Antibody data
- Antibody Data
- Antigen structure
- References [112]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- 20850-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IL-10 antibody
- Antibody type
- Polyclonal
- Description
- IL-10 antibody (Cat. #20850-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure.
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
Bilirubin/morin self-assembled nanoparticle-engulfed collagen/polyvinyl alcohol hydrogel accelerates chronic diabetic wound healing by modulating inflammation and ameliorating oxidative stress.
X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity.
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
PPM1G regulates hepatic ischemia/reperfusion injury through STING-mediated inflammatory pathways in macrophages.
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway.
Role of iron in host-microbiota interaction and its effects on intestinal mucosal growth and immune plasticity in a piglet model.
Electroacupuncture alleviates postoperative pain through inhibiting neuroinflammation via stimulator of interferon genes/type-1 interferon pathway.
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.
Tetrandrine attenuates SNI-induced mechanical allodynia by inhibiting spinal CKLF1.
Bio-inspired glycosylated nano-hydroxyapatites enhance endogenous bone regeneration by modulating macrophage M2 polarization.
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
In situ polyphenol-adhesive hydrogel enhanced the noncarcinogenic repairing of KGF on the gut epithelial barrier on TNBS-induced colitis rats.
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Gegen-Qinlian decoction alleviates anxiety-like behaviors in methamphetamine-withdrawn mice by regulating Akkermansia and metabolism in the colon.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Susceptibility of Fat Tissue to SARS-CoV-2 Infection in Female hACE2 Mouse Model.
Ultrasound-induced destruction of heparin-loaded microbubbles attenuates L-arginine-induced acute pancreatitis.
Therapeutic effect of Atractylenolide I on Aspergillus fumigatus keratitis by affecting MyD88/ NF-κB pathway and IL-1β, IL-10 expression.
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy.
The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Sex Differences in Cardiac Pathology of SARS-CoV2 Infected and Trypanosoma cruzi Co-infected Mice.
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Transcriptome-Based Dissection of Intracranial Aneurysms Unveils an "Immuno-Thermal" Microenvironment and Defines a Pathological Feature-Derived Gene Signature for Risk Estimation.
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Drawn-on-Skin Sensors from Fully Biocompatible Inks toward High-Quality Electrophysiology.
In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot.
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn's disease.
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury.
Lactobacillus salivarius UCC118™ Dampens Inflammation and Promotes Microbiota Recovery to Provide Therapeutic Benefit in a DSS-Induced Colitis Model.
Intestinal dysbacteriosis-propelled T helper 17 cells activation mediate the perioperative neurocognitive disorder induced by anesthesia/surgery in aged rats.
Non-mitogenic fibroblast growth factor 1 protects against ischemic stroke by regulating microglia/macrophage polarization through Nrf2 and NF-κB pathways.
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling.
Skin-adaptive film dressing with smart-release of growth factors accelerated diabetic wound healing.
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
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The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
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Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice.
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Loss of Lymphotoxin Alpha-Expressing Memory B Cells Correlates with Metastasis of Human Primary Melanoma.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
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The role of IP-10 and its receptor CXCR3 in early pregnancy.
In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis.
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke.
DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Vagus Nerve Stimulation Transiently Mitigates Chemotherapy-Induced Peripheral Neuropathy in Rats.
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
IL-10 Restores MHC Class I Expression and Interferes With Immunity in Papillary Thyroid Cancer With Hashimoto Thyroiditis.
IFI30 expression is an independent unfavourable prognostic factor in glioma.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
IL-10 suppresses IFN-γ-mediated signaling in lung adenocarcinoma.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages.
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.
Protective effect of Xin-Ji-Er-Kang on cardiovascular remodeling in high salt-induced hypertensive mice.
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Macrophage polarization in human gingival tissue in response to periodontal disease.
Extracellular vesicles from human umbilical cord mesenchymal stem cells improve nerve regeneration after sciatic nerve transection in rats.
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Correlative analysis of the expression of IL-10 and Ki-67 in human cervical cancer and cervical intraepithelial neoplasias and human papillomavirus infection.
TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway.
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Diffuse large B cell lymphoma associated with chronic inflammation arising within atrial myxoma: aggressive histological features but indolent clinical behaviour.
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Effect of IL-17 in the development of colon cancer in mice.
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Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
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Bilirubin/morin self-assembled nanoparticle-engulfed collagen/polyvinyl alcohol hydrogel accelerates chronic diabetic wound healing by modulating inflammation and ameliorating oxidative stress.
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International journal of biological macromolecules 2024 Mar;261(Pt 1):129704
International journal of biological macromolecules 2024 Mar;261(Pt 1):129704
X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity.
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Genes & diseases 2024 Mar;11(2):935-951
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
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Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
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Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
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International immunopharmacology 2024 Jan 25;127:111423
PPM1G regulates hepatic ischemia/reperfusion injury through STING-mediated inflammatory pathways in macrophages.
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Phthalate exposure aggravates periodontitis by activating NFκB pathway.
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Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway.
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Electroacupuncture alleviates postoperative pain through inhibiting neuroinflammation via stimulator of interferon genes/type-1 interferon pathway.
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Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
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Tetrandrine attenuates SNI-induced mechanical allodynia by inhibiting spinal CKLF1.
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Neuropharmacology 2023 Nov 1;238:109673
Bio-inspired glycosylated nano-hydroxyapatites enhance endogenous bone regeneration by modulating macrophage M2 polarization.
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Acta biomaterialia 2023 May;162:135-148
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Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
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In situ polyphenol-adhesive hydrogel enhanced the noncarcinogenic repairing of KGF on the gut epithelial barrier on TNBS-induced colitis rats.
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International journal of biological macromolecules 2023 Mar 15;231:123323
International journal of biological macromolecules 2023 Mar 15;231:123323
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
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Journal of liposome research 2023 Jun;33(2):144-153
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
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International journal of molecular sciences 2023 Jan 9;24(2)
Ultrasound-induced destruction of heparin-loaded microbubbles attenuates L-arginine-induced acute pancreatitis.
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Jan 1;180:106318
Therapeutic effect of Atractylenolide I on Aspergillus fumigatus keratitis by affecting MyD88/ NF-κB pathway and IL-1β, IL-10 expression.
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Cytokine 2023 Feb;162:156112
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
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Acta biomaterialia 2023 Feb;157:467-486
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The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
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Anaerobe 2023 Aug;82:102768
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
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International urology and nephrology 2023 Aug;55(8):1957-1970
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
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CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
Sex Differences in Cardiac Pathology of SARS-CoV2 Infected and Trypanosoma cruzi Co-infected Mice.
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Frontiers in cardiovascular medicine 2022;9:783974
Frontiers in cardiovascular medicine 2022;9:783974
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Frontiers in nutrition 2022;9:1028459
Frontiers in nutrition 2022;9:1028459
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
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Mediators of inflammation 2022;2022:2579003
Mediators of inflammation 2022;2022:2579003
Transcriptome-Based Dissection of Intracranial Aneurysms Unveils an "Immuno-Thermal" Microenvironment and Defines a Pathological Feature-Derived Gene Signature for Risk Estimation.
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Frontiers in immunology 2022;13:878195
Frontiers in immunology 2022;13:878195
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
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Frontiers in microbiology 2022;13:818111
Frontiers in microbiology 2022;13:818111
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
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Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
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Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2107099
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2107099
In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot.
Zhao Y, Luo L, Huang L, Zhang Y, Tong M, Pan H, Shangguan J, Yao Q, Xu S, Xu H
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:93-106
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:93-106
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Ramani K, Mavila N, Abeynayake A, Tomasi ML, Wang J, Matsuda M, Seki E
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn's disease.
Shen Z, Luo W, Tan B, Nie K, Deng M, Wu S, Xiao M, Wu X, Meng X, Tong T, Zhang C, Ma K, Liao Y, Xu J, Wang X
EBioMedicine 2022 Nov;85:104285
EBioMedicine 2022 Nov;85:104285
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Han Y, Yao R, Yang Z, Li S, Meng W, Zhang Y, Zhang Y, Luo H
Experimental cell research 2022 Mar 1;412(1):113002
Experimental cell research 2022 Mar 1;412(1):113002
DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury.
