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- Antigen structure
- References [192]
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- Product number
- 60269-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- IL-10 antibody
- Antibody type
- Monoclonal
- Description
- IL-10 antibody (Cat. #60269-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 8E4B6
- Vial size
- 20ul, 150ul
Submitted references Stem cell therapy targets THBS1 to reverse endometrial fibrosis.
Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.
Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
Remote neuromuscular electrical stimulation upregulates MDK to enhance macrophage efferocytosis via LRP1 in wound healing.
Tailored Extracellular Matrix-Biomimetic Coating Favors Tissue Healing by Modulating the Microenvironment.
Revolutionizing nephrocalcinosis treatment: IL-10 engineered macrophages as a novel therapeutic approach.
Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
CD44 is associated with papillary thyroid carcinoma metastasis via potential modulation of the immunosuppressive tumor microenvironment.
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Exosomes derived from bone marrow mesenchymal stem cells facilitate repair of radiation-Induced skin injury by attenuating inflammation and apoptosis.
Structural and functional foetal renal abnormalities as a mechanism of oligohydramnios in a guinea pig model of growth restriction.
A tri-component hydrogel composed of Bletilla striata polysaccharide, carboxymethyl chitosan and cinnamaldehyde: Potent enhancement of diabetic wound healing.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Spatiotemporal piezoelectric microspheres for wireless endometrial repair with improved pregnancy outcomes.
Multi-Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling.
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Exploring the Mechanisms of Lijin Fang on Treg/Th17 Cell Imbalance in COPD Based on Network Pharmacology.
Modified Sijunzi Decoction Inhibits Pancreatic Cancer Progression and Improves Immune Suppression: Network Pharmacology and Experimental Validation.
Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells.
Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-κB Signaling Pathway.
Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.
Machine learning identifies PYGM as a macrophage polarization-linked metabolic biomarker in rectal cancer prognosis.
Combined single-cell RNA-seq and bulk RNA-seq construction of M2 TAMs signature for predicting HNSCC prognosis and immunotherapy.
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Two-in-one: multifunctional poloxamer hydrogel accelerates endometrial regeneration and fertility restoration through synergistic regulation of KGF-2 and NO.
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
Garlic essential oil alleviate oxidative stress, inflammation and microbiota dybiosis from small intestinal damage in lipopolysaccharide-challenged weaned piglets.
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
Propionate alleviated colitis by modulating iron homeostasis to inhibit ferroptosis and macrophage polarization.
Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner.
Dysbiosis of the gut microbiome may contribute to the pathogenesis of oral lichen planus through Treg dysregulation.
Interleukin 10 enhances endothelial progenitor cell-mediated angiogenesis in extrahepatic portal venous obstruction.
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Protamine-loaded quaternized chitosan hydrogel dressing featuring antibacterial and antioxidant properties for promoting postoperative periodontal wound healing.
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
A thermally stable bioactive chitosan scaffold with pH-responsive exosome adsorption and release function promotes wound healing.
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Bio-Mimicking Nanoparticle System Facilitates Sonodynamic-Mediated Clearance of Extensively Drug-Resistant Bacteria.
Geraniin attenuates isoproterenol-induced cardiac hypertrophy by inhibiting inflammation, oxidative stress and cellular apoptosis.
Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity.
Role of Adiponectin in Regulating Cytokines and Its Contribution to the Occurrence and Progression of Clinical Mastitis in Holstein Cows.
Roquin-1 interaction with Regnase-1 inhibits the progression of rheumatoid arthritis via suppressing FGF2 expression and NF-κB pathway.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
Exploring the immunomodulatory mechanism of total glucosides of paeony on Sjögren's syndrome dry eye disease based on the "gut-eye axis" pathway.
HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway.
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
Smilax china L. Rhizome extract enhances anti-tumor immune responses by resetting M2-like macrophages and tumor-associated macrophages to M1-like via ERK1/2 signaling.
Quercetin protects against neuronal toxicity by activating the PI3K/Akt/GSK-3β pathway in vivo models of MPTP-induced Parkinson's disease.
Indolepropionic acid modulates the immune response in allergic rhinitis through the AKT/CEBPB/IL‑10 signaling pathway.
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Overexpression of TAFA4 in the dorsal root ganglion ameliorates neuropathic pain in male rats through promoting macrophage M2-Skewing.
Leucine-Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF-κB Pathway.
Mitophagy-mtROS axis contributes to anti-tuberculosis-induced liver injury through activation of the cGAS-STING pathway in rat hepatocytes.
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Multifunctional Scaffold Comprising Metal-Organic Framework, Hydrogel, and Demineralized Bone Matrix for the Treatment of Steroid-Induced Femoral Head Necrosis.
Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma.
Harnessing Extracellular Vesicles for Stabilized and Functional IL-10 Delivery in Macrophage Immunomodulation.
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
Senescent Fibroblasts Drive FAP/OLN Imbalance Through mTOR Signaling to Exacerbate Inflammation and Bone Resorption in Periodontitis.
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Single-atom nanozyme-based catalytic ROS clearance for efficiently alleviating eczema.
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Eu-Doped TiO(2) Coatings via One-Step In Situ Preparation Enhance Macrophage Polarization and Osseointegration of Implants.
Immunoregulatory electrospinning fiber mediates Macrophage energy metabolism reprogramming to promote burn wound healing.
Hydrogel delivering self-assembled herbal nanoparticles accelerates diabetic wound healing through mitochondrial regulation.
NIR-II Responsive Multifunctional Scaffold Enabling "Kill-Modulation-Build" Synergistic Therapy for Infectious Bone Defects.
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Elevated Body Mass Index Aggravates Histopathological Changes and Postoperative Recurrence Risk in Nasal Polyps.
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Beneficial effects of Dendrobium officinale National Herbal Drink on metabolic immune crosstalk via regulate SCFAs-Th17/Treg.
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis.
Small Intestinal Submucosa Hydrogel Loaded With Gastrodin for the Repair of Achilles Tendinopathy.
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Tetramethylpyrazine-loaded electroconductive hydrogels promote tissue repair after spinal cord injury by protecting the blood-spinal cord barrier and neurons.
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Development of Zn(2+)-controlled expression system for lactic acid bacteria and its application in engineered probiotics.
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation.
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Atractylenolide-III attenuates osteoarthritis by repolarizing macrophages through inactivating TLR4/NF-κB signaling.
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
The Influence of Body Fat Dynamics on Pulmonary Immune Responses in Murine Tuberculosis: Unraveling Sex-Specific Insights.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
ZeXieYin formula alleviates atherosclerosis by inhibiting the MAPK/NF-κB signaling pathway in APOE-/- mice to attenuate vascular inflammation and increase plaque stability.
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Interleukin-10: a novel metabolic inducer of macrophage differentiation and subsequently contributing to improved pregnancy outcomes of mice by orchestrating oxidative phosphorylation metabolism†.
Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics.
D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder.
