Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362145 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362145, RRID:AB_10955670
- Product name
- anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr1022 (K-E-Y (p) -Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr1022
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway.
Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling.
Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.
Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide.
Liu D, Huang Y, Zeng J, Chen B, Huang N, Guo N, Liu L, Xu H, Mo X, Li W
Journal of cancer research and clinical oncology 2011 Nov;137(11):1629-40
Journal of cancer research and clinical oncology 2011 Nov;137(11):1629-40
Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling.
Cha Y, Moon BH, Lee MO, Ahn HJ, Lee HJ, Lee KA, Fornace AJ Jr, Kim KS, Cha HJ, Park KS
Stem cells (Dayton, Ohio) 2010 Sep;28(9):1476-86
Stem cells (Dayton, Ohio) 2010 Sep;28(9):1476-86
Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.
Zheng H, Hu P, Quinn DF, Wang YK
Molecular & cellular proteomics : MCP 2005 Jun;4(6):721-30
Molecular & cellular proteomics : MCP 2005 Jun;4(6):721-30
Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide.
Wang R, Griffin PR, Small EC, Thompson JE
Archives of biochemistry and biophysics 2003 Feb 1;410(1):7-15
Archives of biochemistry and biophysics 2003 Feb 1;410(1):7-15
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