LEP

gene product
OB, OBS
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Knockdown Initiative

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated in Knockdown Initative
Eligible for validation in KDI
779 antibodies from 36 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeKDWBELICCIPIHCFC
antibodies-online
260 antibodies
Invitrogen Antibodies
16 antibodies
Novus Biologicals
17 antibodies
R&D Systems
7 antibodies
Acris Antibodies GmbH
31 antibodies
Abgent
7 antibodies
NSJ Bioreagents
3 antibodies
Abnova Corporation
12 antibodies
LifeSpan BioSciences, Inc.
133 antibodies
OriGene
6 antibodies
Aviva Systems Biology
19 antibodies
Enzo Life Sciences
6 antibodies
NovoPro Bioscience Inc.
10 antibodies
Proteintech Group
1 antibody
GeneTex
21 antibodies
Bioworld Technology, Inc
1 antibody
Biorbyt
57 antibodies
ReliaTech GmbH
2 antibodies
MyBioSource
14 antibodies
United States Biological
54 antibodies
Sino Biological Inc.
3 antibodies
Atlas Antibodies
1 antibody
BioLegend
1 antibody
Santa Cruz Biotechnology
1 antibody
Abbiotec
5 antibodies
RayBiotech, Inc.
4 antibodies
PeproTech Inc.
3 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
GenWay
32 antibodies
EMD Millipore
4 antibodies
St John's Laboratory
2 antibodies
Sigma-Aldrich
5 antibodies
BosterBio
1 antibody
Creative Biolabs
1 antibody
Exalpha Biologicals, Inc.
1 antibody