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DDX58
DExD/H-box helicase 58DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-31715 |
2 references | Monoclonal |
WB
EL
ICC
FC
OA
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| Proteintech Group | 20566-1-AP |
49 references | Polyclonal |
WB
EL
ICC
IP
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| LSBio | LS-C174703 |
Monoclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-76732 |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN4880676 |
Monoclonal |
WB
EL
ICC
FC
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