Network pharmacology and in vivo evidence of the pharmacological mechanism of geniposide in the treatment of atherosclerosis.
Single-Cell Transcriptomic Sequencing Reveals Tissue Architecture and Deciphers Pathological Reprogramming During Retinal Ischemia in Macaca fascicularis.
Co-expression of regulatory B-cell markers, transforming growth factor β and interleukin-10 as a prognostic factor in diffuse large B-cell lymphoma.
Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion.
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
S100A8 promotes tumor progression by inducing phenotypic polarization of microglia through the TLR4/IL-10 signaling pathway in glioma.
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Christensenellaceae minuta modulates epithelial healing via PI3K-AKT pathway and macrophage differentiation in the colitis.
Geraniin Alleviates Mouse Laser-Induced Choroidal Neovascularisation by Inhibiting Choroidal Endothelial Cell ACE2/Ang-(1-7)/MasR/IL-10 Pathway.
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
LC-MS/MS analysis of Shenghui decoction component and its effect on learning and memory and neuroprotection in sleep deprivation model mice.
Investigating the impact of regulatory B cells and regulatory B cell-related genes on bladder cancer progression and immunotherapeutic sensitivity.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Melatonin or vitamin C attenuates lead acetate-induced testicular oxidative and inflammatory damage in mice by inhibiting oxidative stress mediated NF-κB signaling.
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Peripheral Klotho protects the kidney and brain by regulating M2a/M2c macrophage polarization in d-gal-treated aged mice.
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Minocycline, a classic antibiotic, exerts psychotropic effects by normalizing microglial neuroinflammation-evoked tryptophan-kynurenine pathway dysregulation in chronically stressed male mice.
Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2.
Diets Differently Regulate Pulmonary Pathogenesis and Immune Signaling in Mice during Acute and Chronic Mycobacterium tuberculosis Infection.
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway.
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
α-Lipoic acid alleviates myocardial injury and induces M2b macrophage polarization after myocardial infarction via HMGB1/NF-kB signaling pathway.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity.
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
Bu Shen Yi Sui Capsule Promotes Myelin Repair by Modulating the Transformation of A1/A2 Reactive Astrocytes In Vivo and In Vitro.
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis.
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
Identification of hub genes, signaling pathways and immune infiltration of recurrent spontaneous abortion based on bioinformatics analysis with clinical verification.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum.
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
The serum soluble Klotho alleviates cardiac aging and regulates M2a/M2c macrophage polarization via inhibiting TLR4/Myd88/NF-κB pathway.
Effect of metformin in autistic BTBR T + Itpr3tf/J mice administered a high-fat diet.
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Sensory nerves promote corneal inflammation resolution via CGRP mediated transformation of macrophages to the M2 phenotype through the PI3K/AKT signaling pathway.
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis.
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice.
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Plasminogen Activator Urokinase Receptor Implies Immunosuppressive Features and Acts as an Unfavorable Prognostic Biomarker in Glioma.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic.
Molecular changes in peripheral blood involving osteoarthritic joint remodelling.
Bisperoxovanadium induces M2-type macrophages and promotes functional recovery after spinal cord injury.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Yu X, Shi L, Qu M, Zhang Y, Zhang Y, Xu X, Liu L, Wang H, Wang H
Frontiers in cell and developmental biology 2026;14:1766915
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Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.
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Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
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Remote neuromuscular electrical stimulation upregulates MDK to enhance macrophage efferocytosis via LRP1 in wound healing.
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Tailored Extracellular Matrix-Biomimetic Coating Favors Tissue Healing by Modulating the Microenvironment.
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ACS nano 2026 Mar 17;20(10):8902-8920
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Revolutionizing nephrocalcinosis treatment: IL-10 engineered macrophages as a novel therapeutic approach.
Zhao W, Wang K, Chen H, Xu J, Wen L, Wu Y, Chen W, Liu H, Liu Y, Zhang J, Lieske JC, Zhang L, Zhang X, Mai H
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Electroacupuncture at Zusanli (ST36) alleviates paclitaxel-induced neuropathic pain in rats via regulating TLR4 signaling pathway in the spinal cord.
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A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
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CD44 is associated with papillary thyroid carcinoma metastasis via potential modulation of the immunosuppressive tumor microenvironment.
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AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
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Exosomes derived from bone marrow mesenchymal stem cells facilitate repair of radiation-Induced skin injury by attenuating inflammation and apoptosis.
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Scientific reports 2026 Feb 2;16(1):6918
Scientific reports 2026 Feb 2;16(1):6918
Structural and functional foetal renal abnormalities as a mechanism of oligohydramnios in a guinea pig model of growth restriction.
Inatomi A, Katsura D, Tokoro S, Tanaka Y, Nakamura A, Hayashi K, Tsuji S
Scientific reports 2026 Feb 11;16(1)
Scientific reports 2026 Feb 11;16(1)
A tri-component hydrogel composed of Bletilla striata polysaccharide, carboxymethyl chitosan and cinnamaldehyde: Potent enhancement of diabetic wound healing.
Liu L, Yan A, Zeng J, Geng S, Li X, Huang G
Carbohydrate polymers 2026 Feb 1;373:124536
Carbohydrate polymers 2026 Feb 1;373:124536
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
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Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
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Spatiotemporal piezoelectric microspheres for wireless endometrial repair with improved pregnancy outcomes.
Zhao R, Ni S, Tao X, Liu Y, Yang N, Cheng C, Zhu Y, Yang M
Materials today. Bio 2026 Apr;37:102915
Materials today. Bio 2026 Apr;37:102915
Multi-Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling.
Zhang W, Yang Z, Zhang Y, Wang L, Zhang X, Mao J, Dai Y, Yuan Y, Wang M, Yang X, Yu X, Liu J, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 9;:e17770
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 9;:e17770
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.
Wang H, Gan Z, Wang Y, Hu D, Zhang L, Ye F, Duan P
Research (Washington, D.C.) 2025;8:0652
Research (Washington, D.C.) 2025;8:0652
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Ma W, Ma Y, Bai Y, Guo C, Zhang Q, Su X
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Exploring the Mechanisms of Lijin Fang on Treg/Th17 Cell Imbalance in COPD Based on Network Pharmacology.
Li ZH, Chen SN, Pan L, Liu R, Liang W, Luo MQ, Liao HF, Feng J, Wang HZ, Huang YG, Zheng JH
International journal of chronic obstructive pulmonary disease 2025;20:2227-2247
International journal of chronic obstructive pulmonary disease 2025;20:2227-2247
Modified Sijunzi Decoction Inhibits Pancreatic Cancer Progression and Improves Immune Suppression: Network Pharmacology and Experimental Validation.
Zhang Y, Ruan L, Li X, Si W, Yang P, Ba H, Chen Z
Drug design, development and therapy 2025;19:8949-8966
Drug design, development and therapy 2025;19:8949-8966
Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells.
Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W
Drug design, development and therapy 2025;19:303-324
Drug design, development and therapy 2025;19:303-324
Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-κB Signaling Pathway.
