IL10

gene product
CSIF, IL-10, IL10A, TGIF
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2011]
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1597 antibodies from 42 providers.

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GeneTex
37 antibodies
R&D Systems
54 antibodies
Novus Biologicals
110 antibodies
antibodies-online
440 antibodies
Boster Biological Technology
6 antibodies
Biorbyt
99 antibodies
Aviva Systems Biology
20 antibodies
OriGene
35 antibodies
BioLegend
37 antibodies
Acris Antibodies GmbH
44 antibodies
LifeSpan BioSciences, Inc.
248 antibodies
NSJ Bioreagents
9 antibodies
Affinity Biosciences
2 antibodies
Abgent
8 antibodies
Invitrogen Antibodies
35 antibodies
NovoPro Bioscience Inc.
9 antibodies
Abbiotec
2 antibodies
Abnova Corporation
21 antibodies
ProSci
10 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
3 antibodies
St John's Laboratory
4 antibodies
Proteintech Group
2 antibodies
RabMAbs
4 antibodies
Cell Signaling Technology, Inc
2 antibodies
Creative Biolabs
106 antibodies
Absolute Antibody
8 antibodies
MyBioSource
21 antibodies
Creative Diagnostics
28 antibodies
GenWay
23 antibodies
SICGEN
1 antibody
Miltenyi Biotec
25 antibodies
United States Biological
82 antibodies
Exalpha Biologicals, Inc.
5 antibodies
PeproTech Inc.
3 antibodies
EMD Millipore
3 antibodies
RayBiotech, Inc.
1 antibody
eBioscience, An Affymetrix Company
19 antibodies
Sigma-Aldrich
4 antibodies