Zhao N, Li Y, Wang C, Xue Y, Peng L, Wang T, Zhao Y, Xu G, Yu S
Neurochemistry international 2022 Jul;157:105341
Neurochemistry international 2022 Jul;157:105341
Lactobacillus salivarius UCC118™ Dampens Inflammation and Promotes Microbiota Recovery to Provide Therapeutic Benefit in a DSS-Induced Colitis Model.
Iyer N, Williams MA, O'Callaghan AA, Dempsey E, Cabrera-Rubio R, Raverdeau M, Crispie F, Cotter PD, Corr SC
Microorganisms 2022 Jul 9;10(7)
Microorganisms 2022 Jul 9;10(7)
Intestinal dysbacteriosis-propelled T helper 17 cells activation mediate the perioperative neurocognitive disorder induced by anesthesia/surgery in aged rats.
Wen Y, Feng S, Dai H, Mao M, Zhou Z, Li B, Wang C, Cai X, Li S, Yang J, Ren Q, Sun J
Neuroscience letters 2022 Jul 13;783:136741
Neuroscience letters 2022 Jul 13;783:136741
Non-mitogenic fibroblast growth factor 1 protects against ischemic stroke by regulating microglia/macrophage polarization through Nrf2 and NF-κB pathways.
Dordoe C, Wang X, Lin P, Wang Z, Hu J, Wang D, Fang Y, Liang F, Ye S, Chen J, Zhao Y, Xiong Y, Yang Y, Lin L, Li X
Neuropharmacology 2022 Jul 1;212:109064
Neuropharmacology 2022 Jul 1;212:109064
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Wu L, Li S, Li C, He B, Lv L, Wang J, Wang J, Wang W, Zhang Y
Chemico-biological interactions 2022 Jan 5;351:109740
Chemico-biological interactions 2022 Jan 5;351:109740
Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis.
Wang W, Sheng L, Chen Y, Li Z, Wu H, Ma J, Zhang D, Chen X, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153886
Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling.
Tu Q, Li Y, Zhu J, Guo L, Liu C, Liu L, Yuan Y, Zou Y, Chen F, Yao L, Li J
Cell proliferation 2022 Dec;55(12):e13328
Cell proliferation 2022 Dec;55(12):e13328
Skin-adaptive film dressing with smart-release of growth factors accelerated diabetic wound healing.
Zhao Y, Huang L, Lin G, Tong M, Xie Y, Pan H, Shangguan J, Yao Q, Xu S, Xu H
International journal of biological macromolecules 2022 Dec 1;222(Pt B):2729-2743
International journal of biological macromolecules 2022 Dec 1;222(Pt B):2729-2743
A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.
Zhao Y, Xue P, Lin G, Tong M, Yang J, Zhang Y, Ran K, Zhuge D, Yao Q, Xu H
Acta biomaterialia 2022 Apr 15;143:233-252
Acta biomaterialia 2022 Apr 15;143:233-252
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Wu M, Cong Y, Wang K, Yu H, Zhang X, Ma M, Duan Z, Pei X
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
PAK1 Silencing Attenuated Proinflammatory Macrophage Activation and Foam Cell Formation by Increasing PPARγ Expression.
Cheng WL, Zhang Q, Li B, Cao JL, Jiao L, Chao SP, Lu Z, Zhao F
Oxidative medicine and cellular longevity 2021;2021:6957900
Oxidative medicine and cellular longevity 2021;2021:6957900
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats.
Chen H, Yu B, Guo X, Hua H, Cui F, Guan Y, Tian Y, Zhang X, Zhang Y, Ma H
Frontiers in physiology 2021;12:639454
Frontiers in physiology 2021;12:639454
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Xu J, Tang Z, He Y, Cai S, Wang B, Zhang S, Wu M, Qian K, Zhang K, Chai B, Chen G, Xu K, Ji H, Xiao J, Wu Y
Frontiers in pharmacology 2021;12:628950
Frontiers in pharmacology 2021;12:628950
Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for treatment of moderate traumatic brain injury.
