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- Antigen structure
- References [23]
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- Product number
- 14748-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14748-1-AP, RRID:AB_2170472
- Product name
- PSMD2 antibody
- Antibody type
- Polyclonal
- Description
- PSMD2 antibody (Cat. #14748-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
N-acetylcysteine suppresses proteasome pathway activation and muscular damage induced by microplastics and chromium nanoparticles.
Mechanism insights into the role of Smc5/6 in HBV inhibition.
RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein.
The S273R protein of African swine fever virus antagonizes the canonical NF-κB signaling pathway by IκBα.
Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14(☆).
Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model.
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin.
PSMD2 overexpression as a biomarker for resistance and prognosis in renal cell carcinoma treated with immune checkpoint and tyrosine kinase inhibitors.
The proteasome activator subunit PSME1 promotes HBV replication by inhibiting the degradation of HBV core protein.
Identification of PSMD2 as a promising biomarker for pancreatic cancer patients based on comprehensive bioinformatics and in vitro studies.
PSMC5 insufficiency and P320R mutation impair proteasome function.
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
The Identification of Nuclear FMRP Isoform Iso6 Partners.
Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx.
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.
PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism.
NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma.
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Cancer vulnerabilities unveiled by genomic loss.
Gong Q, Zhao W, Wang T, Pan Y, Cui C, Qu Y, Zhou X
The Journal of biological chemistry 2026 Mar;302(3):111182
The Journal of biological chemistry 2026 Mar;302(3):111182
N-acetylcysteine suppresses proteasome pathway activation and muscular damage induced by microplastics and chromium nanoparticles.
Dai J, Du Y, Wang Y, Yang G
Environmental pollution (Barking, Essex : 1987) 2026 Jan 1;388:127387
Environmental pollution (Barking, Essex : 1987) 2026 Jan 1;388:127387
Mechanism insights into the role of Smc5/6 in HBV inhibition.
He L, Shen H, Zhao A, Pan Y, Ma J, Ouyang Z
International journal of biological macromolecules 2026 Apr;354:151307
International journal of biological macromolecules 2026 Apr;354:151307
RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein.
Xu J, Song H, Xu F, Gao Y, Jiang H, Tan G
Frontiers in microbiology 2025;16:1548061
Frontiers in microbiology 2025;16:1548061
The S273R protein of African swine fever virus antagonizes the canonical NF-κB signaling pathway by IκBα.
Ren H, Shi L-F, Wang Y, Pan X-Y, Li S, Ma Y-H, Fan J-H, Chen X, Yang Z-Y, Fan S, Zhang Y, Han S, He W-R, Wan B, Qiu H-J, Zhang G-P
Journal of virology 2025 May 20;99(5):e0222524
Journal of virology 2025 May 20;99(5):e0222524
Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14(☆).
Shen M, Chen L, Jiang J, Wang Z, Gong Q, Zhang X, Ke X, Qu Y
Pharmacological research 2025 Jun;216:107745
Pharmacological research 2025 Jun;216:107745
Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model.
Skóra B, Szychowski KA
Neurochemistry international 2025 Jul;187:105992
Neurochemistry international 2025 Jul;187:105992
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
He C, Tang C, Guo J, Yin X, Zhu Q, Fang C
Journal of translational medicine 2025 Aug 19;23(1):939
Journal of translational medicine 2025 Aug 19;23(1):939
Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin.
Liao X, Xie Q, Liang M, Liao Q, Huang B, Zhang S, Zhang F, Wang L, Yuan L, Liu X, Wen S, Luo C, Wang D, Chen Y, Luo H, Shu Y
Signal transduction and targeted therapy 2025 Apr 23;10(1):131
Signal transduction and targeted therapy 2025 Apr 23;10(1):131
PSMD2 overexpression as a biomarker for resistance and prognosis in renal cell carcinoma treated with immune checkpoint and tyrosine kinase inhibitors.
