ABIN362701

antibody from antibodies-online

Targeting: JAK1 JAK1A, JAK1B, JTK3

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362701

Provider

antibodies-online

Product name

anti-Janus Kinase 1 (JAK1) (AA 1020-1024) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 1020-1024 (K-E-Y-Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 1020-1024

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway.

Liu D, Huang Y, Zeng J, Chen B, Huang N, Guo N, Liu L, Xu H, Mo X, Li W
Journal of cancer research and clinical oncology 2011 Nov;137(11):1629-40

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Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography.

Zheng H, Hu P, Quinn DF, Wang YK
Molecular & cellular proteomics : MCP 2005 Jun;4(6):721-30

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Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide.

Wang R, Griffin PR, Small EC, Thompson JE
Archives of biochemistry and biophysics 2003 Feb 1;410(1):7-15