Ai Z, Yuan D, Li Y, Cai J, Zhou D, Liu W
Journal of inflammation research 2025;18:10619-10636
Journal of inflammation research 2025;18:10619-10636
Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.
Tian C, Ma A, Song T, Zhao F, Huang J, Gao J, Yan H, Chen X
Frontiers in pharmacology 2025;16:1671678
Frontiers in pharmacology 2025;16:1671678
Machine learning identifies PYGM as a macrophage polarization-linked metabolic biomarker in rectal cancer prognosis.
Xu C, Zhang S, Sun B, Yu Z, Liu H
Frontiers in immunology 2025;16:1639303
Frontiers in immunology 2025;16:1639303
Combined single-cell RNA-seq and bulk RNA-seq construction of M2 TAMs signature for predicting HNSCC prognosis and immunotherapy.
Wang J, Li H, Shi M, Ren C, Wei W, Zhao Q, He X, Yang Z, Wei J, Yang X
Frontiers in immunology 2025;16:1620931
Frontiers in immunology 2025;16:1620931
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Yuan Y, Gao Z, Chen J, Liu Y, Zhou J
Frontiers in genetics 2025;16:1598835
Frontiers in genetics 2025;16:1598835
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Zhang P, Jin M, Zhang L, Cui Y, Dong X, Yang J, Zhang J, Wu H
Frontiers in pharmacology 2025;16:1540835
Frontiers in pharmacology 2025;16:1540835
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Guan X, Han L
Frontiers in oncology 2025;15:1590095
Frontiers in oncology 2025;15:1590095
Two-in-one: multifunctional poloxamer hydrogel accelerates endometrial regeneration and fertility restoration through synergistic regulation of KGF-2 and NO.
Zhang Y, Wang X, Gu Q, Lu C, Zhao Y, Li X
Regenerative biomaterials 2025;12:rbaf062
Regenerative biomaterials 2025;12:rbaf062
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Sun H, Chen Y, Sang X, Liu Q, Yu H, Hu S, Mao Y, Zhang L
Regenerative biomaterials 2025;12:rbaf006
Regenerative biomaterials 2025;12:rbaf006
Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.
Yang H, Zhang C, Li Q, Wu Z, Sun N, Yin W, Fan K, Li H
Frontiers in veterinary science 2025;12:1663508
Frontiers in veterinary science 2025;12:1663508
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
Wei YH, Zhou SM, Zhao W, Chen Q, Wang QH, Yu ML, Wei YY, Hu TJ
Frontiers in veterinary science 2025;12:1539448
Frontiers in veterinary science 2025;12:1539448
Garlic essential oil alleviate oxidative stress, inflammation and microbiota dybiosis from small intestinal damage in lipopolysaccharide-challenged weaned piglets.
Chen Y, Song W, Sun C, Chen Y, Chen X, Chen S, Chen Q, Wang K
Porcine health management 2025 Sep 30;11(1):48
Porcine health management 2025 Sep 30;11(1):48
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
Zhang L, Yan X, Li X, Huang Y, Wang X, Lin J, Zhang H, Liu Z, Guo Q
ACS nano 2025 Sep 23;19(37):33184-33201
ACS nano 2025 Sep 23;19(37):33184-33201
Propionate alleviated colitis by modulating iron homeostasis to inhibit ferroptosis and macrophage polarization.
Yao T, Dong X, Lv J, Fu L, Li L
International immunopharmacology 2025 Sep 23;162:115151
International immunopharmacology 2025 Sep 23;162:115151
Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner.
Chen M, Jiang Y, Yu H, Qi H, Li X, Wang J, Wang A, Li Z, Wang Q, Huang Y, Wang L
Investigative ophthalmology & visual science 2025 Sep 2;66(12):58
Investigative ophthalmology & visual science 2025 Sep 2;66(12):58
Dysbiosis of the gut microbiome may contribute to the pathogenesis of oral lichen planus through Treg dysregulation.
Yokomizo S, Kaneko N, Chen H, Yan L, Tsuji S, Akagawa S, Sameshima J, Sueyoshi T, Nagano H, Miyahara Y, Kamikaseda Y, Kido H, Hayashi Y, Yamauchi M, Kiyoshima T, Goto Y, Ohyama Y, Kaneko K, Moriyama M, Kawano S
Mucosal immunology 2025 Oct;18(5):1013-1026
Mucosal immunology 2025 Oct;18(5):1013-1026
Interleukin 10 enhances endothelial progenitor cell-mediated angiogenesis in extrahepatic portal venous obstruction.
Zhang JS
Stem cell research & therapy 2025 Oct 29;16(1):594
Stem cell research & therapy 2025 Oct 29;16(1):594
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Ju J, Wang C, Nie F, Tian H, Yin Q, Liu J, Wang S, Yang P, Du Y
International endodontic journal 2025 Nov;58(11):1725-1737
International endodontic journal 2025 Nov;58(11):1725-1737
Protamine-loaded quaternized chitosan hydrogel dressing featuring antibacterial and antioxidant properties for promoting postoperative periodontal wound healing.
Huang Y, Yan Z, Chen H, Chen L, Huang Y, Liu X, Wang D, Pan Y, Guo L
International journal of biological macromolecules 2025 Nov;330(Pt 4):148259
International journal of biological macromolecules 2025 Nov;330(Pt 4):148259
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Zhang J, Xu Y, Han X, Gao Y, Wei Z, Sun X
Cancer genetics 2025 Nov;298-299:141-150
Cancer genetics 2025 Nov;298-299:141-150
A thermally stable bioactive chitosan scaffold with pH-responsive exosome adsorption and release function promotes wound healing.
Yuan J, Li M, He X, Hou Q, Fu X, Hao J
International journal of biological macromolecules 2025 May;306(Pt 3):141552
International journal of biological macromolecules 2025 May;306(Pt 3):141552
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
Liu J, Li Z, Liu W, Jiang Z, Zhang X, Yuan Y, Shen Y
International immunopharmacology 2025 May 8;154:114559
International immunopharmacology 2025 May 8;154:114559
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
Zhang SP, Tong M, Mo J, Dong ZY, Huang YF
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
Wang J, Ji L, Gao Y, Sun J, Zhou X, Ding Y, Zhou Z, Guo X, Liu C, Wang Y, Zhang Q, Lv Z, Ma D
Scientific reports 2025 May 27;15(1):18509
Scientific reports 2025 May 27;15(1):18509
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Zhao DP, Xue A, Yuan K, Zuo K, Li Y, Bian ZH, Xu HD, Cheng SM, Yang M, Zhao HM, Ma X, Lei X, Zhang N
Journal of ethnopharmacology 2025 May 12;347:119792
Journal of ethnopharmacology 2025 May 12;347:119792
Bio-Mimicking Nanoparticle System Facilitates Sonodynamic-Mediated Clearance of Extensively Drug-Resistant Bacteria.
