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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Product number
- 2531 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#2531, RRID:AB_330330
- Product name
- Phospho-AMPKα (Thr172) Antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Storage
- -20°C
Submitted references A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.
Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans.
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.
Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity.
Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs.
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
AMP-activated protein kinase plays a role in the control of food intake.
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL
Nature cell biology 2013 Oct;15(10):1186-96
Nature cell biology 2013 Oct;15(10):1186-96
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.
Fullerton MD, Galic S, Marcinko K, Sikkema S, Pulinilkunnil T, Chen ZP, O'Neill HM, Ford RJ, Palanivel R, O'Brien M, Hardie DG, Macaulay SL, Schertzer JD, Dyck JR, van Denderen BJ, Kemp BE, Steinberg GR
Nature medicine 2013 Dec;19(12):1649-54
Nature medicine 2013 Dec;19(12):1649-54
Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans.
Morales-Alamo D, Ponce-González JG, Guadalupe-Grau A, Rodríguez-García L, Santana A, Cusso MR, Guerrero M, Guerra B, Dorado C, Calbet JA
Journal of applied physiology (Bethesda, Md. : 1985) 2012 Sep;113(6):917-28
Journal of applied physiology (Bethesda, Md. : 1985) 2012 Sep;113(6):917-28
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.
Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M
Cancer research 2006 Nov 1;66(21):10269-73
Cancer research 2006 Nov 1;66(21):10269-73
Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity.
Gonzalez AA, Kumar R, Mulligan JD, Davis AJ, Weindruch R, Saupe KW
American journal of physiology. Endocrinology and metabolism 2004 Nov;287(5):E1032-7
American journal of physiology. Endocrinology and metabolism 2004 Nov;287(5):E1032-7
Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs.
Pilon G, Dallaire P, Marette A
The Journal of biological chemistry 2004 May 14;279(20):20767-74
The Journal of biological chemistry 2004 May 14;279(20):20767-74
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
AMP-activated protein kinase plays a role in the control of food intake.
Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ
The Journal of biological chemistry 2004 Mar 26;279(13):12005-8
The Journal of biological chemistry 2004 Mar 26;279(13):12005-8
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.
Zou MH, Hou XY, Shi CM, Kirkpatick S, Liu F, Goldman MH, Cohen RA
The Journal of biological chemistry 2003 Sep 5;278(36):34003-10
The Journal of biological chemistry 2003 Sep 5;278(36):34003-10
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.
Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB
Nature 2002 Jan 17;415(6869):339-43
Nature 2002 Jan 17;415(6869):339-43
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