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Cell line expression
Protein structure
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1EIF4F, EIF4G, p220, PARK18
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Top validated antibodies |
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| Proteintech Group |  15704-1-AP |
22 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Atlas Antibodies | HPA028487 |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | MA5-14971 |
Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| LSBio | LS-C349236 |
Polyclonal |
WB
ICC
IHC
|
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| NSJ Bioreagents | RQ5515 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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