Gao F, Zhou R, He Y, Zhang Y, Bao C, Feng G
ACS biomaterials science & engineering 2025 May 12;11(5):2988-3002
ACS biomaterials science & engineering 2025 May 12;11(5):2988-3002
Geraniin attenuates isoproterenol-induced cardiac hypertrophy by inhibiting inflammation, oxidative stress and cellular apoptosis.
Ding J, Zhang S, Li Q, Xia B, Wu J, Lu X, Huang C, Yuan X, You Q
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 May 1;29(3):307-319
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 May 1;29(3):307-319
Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity.
Li S, Yin Y, Dong X, Xu L, Yang Z, Li H, Zou Y, Wu Z
Biological trace element research 2025 Mar;203(3):1539-1554
Biological trace element research 2025 Mar;203(3):1539-1554
Role of Adiponectin in Regulating Cytokines and Its Contribution to the Occurrence and Progression of Clinical Mastitis in Holstein Cows.
Zhang J, Chen N, Yang Z, Gao Y, Zhang B, Li J, Zhou B, Tang Z, Dong W, Zhao X, Zhang Y, Zhang Q
International journal of molecular sciences 2025 Mar 22;26(7)
International journal of molecular sciences 2025 Mar 22;26(7)
Roquin-1 interaction with Regnase-1 inhibits the progression of rheumatoid arthritis via suppressing FGF2 expression and NF-κB pathway.
Wang H, Tang Z, Xie K, Hao T, Su G
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 18;74(1):55
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 18;74(1):55
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
Liao W, Hu R, Ji Y, Zhong Z, Huang X, Cai T, Zhou C, Wang Y, Ye Z, Yang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
Zhang T, Meng Z, Yu H, Ding P, Kai T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
Exploring the immunomodulatory mechanism of total glucosides of paeony on Sjögren's syndrome dry eye disease based on the "gut-eye axis" pathway.
Fu T, Lu W, Wu D, Xu L, Wu G
International ophthalmology 2025 Jun 5;45(1):230
International ophthalmology 2025 Jun 5;45(1):230
HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway.
Yang H, Liu M, Song S, Xu Q, Lee J, Sun J, Xue S, Sun X, Che C
Investigative ophthalmology & visual science 2025 Jun 2;66(6):32
Investigative ophthalmology & visual science 2025 Jun 2;66(6):32
Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps.
Liu Y, Liu Y, Ye Z, Wang X, Li J, Mei PL, Duan L, Wang B, Xu C, Xiong W, He Y, Ye Q
Stem cell research & therapy 2025 Jun 2;16(1):272
Stem cell research & therapy 2025 Jun 2;16(1):272
Smilax china L. Rhizome extract enhances anti-tumor immune responses by resetting M2-like macrophages and tumor-associated macrophages to M1-like via ERK1/2 signaling.
Guo Y, Lin X, Wang P, Wang Y, Chen M, Tang S, Jin L, Mao W, Liu X, Shou Q, Fu H
Journal of ethnopharmacology 2025 Jun 12;349:119983
Journal of ethnopharmacology 2025 Jun 12;349:119983
Quercetin protects against neuronal toxicity by activating the PI3K/Akt/GSK-3β pathway in vivo models of MPTP-induced Parkinson's disease.
Li Y, Man M, Tian Y, Zhao G, Liu F, Zhao J, Huang S, Xue J, Chang W
Inflammopharmacology 2025 Jul;33(7):4063-4076
Inflammopharmacology 2025 Jul;33(7):4063-4076
Indolepropionic acid modulates the immune response in allergic rhinitis through the AKT/CEBPB/IL‑10 signaling pathway.
Gao L, Song Y, Zhang F, Zhao Y, Hu H, Feng Y
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Xie H, Tian S, Cui C, Sun C, Hu Y, Tang C, Gao D, Lu L, Jin L, Xu F, Lin J, Fu H, Liang X, Zhao L, Kong F, Wei X, Sun W, Li M, Li H
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Overexpression of TAFA4 in the dorsal root ganglion ameliorates neuropathic pain in male rats through promoting macrophage M2-Skewing.
Ai Z, Li H, Xu S, Cai C, Wang X, Guan Y, Guo R, Wang Y
Neurochemistry international 2025 Jul;187:105993
Neurochemistry international 2025 Jul;187:105993
Leucine-Rich Repeat Containing 15 Promotes the Inflammatory Response in Rheumatoid Arthritis by Regulating NF-κB Pathway.
Xin M, Xia G, Guan X, Xi G, Fu M
Immunity, inflammation and disease 2025 Jul;13(7):e70220
Immunity, inflammation and disease 2025 Jul;13(7):e70220
Mitophagy-mtROS axis contributes to anti-tuberculosis-induced liver injury through activation of the cGAS-STING pathway in rat hepatocytes.
Chen W, Luo C, Zhou H, Liu Z, Huang J, Liu Y, You M, Yang G
International immunopharmacology 2025 Jul 28;160:114984
International immunopharmacology 2025 Jul 28;160:114984
MICA+ Tumor Cells Modulate Macrophage Phenotype and Function via PPAR/EHHADH-Mediated Fatty Acid Metabolism in Hepatocellular Carcinoma (HCC).
Huang J, Teng Y, Yan P, Yang Y, Lin S, Wu Q, Du Q, Li X, Yao M, Li J, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2025 Jul 16;17(14)
Cancers 2025 Jul 16;17(14)
Multifunctional Scaffold Comprising Metal-Organic Framework, Hydrogel, and Demineralized Bone Matrix for the Treatment of Steroid-Induced Femoral Head Necrosis.
Bai L, Zhang X, Shen W, Wang P, Yin X, Liu J, Xu H, Liu B, Man Z, Li W
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2407758
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2407758
Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma.
Takai M, Shimada K, Furukawa K, Yamaga Y, Yoshiyama S, Kagaya Y, Suzuki T, Hayashi K, Shimada S, Karube K, Kiyoi H
Cancer science 2025 Jan;116(1):214-225
Cancer science 2025 Jan;116(1):214-225
Harnessing Extracellular Vesicles for Stabilized and Functional IL-10 Delivery in Macrophage Immunomodulation.
Saleh NA, Gagea MA, Vitija X, Janovic T, Schmidt JC, Deng CX, Kanada M
bioRxiv : the preprint server for biology 2025 Jan 18;
bioRxiv : the preprint server for biology 2025 Jan 18;
Synergistic Enhancement of Antibacterial and Osteo-Immunomodulatory Activities of Titanium Implants via Dual-Responsive Multifunctional Surfaces.
Wang Q, Gao Y, Chen Y, Wang X, Pei Q, Zhang T, Wang C, Pan J
Advanced healthcare materials 2025 Feb;14(4):e2404260
Advanced healthcare materials 2025 Feb;14(4):e2404260
Senescent Fibroblasts Drive FAP/OLN Imbalance Through mTOR Signaling to Exacerbate Inflammation and Bone Resorption in Periodontitis.