Li J, Zhang D, Guo S, Zhao C, Wang L, Ma S, Guan F, Yao M
International journal of biological macromolecules 2021 Sep 30;187:200-213
International journal of biological macromolecules 2021 Sep 30;187:200-213
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Chemical structure and anti-inflammatory activity of a branched polysaccharide isolated from Phellinus baumii.
Sun Y, Huo J, Zhong S, Zhu J, Li Y, Li X
Carbohydrate polymers 2021 Sep 15;268:118214
Carbohydrate polymers 2021 Sep 15;268:118214
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
The effects of BMMSC treatment on lung tissue degeneration in elderly macaques.
Yang YK, Li Y, Wang YY, Ruan GP, Tian C, Wang Q, He HY, Zhu GH, Fang D, Wang M, Zhu XQ, Pan XH
Stem cell research & therapy 2021 Mar 1;12(1):156
Stem cell research & therapy 2021 Mar 1;12(1):156
Attenuation of Inflammation by DJ-1 May Be a Drug Target for Cerebral Ischemia-Reperfusion Injury.
Zhao N, Wang T, Peng L, Li Y, Zhao Y, Yu S
Neurochemical research 2021 Jun;46(6):1470-1479
Neurochemical research 2021 Jun;46(6):1470-1479
Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice.
Zheng H, Xu P, Jiang Q, Xu Q, Zheng Y, Yan J, Ji H, Ning J, Zhang X, Li C, Zhang L, Li Y, Li X, Song W, Gao H
Microbiome 2021 Jun 25;9(1):145
Microbiome 2021 Jun 25;9(1):145
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.
Ahmad KA, Shoaib RM, Ahsan MZ, Deng MY, Ma L, Apryani E, Li XY, Wang YX
Brain, behavior, and immunity 2021 Jul;95:344-361
Brain, behavior, and immunity 2021 Jul;95:344-361
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Loss of Lymphotoxin Alpha-Expressing Memory B Cells Correlates with Metastasis of Human Primary Melanoma.
Werner F, Wagner C, Simon M, Glatz K, Mertz KD, Läubli H, Richtig E, Griss J, Wagner SN
Diagnostics (Basel, Switzerland) 2021 Jul 12;11(7)
Diagnostics (Basel, Switzerland) 2021 Jul 12;11(7)
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Xu Q, Fan Y, Loor JJ, Liang Y, Lv H, Sun X, Jia H, Xu C
Food & function 2021 Jan 21;12(2):696-705
Food & function 2021 Jan 21;12(2):696-705
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
Dual-targeting tumor cells and tumor associated macrophages with lipid coated calcium zoledronate for enhanced lung cancer chemoimmunotherapy.
Zang X, Zhou J, Zhang X, Chen D, Han Y, Chen X
International journal of pharmaceutics 2021 Feb 1;594:120174
International journal of pharmaceutics 2021 Feb 1;594:120174
The role of IP-10 and its receptor CXCR3 in early pregnancy.
Jiang Y, Huang F, Chai X, Yuan W, Ding H, Wu X
Molecular immunology 2021 Dec;140:59-69
Molecular immunology 2021 Dec;140:59-69
In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis.
Shao W, Chen R, Lin G, Ran K, Zhang Y, Yang J, Pan H, Shangguan J, Zhao Y, Xu H
Biomaterials science 2021 Dec 21;10(1):227-242
Biomaterials science 2021 Dec 21;10(1):227-242
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Hong Y, Zhou Y, Shen L, Wei Y, Long C, Fu Y, Wu H, Wang J, Wu Y, Wu S, Wei G
Ecotoxicology and environmental safety 2021 Dec 20;227:112889
Ecotoxicology and environmental safety 2021 Dec 20;227:112889
CIHH protects the heart against left ventricular remodelling and myocardial fibrosis by balancing the renin-angiotensin system in SHR.
