 μg

Concentration

1mg/ml

Storage

Stable for at least 1 year after receipt when stored at -20°C.

References

Submitted references

Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS.

Pythoud C, Rothenberger S, Martínez-Sobrido L, de la Torre JC, Kunz S
Journal of virology 2015 Jun;89(12):6240-50

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Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling.

Weber M, Gawanbacht A, Habjan M, Rang A, Borner C, Schmidt AM, Veitinger S, Jacob R, Devignot S, Kochs G, García-Sastre A, Weber F
Cell host & microbe 2013 Mar 13;13(3):336-46

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Phosphorylation-mediated negative regulation of RIG-I antiviral activity.

Gack MU, Nistal-Villán E, Inn KS, García-Sastre A, Jung JU
Journal of virology 2010 Apr;84(7):3220-9

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The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases.

Rebsamen M, Meylan E, Curran J, Tschopp J
Cell death and differentiation 2008 Nov;15(11):1804-11