DDX58

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]

Description

DExD/H-box helicase 58

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

9:p21.1 (32455302 - 32526208)

Ensembl ID

ENSG00000107201  (ver. 99.38)

Orthologs

Mouse Ddx58: ENSMUSG00000040296

UniProt

O95786

neXtProt

NX_O95786

Human splice variants
Mouse splice variants