LEP

gene product
OB, OBS
This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]
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antibodies-online
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Invitrogen Antibodies
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Abgent
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GeneTex
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Boster Biological Technology
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Abnova Corporation
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Affinity Biosciences
1 antibody
Proteintech Group
1 antibody
Bioworld Technology, Inc
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Creative Biolabs
96 antibodies
Abbkine Scientific Co.Ltd.
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ReliaTech GmbH
2 antibodies
MyBioSource
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United States Biological
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ProSci
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Sino Biological Inc.
3 antibodies
BioLegend
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Santa Cruz Biotechnology
1 antibody
St John's Laboratory
6 antibodies
Creative Diagnostics
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Rockland Immunochemicals, Inc.
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Abbiotec
5 antibodies
RayBiotech, Inc.
4 antibodies
PeproTech Inc.
3 antibodies
GenWay
32 antibodies
Abbexa
4 antibodies
EMD Millipore
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Sigma-Aldrich
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Exalpha Biologicals, Inc.
1 antibody