518504

antibody from BioLegend

Targeting: CFH ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS

Western blot

ELISA

Antibody data

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Validation data

Product number: 518504 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#518504, RRID:AB_10900637
Product name: Biotin anti-human Factor H
Antibody type: Monoclonal
Antigen: Human Complement Factor H
Description: Factor H, a 155 kD soluble glycoprotein, is a member of the regulators of complement activation family and is a complement control protein. It circulates in human plasma at a concentration of 500–800 mg/ml that provides critical negative regulation to the alternative pathway of complement cascade. Factor H is secreted by Kupffer cells, hepatocytes, vascular endothelial cells, and platelets. Overactive factor H may result in reduced complement activity on pathogenic cells, increasing susceptibility to microbial infections. Underactive factor H may result in increased complement activity on healthy host cells, resulting in autoimmune diseases.
Reactivity: Human
Host: Mouse
Conjugate: Biotin
Isotype: IgG
Vial size: 500 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CFH protein structure - 518504 shown in red.