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- References [6]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11783-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11783-1-AP, RRID:AB_2173378
- Product name
- PTPN22 antibody
- Antibody type
- Polyclonal
- Description
- PTPN22 antibody (Cat. #11783-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PTPN22 as a therapeutic target in intervertebral disc degeneration: Modulating mitophagy and pyroptosis through the PI3K/AKT/mTOR axis.
TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism.
NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome.
TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22.
The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.
Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons.
Liang H, Yang S, Huang Y, Zhu Y, Wu Q, Wu Z, Li S, Shi Y, Chen Z, Jin H, Wang X
Journal of advanced research 2026 Feb;80:775-789
Journal of advanced research 2026 Feb;80:775-789
TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism.
Gunderson AJ, Jordan K, Yamazaki T, Raué HP, Kramer G, Fox N, Slifka MK, Gough MJ, Crittenden MR, Young KH
Journal of immunology (Baltimore, Md. : 1950) 2025 Dec 1;214(12):3647-3657
Journal of immunology (Baltimore, Md. : 1950) 2025 Dec 1;214(12):3647-3657
NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome.
Hayakawa K, Formica AM, Zhou Y, Ichikawa D, Asano M, Li YS, Shinton SA, Brill-Dashoff J, Núñez G, Hardy RR
The Journal of experimental medicine 2017 Oct 2;214(10):3067-3083
The Journal of experimental medicine 2017 Oct 2;214(10):3067-3083
TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22.
Wallis AM, Wallace EC, Hostager BS, Yi Z, Houtman JCD, Bishop GA
Scientific reports 2017 May 18;7(1):2081
Scientific reports 2017 May 18;7(1):2081
The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.
Lin WW, Yi Z, Stunz LL, Maine CJ, Sherman LA, Bishop GA
Science signaling 2015 Sep 1;8(392):ra88
Science signaling 2015 Sep 1;8(392):ra88
Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons.
Varga A, Jenes A, Marczylo TH, Sousa-Valente J, Chen J, Austin J, Selvarajah S, Piscitelli F, Andreou AP, Taylor AH, Kyle F, Yaqoob M, Brain S, White JP, Csernoch L, Di Marzo V, Buluwela L, Nagy I
Pflugers Archiv : European journal of physiology 2014 Jul;466(7):1421-35
Pflugers Archiv : European journal of physiology 2014 Jul;466(7):1421-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 11783-1-AP(PTPN22 antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PTPN22 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PTPN22. This antibody recognizes human,mouse,rat antigen. The PTPN22 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