Xu X, Wang J, Wang Y, Zhu Y, Wang J, Guo J
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1943-1956
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1943-1956
The proteasome activator subunit PSME1 promotes HBV replication by inhibiting the degradation of HBV core protein.
Liu Y, Yang J, Wang Y, Zeng Q, Fan Y, Huang A, Fan H
Genes & diseases 2024 Nov;11(6):101142
Genes & diseases 2024 Nov;11(6):101142
Identification of PSMD2 as a promising biomarker for pancreatic cancer patients based on comprehensive bioinformatics and in vitro studies.
Feng X, Liu Q, Li H, Yang J, Linghu E
Heliyon 2024 Nov 30;10(22):e40117
Heliyon 2024 Nov 30;10(22):e40117
PSMC5 insufficiency and P320R mutation impair proteasome function.
Yu ZQ, Carmichael J, Collins GA, D'Agostino MD, Lessard M, Firth HV, Harijan P, Fry AE, Dean J, Zhang J, Kini U, Goldberg AL, Rubinsztein DC
Human molecular genetics 2024 Aug 18;33(17):1506-1523
Human molecular genetics 2024 Aug 18;33(17):1506-1523
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation.
Zhang Q, Feng P, Zhu XH, Zhou SQ, Ye ML, Yang XJ, Gong S, Huang SY, Tan XR, He SW, Li YQ
Cell death & disease 2023 Oct 24;14(10):697
Cell death & disease 2023 Oct 24;14(10):697
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
The Identification of Nuclear FMRP Isoform Iso6 Partners.
Ledoux N, Lelong EIJ, Simard A, Hussein S, Adjibade P, Lambert JP, Mazroui R
Cells 2023 Dec 9;12(24)
Cells 2023 Dec 9;12(24)
Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx.
Zhang Y, Li L, Cheng ST, Qin YP, He X, Li F, Wu DQ, Ren F, Yu HB, Liu J, Chen J, Ren JH, Zhang ZZ
Frontiers in microbiology 2022;13:850087
Frontiers in microbiology 2022;13:850087
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
Gu C, Wang Y, Zhang L, Qiao L, Sun S, Shao M, Tang X, Ding P, Tang C, Cao Y, Zhou Y, Guo M, Wei R, Li N, Xiao Y, Duan J, Yang Y
Journal of experimental & clinical cancer research : CR 2022 Jan 6;41(1):11
Journal of experimental & clinical cancer research : CR 2022 Jan 6;41(1):11
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.
Pu M, Tai Y, Yuan L, Zhang Y, Guo H, Hao Z, Chen J, Qi X, Wang G, Tao Z, Ren J
Cellular and molecular life sciences : CMLS 2022 Aug 29;79(9):501
Cellular and molecular life sciences : CMLS 2022 Aug 29;79(9):501
PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism.
Tan Y, Jin Y, Wu X, Ren Z
BMC molecular biology 2019 Nov 8;20(1):24
BMC molecular biology 2019 Nov 8;20(1):24
NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma.
Zhou HZ, Zeng HQ, Yuan D, Ren JH, Cheng ST, Yu HB, Ren F, Wang Q, Qin YP, Huang AL, Chen J
Cell communication and signaling : CCS 2019 Dec 16;17(1):168
Cell communication and signaling : CCS 2019 Dec 16;17(1):168
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Sparks A, Dayal S, Das J, Robertson P, Menendez S, Saville MK
Oncogene 2014 Sep 18;33(38):4685-96
Oncogene 2014 Sep 18;33(38):4685-96
Cancer vulnerabilities unveiled by genomic loss.
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC
Cell 2012 Aug 17;150(4):842-54
Cell 2012 Aug 17;150(4):842-54
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PSMD2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PSMD2. This antibody recognizes human, mouse, rat antigen. The PSMD2 antibody has been validated for the following applications: ELISA, WB analysis.
