Tissue expression
Cell line expression
Protein structure

PSMD2

Proteasome 26S subunit, non-ATPase 2
MGC14274, P97, Rpn1, S2, TRAP2 
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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688 antibodies from 36 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
53 antibodies
Proteintech Group
2 antibodies
Novus Biologicals
29 antibodies
St John's Laboratory
4 antibodies
Everest Biotech
1 antibody
Biorbyt
101 antibodies
antibodies-online
193 antibodies
OriGene
43 antibodies
Cusabio Biotech Co., Ltd
10 antibodies
Affinity Biosciences
5 antibodies
Atlas Antibodies
1 antibody
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Boster Biological Technology
3 antibodies
Bioworld Technology, Inc
3 antibodies
GeneTex
4 antibodies
Bethyl Laboratories
2 antibodies
Abnova Corporation
5 antibodies
Arigo
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Antibodies.com
1 antibody
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
2 antibodies
NSJ Bioreagents
1 antibody
Abbexa
18 antibodies
United States Biological
74 antibodies
Abiocode, Inc.
3 antibodies
MyBioSource
8 antibodies
Cell Signaling Technology, Inc
2 antibodies
Creative Diagnostics
12 antibodies
Creative Biolabs
7 antibodies
ProSci
1 antibody
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
5 antibodies