Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18240 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18240, RRID:AB_10715745
- Product name
- EIF4G1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of EIF4G1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Protection of cap-dependent protein synthesis in vivo and in vitro with an eIF4G-1 variant highly resistant to cleavage by Coxsackievirus 2A protease.
The histone 3'-terminal stem-loop-binding protein enhances translation through a functional and physical interaction with eukaryotic initiation factor 4G (eIF4G) and eIF3.
eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation, and translation of structured mRNAs.
Zhao X, Lamphear BJ, Xiong D, Knowlton K, Rhoads RE
The Journal of biological chemistry 2003 Feb 14;278(7):4449-57
The Journal of biological chemistry 2003 Feb 14;278(7):4449-57
The histone 3'-terminal stem-loop-binding protein enhances translation through a functional and physical interaction with eukaryotic initiation factor 4G (eIF4G) and eIF3.
Ling J, Morley SJ, Pain VM, Marzluff WF, Gallie DR
Molecular and cellular biology 2002 Nov;22(22):7853-67
Molecular and cellular biology 2002 Nov;22(22):7853-67
eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation, and translation of structured mRNAs.
Gallie DR, Browning KS
The Journal of biological chemistry 2001 Oct 5;276(40):36951-60
The Journal of biological chemistry 2001 Oct 5;276(40):36951-60
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of HeLa cells, using EIF4G1 polyclonal antibody (Cat # PAB18240).Peptide "+" means "peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using EIF4G1 polyclonal antibody (Cat # PAB18240).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)