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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN967842 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Janus Kinase 1 (JAK1) (AA 551-766) antibody
- Antibody type
- Monoclonal
- Antigen
- Human JAK1
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 551-766
- Isotype
- IgG
- Antibody clone number
- bcl2-100-D5
- Vial size
- 150 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells.
Regulation of STAT protein synthesis by c-Cbl.
Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation.
Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation.
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.
Kopantzev Y, Heller M, Swaminathan N, Rudikoff S
Oncogene 2002 Oct 3;21(44):6791-800
Oncogene 2002 Oct 3;21(44):6791-800
Regulation of STAT protein synthesis by c-Cbl.
Blesofsky WA, Mowen K, Arduini RM, Baker DP, Murphy MA, Bowtell DD, David M
Oncogene 2001 Nov 1;20(50):7326-33
Oncogene 2001 Nov 1;20(50):7326-33
Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation.
Kawazoe Y, Naka T, Fujimoto M, Kohzaki H, Morita Y, Narazaki M, Okumura K, Saitoh H, Nakagawa R, Uchiyama Y, Akira S, Kishimoto T
The Journal of experimental medicine 2001 Jan 15;193(2):263-9
The Journal of experimental medicine 2001 Jan 15;193(2):263-9
Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation.
Nicholson SE, Oates AC, Harpur AG, Ziemiecki A, Wilks AF, Layton JE
Proceedings of the National Academy of Sciences of the United States of America 1994 Apr 12;91(8):2985-8
Proceedings of the National Academy of Sciences of the United States of America 1994 Apr 12;91(8):2985-8
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.
Müller M, Briscoe J, Laxton C, Guschin D, Ziemiecki A, Silvennoinen O, Harpur AG, Barbieri G, Witthuhn BA, Schindler C
Nature 1993 Nov 11;366(6451):129-35
Nature 1993 Nov 11;366(6451):129-35
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