Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB13238 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13238, RRID:AB_10549042
- Product name
- APH1A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of APH1A.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos.
Ma G, Li T, Price DL, Wong PC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Jan 5;25(1):192-8
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Jan 5;25(1):192-8
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Journal of neuroscience research 2004 Aug 1;77(3):309-22
APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos.
Goutte C, Tsunozaki M, Hale VA, Priess JR
Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22;99(2):775-9
Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22;99(2):775-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of APH1A in human brain tissue lysate with APH1A polyclonal antibody (Cat # PAB13238) at (A) 0.5 and (B) 1 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of APH1A in human brain tissue with APH1A polyclonal antibody (Cat # PAB13238) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)