Yin C, Fu L, Guo S, Liang Y, Shu T, Shao W, Xia H, Xia T, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409398
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409398
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Yang ZC, Lin H, Liu GJ, Pan H, Zhu JL, Zhang XH, Gao F, Wang Z, Wang ZH
Stem cell research & therapy 2025 Feb 7;16(1):52
Stem cell research & therapy 2025 Feb 7;16(1):52
Single-atom nanozyme-based catalytic ROS clearance for efficiently alleviating eczema.
Wan Z, Zhe Y, Li J, Liu Q, Ding D, Zhang S, Liu S, Wang H, Yang J, Sun X, Qiao H, Mu X
Journal of materials chemistry. B 2025 Feb 5;13(6):1969-1979
Journal of materials chemistry. B 2025 Feb 5;13(6):1969-1979
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Wang L, Li W, Wu W, Liu Q, You M, Liu X, Ye C, Chen J, Tan Q, Liu G, Du Y
Brain research 2025 Feb 15;1849:149339
Brain research 2025 Feb 15;1849:149339
Eu-Doped TiO(2) Coatings via One-Step In Situ Preparation Enhance Macrophage Polarization and Osseointegration of Implants.
Zhang B, Qu H, Zhang Z, Wang X, Dou Z, Li X, Cao R, Zhang K, Zhang J, Zhang Q
ACS applied materials & interfaces 2025 Feb 12;17(6):8886-8900
ACS applied materials & interfaces 2025 Feb 12;17(6):8886-8900
Immunoregulatory electrospinning fiber mediates Macrophage energy metabolism reprogramming to promote burn wound healing.
Wu H, Wu Q, Liang C, Hua J, Meng L, Nakielski P, Lu C, Pierini F, Xu L, Yu Y, Luo Q
Materials today. Bio 2025 Dec;35:102430
Materials today. Bio 2025 Dec;35:102430
Hydrogel delivering self-assembled herbal nanoparticles accelerates diabetic wound healing through mitochondrial regulation.
Guo J, Hu B, Wei Y, Cheng G, Wang C, Qin X, Chen X, Chen J, Chen Z, Chen T
Materials today. Bio 2025 Dec;35:102417
Materials today. Bio 2025 Dec;35:102417
NIR-II Responsive Multifunctional Scaffold Enabling "Kill-Modulation-Build" Synergistic Therapy for Infectious Bone Defects.
Yang Q, Lou S, Zhang Y, Fang Z, Xing C, Wang W, Han M, Wang Z, Tang BZ, Zhang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e08948
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e08948
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Zhang H, Huang X, Chen R, Lin W, Li L, Peng X, Yang X, Chen X, Guo T, Weng J, Li J, Yuan Q, Tan H, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Ding R, Hu N, Zhang X, Jiang F, Feng Y, Li Z, Tang S, Li W, Shi H, Si Y
Free radical biology & medicine 2025 Dec 1;240:15-28
Free radical biology & medicine 2025 Dec 1;240:15-28
Elevated Body Mass Index Aggravates Histopathological Changes and Postoperative Recurrence Risk in Nasal Polyps.
Jiang S, Liu L, Zhang H, Xie Z, Xie S, Jiang W
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2025 Aug;173(2):522-533
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2025 Aug;173(2):522-533
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Xie J, Du L, Lu Y, Guo X, Zhou X, Tong Y, Shen B, Yu X, Guo F, Yu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Mao Z, Lin X, Hu Y, Liu Y, Yu S, Zhou T, Zhang J, Yang X, Tian S, Miao M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
Xu Y, Wei C, Ma L, Zhao L, Li D, Lin Y, Zhou Q, Xie L, Wang F
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Zhang L, Feng L, Zhao Y, Geng Y, Liu R, Ma Y, Bo W, Xi Y, Tian Z
Life sciences 2025 Apr 1;366-367:123500
Life sciences 2025 Apr 1;366-367:123500
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.
Chen L, Zhang M, Yang X, Wang Y, Huang T, Li X, Ban Y, Li Q, Yang Q, Zhang Y, Zheng Y, Wang D, Wang X, Shi X, Zhang M, Sun Y, Wu J
Theranostics 2024;14(11):4256-4277
Theranostics 2024;14(11):4256-4277
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Sun Y, Wu J, Zhou L, Wang W, Wang H, Sun S, Xu Y, Zhang L, Jiang X, Zhu G, Xi K, Gu Y, Chen L
Frontiers in bioengineering and biotechnology 2024;12:1415527
Frontiers in bioengineering and biotechnology 2024;12:1415527
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Wu H, Zhang L, Dong X, Yang J, Zheng L, Li L, Liu X, Jin M, Zhang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Beneficial effects of Dendrobium officinale National Herbal Drink on metabolic immune crosstalk via regulate SCFAs-Th17/Treg.
Dong YJ, Zhang YP, Jiang XF, Xie ZY, Li B, Jiang NH, Chen SH, Lv GY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155816
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155816
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Zhang X, Hu F, Li J, Chen L, Mao YF, Li QB, Nie CY, Lin C, Xiao J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis.
Liu R, Luo Z, Dai C, Wei Y, Yan S, Kuang X, Qi K, Fu A, Li Y, Fu S, Ma Z, Dai W, Xiao X, Wu Q, Zhou H, Rao Y, Yuan J, Shi T, Deng Z, Chen C, Liu T
Signal transduction and targeted therapy 2024 Oct 21;9(1):292
Signal transduction and targeted therapy 2024 Oct 21;9(1):292
Small Intestinal Submucosa Hydrogel Loaded With Gastrodin for the Repair of Achilles Tendinopathy.
Zhang X, Li M, Mao X, Yao Z, Zhu W, Yuan Z, Gao X, Pan S, Zhang Y, Zhao J, Mao H
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(47):e2401886
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(47):e2401886
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Zhang M, Ye Y, Chen Z, Wu X, Chen Y, Zhao P, Zhao M, Zheng C
Acta biomaterialia 2024 Nov;189:505-518
Acta biomaterialia 2024 Nov;189:505-518
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Yang W, Zhang X, Wang Z, Zheng X, Wu W, Chen Q
International immunopharmacology 2024 Nov 15;141:112883
International immunopharmacology 2024 Nov 15;141:112883
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
Cao W, Zeng Z, Sun J, Chen Y, Kuang F, Luo S, Lan J, Lei S
Communications biology 2024 Nov 13;7(1):1504
Communications biology 2024 Nov 13;7(1):1504
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Wang Y, Chen Y, Zhou T, Li J, Zhang N, Liu N, Zhou P, Mao Y
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
Sun J, Wang X, Xiao J, Yang Q, Huang X, Yang Z, Liu H, Liu Y, Wang H, Huang Z, Ma L, Cao Z
Scientific reports 2024 Nov 1;14(1):26291
Scientific reports 2024 Nov 1;14(1):26291
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Zhou Z, Li Y, Wu S, Liu T, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Tetramethylpyrazine-loaded electroconductive hydrogels promote tissue repair after spinal cord injury by protecting the blood-spinal cord barrier and neurons.
