Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 17436-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17436-1-AP, RRID:AB_2265702
- Product name
- Leptin antibody
- Antibody type
- Polyclonal
- Description
- Leptin antibody (Cat. #17436-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integration of non-targeted metabolomics and transcriptomics reveals the mechanistic rationale of Coptidis Rhizoma's cold property via systemic energy homeostasis and adaptive thermogenesis in mice.
Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study.
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Leptin decreases Th17/Treg ratio to facilitate neuroblastoma via inhibiting long-chain fatty acid catabolism in tumor cells.
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Inflammatory arthritis increases the susceptibility to acute immune-mediated hepatitis in mice through enhancing leptin expression in T cells.
Leptin, Leptin Receptor, KHDRBS1 (KH RNA Binding Domain Containing, Signal Transduction Associated 1), and Adiponectin in Bone Metastasis from Breast Carcinoma: An Immunohistochemical Study.
Polydatin Inhibits Adipose Tissue Inflammation and Ameliorates Lipid Metabolism in High-Fat-Fed Mice.
Leptin Promotes Monosodium Urate Crystal-Induced Inflammation in Human and Murine Models of Gout.
Xie R, Liu Y, Song Q, Song L, Li J, Zhang Y, Meng J, Dou B, Hu X, Gao L, Zhao Q, Huo H, Sui F
Journal of ethnopharmacology 2026 May 10;362:121344
Journal of ethnopharmacology 2026 May 10;362:121344
Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study.
Xiao M, Li X, Bu F, Ma S, Yang X, Chen J, Zhao Y, Cananzi F, Luo C, Min L
eLife 2025 May 23;14
eLife 2025 May 23;14
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Ouyang P, Qi J, Tong B, Li Y, Cao J, Wang L, Niu T, Qi X
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Leptin decreases Th17/Treg ratio to facilitate neuroblastoma via inhibiting long-chain fatty acid catabolism in tumor cells.
Li M, Li D, Wang HY, Zhang W, Zhuo Z, Guo H, Liu J, Zhuo Y, Tang J, He J, Miao L
Oncoimmunology 2025 Dec;14(1):2460281
Oncoimmunology 2025 Dec;14(1):2460281
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Wang Z, Bi M, Zhe X, Wang X, Dai B, Han X, Ren B, Liang H, Liu D
Cell death discovery 2024 Feb 22;10(1):95
Cell death discovery 2024 Feb 22;10(1):95
Inflammatory arthritis increases the susceptibility to acute immune-mediated hepatitis in mice through enhancing leptin expression in T cells.
Wang Y, Wang P, Xu Q, Dong L, Liu Y, Chen Y, Zhou J, Lu X, Zuo D, Chen Q
Molecular immunology 2021 Dec;140:97-105
Molecular immunology 2021 Dec;140:97-105
Leptin, Leptin Receptor, KHDRBS1 (KH RNA Binding Domain Containing, Signal Transduction Associated 1), and Adiponectin in Bone Metastasis from Breast Carcinoma: An Immunohistochemical Study.
Maroni P, Luzzati A, Perrucchini G, Cannavò L, Bendinelli P
Biomedicines 2020 Nov 17;8(11)
Biomedicines 2020 Nov 17;8(11)
Polydatin Inhibits Adipose Tissue Inflammation and Ameliorates Lipid Metabolism in High-Fat-Fed Mice.
Zheng L, Wu J, Mo J, Guo L, Wu X, Bao Y
BioMed research international 2019;2019:7196535
BioMed research international 2019;2019:7196535
Leptin Promotes Monosodium Urate Crystal-Induced Inflammation in Human and Murine Models of Gout.
Yu Y, Yang J, Fu S, Xue Y, Liang M, Xuan D, Zhu X, Wan W, Lv L, Zou H
Journal of immunology (Baltimore, Md. : 1950) 2019 May 1;202(9):2728-2736
Journal of immunology (Baltimore, Md. : 1950) 2019 May 1;202(9):2728-2736
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human adipose tissue were subjected to SDS PAGE followed by western blot with 17436-1-AP(LEP antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The leptin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human leptin. This antibody recognizes human antigen. The leptin antibody has been validated for the following applications: ELISA, WB, IHC analysis.