Antibody data
- Antibody Data
 - Antigen structure
 - References [1]
 - Comments [0]
 - Validations [0]
 
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- Product number
 - 501406 - Provider product page

 - Provider
 - BioLegend
 - Proper citation
 - BioLegend Cat#501406, RRID:AB_315172
 - Product name
 - LEAF™ Purified anti-human IL-10 [JES3-9D7]
 - Antibody type
 - Monoclonal
 - Antigen
 - COS - expressed, recombinant human IL-10
 - Description
 - IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production. The JES3-9D7 antibody reacts with human and viral interleukin-10 (IL-10).
 - Reactivity
 - Human, Simian
 - Host
 - Rat
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 50 µg
 - Concentration
 - 1 mg/ml
 - Storage
 - The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
 
Submitted references		Glucocorticosteroids modify Langerhans cells to produce TGF-β and expand regulatory T cells.
				
		
	
			Stary G, Klein I, Bauer W, Koszik F, Reininger B, Kohlhofer S, Gruber K, Skvara H, Jung T, Stingl G
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):103-12
		Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 1;186(1):103-12
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