Deng B, Jiang S, Liu G, Li X, Zhao Y, Fan X, Ren J, Ning C, Xu L, Ji L, Mu X
Journal of materials chemistry. B 2024 May 8;12(18):4409-4426
Journal of materials chemistry. B 2024 May 8;12(18):4409-4426
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Song J, Bai H, Chen S, Xing Y, Lou J
Heliyon 2024 May 15;10(9):e30422
Heliyon 2024 May 15;10(9):e30422
Development of Zn(2+)-controlled expression system for lactic acid bacteria and its application in engineered probiotics.
Xu X, Zhang L, Cui Y, Kong J, Guo T
Synthetic and systems biotechnology 2024 Mar;9(1):152-158
Synthetic and systems biotechnology 2024 Mar;9(1):152-158
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
Yu Z, Zhang Q, Wei S, Zhang Y, Zhou T, Zhang Q, Shi R, Zinovkin D, Pranjol ZI, Zhang J, Wang H
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation.
He J, Zhou S, Wang J, Sun B, Ni D, Wu J, Peng X
Journal of nanobiotechnology 2024 Mar 16;22(1):116
Journal of nanobiotechnology 2024 Mar 16;22(1):116
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Huang QM, Long YL, Wang JN, Wu J, Tang WL, Wang XY, Zhang ZH, Zhuo YQ, Guan XH, Deng KY, Xin HB
International immunopharmacology 2024 Mar 10;129:111660
International immunopharmacology 2024 Mar 10;129:111660
Atractylenolide-III attenuates osteoarthritis by repolarizing macrophages through inactivating TLR4/NF-κB signaling.
Yi G, Zhang R, Li M, Song X, Li S
International immunopharmacology 2024 Mar 10;129:111629
International immunopharmacology 2024 Mar 10;129:111629
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis.
Xie Y, Li J, Tao Q, Wu Y, Liu Z, Chen Y, Zeng C
Scientific reports 2024 Jun 7;14(1):13102
Scientific reports 2024 Jun 7;14(1):13102
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
The Influence of Body Fat Dynamics on Pulmonary Immune Responses in Murine Tuberculosis: Unraveling Sex-Specific Insights.
Dhanyalayam D, Thangavel H, Sidrat T, Oswal N, Lizardo K, Mauro M, Zhao X, Xue HH, Desai JV, Nagajyothi JF
International journal of molecular sciences 2024 Jun 21;25(13)
International journal of molecular sciences 2024 Jun 21;25(13)
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
ZeXieYin formula alleviates atherosclerosis by inhibiting the MAPK/NF-κB signaling pathway in APOE-/- mice to attenuate vascular inflammation and increase plaque stability.
Huang R, Sun Y, Liu R, Zhu B, Zhang H, Wu H
Journal of ethnopharmacology 2024 Jun 12;327:117969
Journal of ethnopharmacology 2024 Jun 12;327:117969
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
Liu C, Yu H, Xia H, Wang Z, Li B, Xue H, Jin S, Xiao L, Wu Y, Guo Q
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Mo D, Tang X, Ma Y, Chen D, Xu W, Jiang N, Zheng J, Yan F
Journal of translational medicine 2024 Jul 30;22(1):706
Journal of translational medicine 2024 Jul 30;22(1):706
Interleukin-10: a novel metabolic inducer of macrophage differentiation and subsequently contributing to improved pregnancy outcomes of mice by orchestrating oxidative phosphorylation metabolism†.
Wang H, Wang L, Gong G, Lin X, Luo J, Liu C, Mor G, Liao A
Biology of reproduction 2024 Jul 12;111(1):76-91
Biology of reproduction 2024 Jul 12;111(1):76-91
Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics.
Xie LW, Cai S, Lu HY, Tang FL, Zhu RQ, Tian Y, Li M
Gut microbes 2024 Jan-Dec;16(1):2347722
Gut microbes 2024 Jan-Dec;16(1):2347722
D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder.
Joshi CS, Salazar AM, Wang C, Ligon MM, Chappidi RR, Fashemi BE, Felder PA, Mora A, Grimm SL, Coarfa C, Mysorekar IU
Developmental cell 2024 Jan 8;59(1):33-47.e5
Developmental cell 2024 Jan 8;59(1):33-47.e5
Network pharmacology and in vivo evidence of the pharmacological mechanism of geniposide in the treatment of atherosclerosis.
Ma G, Dong Q, Li F, Jin Z, Pi J, Wu W, Li J
BMC complementary medicine and therapies 2024 Jan 24;24(1):53
BMC complementary medicine and therapies 2024 Jan 24;24(1):53
Single-Cell Transcriptomic Sequencing Reveals Tissue Architecture and Deciphers Pathological Reprogramming During Retinal Ischemia in Macaca fascicularis.
Li L, Zuo S, Liu Y, Yang L, Ge S, Ye F, Chai P, Lu L
Investigative ophthalmology & visual science 2024 Jan 2;65(1):27
Investigative ophthalmology & visual science 2024 Jan 2;65(1):27
Co-expression of regulatory B-cell markers, transforming growth factor β and interleukin-10 as a prognostic factor in diffuse large B-cell lymphoma.
Mishina T, Miyoshi H, Takeuchi M, Miyawaki K, Nakashima K, Yamada K, Moritsubo M, Inoue-Mitsuyama K, Shimasaki Y, Imamoto T, Kawamoto K, Furuta T, Kohno K, Kato K, Akashi K, Ohshima K
Pathology, research and practice 2024 Feb;254:155117
Pathology, research and practice 2024 Feb;254:155117
Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion.
Huang Y, Zheng J, Zeng G, Xu H, Lv Y, Liang X, Jin L, Jiang X
Materials today. Bio 2024 Feb;24:100931
Materials today. Bio 2024 Feb;24:100931
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Zhang W, Sun J, Liu F, Li S, Wang X, Su L, Liu G
Biological trace element research 2024 Feb;202(2):624-642
Biological trace element research 2024 Feb;202(2):624-642
S100A8 promotes tumor progression by inducing phenotypic polarization of microglia through the TLR4/IL-10 signaling pathway in glioma.
Yang Y, Cui H, Li D, Chen L, Liu Y, Zhou C, Li L, Feng M, Chen X, Cao Y, Gao Y
Journal of the National Cancer Center 2024 Dec;4(4):369-381
Journal of the National Cancer Center 2024 Dec;4(4):369-381
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts.
Lv D, Li B, Liu Z, Zhang Q, Cao S, Xu Y, Zhang Z
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Christensenellaceae minuta modulates epithelial healing via PI3K-AKT pathway and macrophage differentiation in the colitis.
