LEP

gene product
OB, OBS
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
994 antibodies from 39 providers.

Antibody properties

Applications

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AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
260 antibodies
Novus Biologicals
75 antibodies
Invitrogen Antibodies
16 antibodies
Acris Antibodies GmbH
31 antibodies
OriGene
33 antibodies
Abgent
7 antibodies
NSJ Bioreagents
3 antibodies
R&D Systems
6 antibodies
LifeSpan BioSciences, Inc.
219 antibodies
GeneTex
24 antibodies
Aviva Systems Biology
19 antibodies
Enzo Life Sciences
6 antibodies
NovoPro Bioscience Inc.
10 antibodies
Biorbyt
65 antibodies
Proteintech Group
1 antibody
Abnova Corporation
13 antibodies
Bioworld Technology, Inc
1 antibody