Tissue expression
Cell line expression
Protein structure

IL10

Interleukin 10
CSIF, IL-10, IL10A, TGIF 
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
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1806 antibodies from 47 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
37 antibodies
Invitrogen Antibodies
74 antibodies
R&D Systems
55 antibodies
Novus Biologicals
112 antibodies
Proteintech Group
4 antibodies
antibodies-online
440 antibodies
OriGene
41 antibodies
Biorbyt
142 antibodies
Aviva Systems Biology
20 antibodies
BioLegend
37 antibodies
Acris Antibodies GmbH
44 antibodies
NSJ Bioreagents
10 antibodies
Affinity Biosciences
2 antibodies
Abgent
8 antibodies
St John's Laboratory
26 antibodies
Boster Biological Technology
7 antibodies
NovoPro Bioscience Inc.
9 antibodies
Wuhan Fine Biotech Co., Ltd.
2 antibodies
Cusabio Biotech Co., Ltd
3 antibodies
Abbiotec
2 antibodies
Abnova Corporation
21 antibodies
ProSci
10 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
PeproTech Inc.
17 antibodies
RabMAbs
4 antibodies
Cell Signaling Technology, Inc
2 antibodies
Absolute Antibody
8 antibodies
MyBioSource
21 antibodies
Creative Diagnostics
28 antibodies
GenWay
23 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
Creative Biolabs
120 antibodies
SICGEN
1 antibody
Miltenyi Biotec
25 antibodies
United States Biological
82 antibodies
Abbexa
13 antibodies
EMD Millipore
3 antibodies
Exalpha Biologicals, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
Kerafast Inc.
5 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
Leading Biology
5 antibodies
eBioscience, An Affymetrix Company
19 antibodies