Yao T, Wu Y, Fu L, Lv J, Lv L, Li L
Microbiological research 2024 Dec;289:127927
Microbiological research 2024 Dec;289:127927
Geraniin Alleviates Mouse Laser-Induced Choroidal Neovascularisation by Inhibiting Choroidal Endothelial Cell ACE2/Ang-(1-7)/MasR/IL-10 Pathway.
Lu H, Cai Q, Li L, Gu J, Zhang Y, Sun H, Su H, Song L
Journal of cellular and molecular medicine 2024 Dec;28(23):e70228
Journal of cellular and molecular medicine 2024 Dec;28(23):e70228
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Sun X, Xu S, Wang J, Li X, Sun H, Zhao W
Neuroreport 2024 Dec 4;35(17):1107-1116
Neuroreport 2024 Dec 4;35(17):1107-1116
Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM.
Li J, Tian Z, Zhang T, Jin J, Zhang X, Xie P, Lin H, Gu J, Wu Y, Wang X, Zhang S, Yan X, Guo D, Wang Z, Zhang Q
Cellular & molecular biology letters 2024 Dec 3;29(1):148
Cellular & molecular biology letters 2024 Dec 3;29(1):148
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Wang Y, Li H, Sun H, Xu C, Sun H, Wei W, Song J, Jia F, Zhong D, Li G
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Dingyi L, Libin H, Jifeng P, Ding Z, Yulong L, Zhangyi W, Yunong Y, Qinghua W, Feng L
Experimental brain research 2024 Aug;242(8):1917-1932
Experimental brain research 2024 Aug;242(8):1917-1932
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Gao Y, Mao J, Zhang R, Deng Q, Wang Y, Pan Y, Liudi S, Wang Y, Fan X, Yang Y, Wan S
European journal of pharmacology 2024 Aug 15;977:176673
European journal of pharmacology 2024 Aug 15;977:176673
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Shang S, Zhuang K, Chen J, Zhang M, Jiang S, Li W
Bioactive materials 2024 Apr;34:298-310
Bioactive materials 2024 Apr;34:298-310
LC-MS/MS analysis of Shenghui decoction component and its effect on learning and memory and neuroprotection in sleep deprivation model mice.
Wen C, Li ZH, Cheng L, Zheng JZ, Wang P, Chen L, You QY, Ding L
Fitoterapia 2024 Apr;174:105823
Fitoterapia 2024 Apr;174:105823
Investigating the impact of regulatory B cells and regulatory B cell-related genes on bladder cancer progression and immunotherapeutic sensitivity.
Zhou J, Zhou R, Zhu Y, Deng S, Muhuitijiang B, Li C, Shi X, Zhang L, Tan W
Journal of experimental & clinical cancer research : CR 2024 Apr 2;43(1):101
Journal of experimental & clinical cancer research : CR 2024 Apr 2;43(1):101
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice.
Li L, Wang H, Pang S, Wang L, Fan Z, Ma C, Yang S, Banda J, Hui Q, Lv F, Fan H, Huang T, Zhang X, Wang X
The Journal of biological chemistry 2023 Sep;299(9):105127
The Journal of biological chemistry 2023 Sep;299(9):105127
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072
International journal of biological macromolecules 2023 Sep 30;249:126072
Melatonin or vitamin C attenuates lead acetate-induced testicular oxidative and inflammatory damage in mice by inhibiting oxidative stress mediated NF-κB signaling.
Zhao ZM, Mei S, Zheng QY, Wang J, Yin YR, Zhang JJ, Wang XZ
Ecotoxicology and environmental safety 2023 Oct 1;264:115481
Ecotoxicology and environmental safety 2023 Oct 1;264:115481
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration.
Tan J, Zhuo Z, Wang X, Zhang Y, Qian Y, Lin F
International journal of molecular medicine 2023 Nov;52(5)
International journal of molecular medicine 2023 Nov;52(5)
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Wang P, Li T, Niu C, Sun S, Liu D
International immunopharmacology 2023 Mar;116:109763
International immunopharmacology 2023 Mar;116:109763
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Mao LR, Du JP, Wang XC, Xu LF, Zhang YP, Sun QS, Shi ZL, Xing YR, Su YX, Wang SJ, Wang J, Ma JL, Zhang JY
ACS infectious diseases 2023 Mar 10;9(3):593-608
ACS infectious diseases 2023 Mar 10;9(3):593-608
Peripheral Klotho protects the kidney and brain by regulating M2a/M2c macrophage polarization in d-gal-treated aged mice.
Wang Y, Xiong X, Wang K, Bao Y, Zhang T, Ainiwaer D, Wang G, Li H, Sun Z
Tissue & cell 2023 Jun;82:102049
Tissue & cell 2023 Jun;82:102049
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Li C, Sun F, Tian J, Li J, Sun H, Zhang Y, Guo S, Lin Y, Sun X, Zhao Y
Bioactive materials 2023 Jun;24:361-375
Bioactive materials 2023 Jun;24:361-375
Minocycline, a classic antibiotic, exerts psychotropic effects by normalizing microglial neuroinflammation-evoked tryptophan-kynurenine pathway dysregulation in chronically stressed male mice.
Cheng D, Qin ZS, Zheng Y, Xie JY, Liang SS, Zhang JL, Feng YB, Zhang ZJ
Brain, behavior, and immunity 2023 Jan;107:305-318
Brain, behavior, and immunity 2023 Jan;107:305-318
Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2.
Wu S, Tian X, Mao Q, Peng C
Clinical epigenetics 2023 Jan 23;15(1):12
Clinical epigenetics 2023 Jan 23;15(1):12
Diets Differently Regulate Pulmonary Pathogenesis and Immune Signaling in Mice during Acute and Chronic Mycobacterium tuberculosis Infection.
Oswal N, Thangavel H, Lizardo K, Dhanyalayam D, Sidrat T, Salgame P, Nagajyothi JF
Life (Basel, Switzerland) 2023 Jan 13;13(1)
Life (Basel, Switzerland) 2023 Jan 13;13(1)
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H, Lu X, Huang L, He Y, Liu X, Wang Y, Duan C
Metabolic brain disease 2023 Feb;38(2):699-708
Metabolic brain disease 2023 Feb;38(2):699-708
CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway.
Zhang Y, Wei J, Yu X, Chen L, Ren R, Dong Y, Wang S, Zhu M, Ming N, Zhu Z, Gao C, Xiong W
Materials today. Bio 2023 Dec;23:100816
Materials today. Bio 2023 Dec;23:100816
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Bai J, Qian B, Cai T, Chen Y, Li T, Cheng Y, Wu Z, Liu C, Ye M, Du Y, Fu W
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
α-Lipoic acid alleviates myocardial injury and induces M2b macrophage polarization after myocardial infarction via HMGB1/NF-kB signaling pathway.
Wang Y, Zheng Y, Qi B, Liu Y, Cheng X, Feng J, Gao W, Li T
International immunopharmacology 2023 Aug;121:110435
International immunopharmacology 2023 Aug;121:110435
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
Systemic Pharmacology Reveals the Potential Targets and Signaling Mechanisms in the Adjuvant Treatment of Brucellosis with Traditional Chinese Medicine.
Zhao T, Zhang Y, Liu L, Deng X, Guo J, Cao S, Zhu D, Xu J, Nikolaevna UV, Maratbek S, Wang Z, Sun Z, Gu X, Zhang H
ACS omega 2023 Aug 8;8(31):28797-28812
ACS omega 2023 Aug 8;8(31):28797-28812
Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity.
Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T
Immunity 2023 Aug 8;56(8):1939-1954.e12
Immunity 2023 Aug 8;56(8):1939-1954.e12
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Ni R, Luo Y, Jiang L, Mao X, Feng Y, Tuersun S, Hu Z, Zhu Y
International journal of biological macromolecules 2023 Aug 1;245:125556
International journal of biological macromolecules 2023 Aug 1;245:125556
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
Wo B, Du C, Yang Y, Qi H, Liang Z, He C, Yao F, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
Bu Shen Yi Sui Capsule Promotes Myelin Repair by Modulating the Transformation of A1/A2 Reactive Astrocytes In Vivo and In Vitro.
Zha Z, Liu YJ, Liu SS, Zhang N, Li JL, Qi F, Jin LY, Xue B, Yang T, Fan YP, Zhao H, Wang L
Oxidative medicine and cellular longevity 2022;2022:3800004
Oxidative medicine and cellular longevity 2022;2022:3800004
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Yang QQ, Li HN, Xia YT, Tian X, Feng F, Yang J, Xu YL, Guo J, Li XQ, Wang JY, Zeng XY
Frontiers in molecular neuroscience 2022;15:820664
Frontiers in molecular neuroscience 2022;15:820664
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis.
Dong C, Chen W, Zou L, Liu B, Deng K, Guo D, Wang P, Chen H, Wang H, Wang J
Frontiers in microbiology 2022;13:963901
Frontiers in microbiology 2022;13:963901
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Chang Z, Li R, Zhang J, An L, Zhou G, Lei M, Deng J, Yang R, Song Z, Zhong W, Qi D, Duan X, Li S, Sun B, Wu W
Frontiers in immunology 2022;13:1008865
Frontiers in immunology 2022;13:1008865
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
Deng L, Wang S, Zhang R, Huang J, Lin Y, Liu X, Lu Z, Li M, Tan W
International immunopharmacology 2022 Sep;110:108997
International immunopharmacology 2022 Sep;110:108997
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
Gao N, Wang C, Yu Y, Xie L, Xing Y, Zhang Y, Wang Y, Wu J, Cai Y
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
Identification of hub genes, signaling pathways and immune infiltration of recurrent spontaneous abortion based on bioinformatics analysis with clinical verification.
Chen YX, Zhang QQ, Ge C, Yang J
Taiwanese journal of obstetrics & gynecology 2022 Nov;61(6):1027-1036
Taiwanese journal of obstetrics & gynecology 2022 Nov;61(6):1027-1036
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Polydopamine Decorated Microneedles with Fe-MSC-Derived Nanovesicles Encapsulation for Wound Healing.
Ma W, Zhang X, Liu Y, Fan L, Gan J, Liu W, Zhao Y, Sun L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(13):e2103317
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(13):e2103317
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
Tan Z, Yang G, Qiu J, Yan W, Liu Y, Ma Z, Li J, Liu J, Shan N
Molecular neurobiology 2022 May;59(5):3140-3158
Molecular neurobiology 2022 May;59(5):3140-3158
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Mao L, Xu L, Wang X, Xing Y, Wang J, Zhang Y, Yuan W, Du J, Shi Z, Ma J, Zhang J, Zhang X, Wang X
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum.
Wang L, Zhu Z, Liao Y, Zhang L, Yu Z, Yang R, Wu J, Wu Z, Sun X
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2092-2107
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2092-2107
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Cui L, Li J, Guan S, Zhang K, Zhang K, Li J
Materials today. Bio 2022 Mar;14:100257
Materials today. Bio 2022 Mar;14:100257
The serum soluble Klotho alleviates cardiac aging and regulates M2a/M2c macrophage polarization via inhibiting TLR4/Myd88/NF-κB pathway.
Wang Y, Wang K, Bao Y, Zhang T, Ainiwaer D, Xiong X, Wang G, Sun Z
Tissue & cell 2022 Jun;76:101812
Tissue & cell 2022 Jun;76:101812
Effect of metformin in autistic BTBR T + Itpr3tf/J mice administered a high-fat diet.
Deng W, Li F, Ke H, Wang S, Li Z, Lv P, Chen Y
Brain research bulletin 2022 Jun 1;183:172-183
Brain research bulletin 2022 Jun 1;183:172-183
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Wang Y, Xie W, Feng Y, Xu Z, He Y, Xiong Y, Chen L, Li X, Liu J, Liu G, Wu Q
International journal of molecular medicine 2022 Jul;50(1)
International journal of molecular medicine 2022 Jul;50(1)
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Li T, Bai J, Du Y, Tan P, Zheng T, Chen Y, Cheng Y, Cai T, Huang M, Fu W, Wen J
International immunopharmacology 2022 Jul;108:108892
International immunopharmacology 2022 Jul;108:108892
Sensory nerves promote corneal inflammation resolution via CGRP mediated transformation of macrophages to the M2 phenotype through the PI3K/AKT signaling pathway.
Yuan K, Zheng J, Shen X, Wu Y, Han Y, Jin X, Huang X
International immunopharmacology 2022 Jan;102:108426
International immunopharmacology 2022 Jan;102:108426
Decreased Monocyte Count Is Associated With Gestational Diabetes Mellitus Development, Macrosomia, and Inflammation.
Huang X, Zha B, Zhang M, Li Y, Wu Y, Zhang R, Sheng L, Xu J, Yu Z, Gao C, Chen Z, Ding H, Ma L, Zhang Y, Zang S, Zhang TN, Liu J
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
The Journal of clinical endocrinology and metabolism 2022 Jan 1;107(1):192-204
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis.
Chen Z, Hao W, Gao C, Zhou Y, Zhang C, Zhang J, Wang R, Wang Y, Wang S
Acta pharmaceutica Sinica. B 2022 Aug;12(8):3367-3382
Acta pharmaceutica Sinica. B 2022 Aug;12(8):3367-3382
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Pei Z, Ma L, Li Y, Yang J, Yang Q, Yao W, Li S
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Itai Y, Ueda Y, Etoh T, Shirasaka Y, Shiroshita H, Shiraishi N, Daa T, Inomata M
Journal of surgical oncology 2021 Sep;124(3):293-300
Journal of surgical oncology 2021 Sep;124(3):293-300
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
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DNA and cell biology 2016 Dec;35(12):853-860
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 60269-1-Ig( IL10 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL-10 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human IL-10. This antibody recognizes human antigen. The IL-10 antibody has been validated for the following applications: ELISA, WB analysis.