Yu B, Chen H, Guo XQ, Hua H, Guan Y, Cui F, Tian YM, Zhang HX, Zhang XJ, Zhang Y, Ma HJ
Life sciences 2021 Aug 1;278:119540
Life sciences 2021 Aug 1;278:119540
High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke.
Hu M, Lin Y, Men X, Wang S, Sun X, Zhu Q, Lu D, Liu S, Zhang B, Cai W, Lu Z
Journal of neuroinflammation 2021 Apr 12;18(1):90
Journal of neuroinflammation 2021 Apr 12;18(1):90
DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion.
Wang T, Zhao N, Peng L, Li Y, Huang X, Zhu J, Chen Y, Yu S, Zhao Y
Frontiers in cell and developmental biology 2020;8:593890
Frontiers in cell and developmental biology 2020;8:593890
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Vagus Nerve Stimulation Transiently Mitigates Chemotherapy-Induced Peripheral Neuropathy in Rats.
Zhang R, Gan Y, Li J, Feng Y
Journal of pain research 2020;13:3457-3465
Journal of pain research 2020;13:3457-3465
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Zhang S, Zhang H, Jin Z, Wang S, Wang Y, Zhu L, Sun W, Yan B
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Journal of cellular physiology 2020 Sep;235(9):5938-5950
IL-10 Restores MHC Class I Expression and Interferes With Immunity in Papillary Thyroid Cancer With Hashimoto Thyroiditis.
Lu ZW, Hu JQ, Liu WL, Wen D, Wei WJ, Wang YL, Wang Y, Liao T, Ji QH
Endocrinology 2020 Oct 1;161(10)
Endocrinology 2020 Oct 1;161(10)
IFI30 expression is an independent unfavourable prognostic factor in glioma.
Liu X, Song C, Yang S, Ji Q, Chen F, Li W
Journal of cellular and molecular medicine 2020 Nov;24(21):12433-12443
Journal of cellular and molecular medicine 2020 Nov;24(21):12433-12443
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
IL-10 suppresses IFN-γ-mediated signaling in lung adenocarcinoma.
Gao Y, Lu J, Zeng C, Yang J, Huang B, Zhang N, Li L, Fu X
Clinical and experimental medicine 2020 Aug;20(3):449-459
Clinical and experimental medicine 2020 Aug;20(3):449-459
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages.
Wang D, Wang X, Si M, Yang J, Sun S, Wu H, Cui S, Qu X, Yu X
Cancer letters 2020 Apr 1;474:36-52
Cancer letters 2020 Apr 1;474:36-52
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Wang G, Xu B, Shi F, Du M, Li Y, Yu T, Chen L
Oxidative medicine and cellular longevity 2019;2019:7850324
Oxidative medicine and cellular longevity 2019;2019:7850324
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
Yang B, Figueroa DM, Hou Y, Babbar M, Baringer SL, Croteau DL, Bohr VA
Free radical biology & medicine 2019 Sep;141:47-58
Free radical biology & medicine 2019 Sep;141:47-58
B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.
Griss J, Bauer W, Wagner C, Simon M, Chen M, Grabmeier-Pfistershammer K, Maurer-Granofszky M, Roka F, Penz T, Bock C, Zhang G, Herlyn M, Glatz K, Läubli H, Mertz KD, Petzelbauer P, Wiesner T, Hartl M, Pickl WF, Somasundaram R, Steinberger P, Wagner SN
Nature communications 2019 Sep 13;10(1):4186
Nature communications 2019 Sep 13;10(1):4186
Protective effect of Xin-Ji-Er-Kang on cardiovascular remodeling in high salt-induced hypertensive mice.
Huang G, Cheng P, Ding L, Wang L, Hu J, Zhang Y, Cai G, Chen M, Shen A, Gao S
Experimental and therapeutic medicine 2019 Mar;17(3):1551-1562
Experimental and therapeutic medicine 2019 Mar;17(3):1551-1562
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Wang R, Dong Z, Lan X, Liao Z, Chen M
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, Grau GE, Zeng Z, Lu J, Zhou G, Xie L, Sun S
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Macrophage polarization in human gingival tissue in response to periodontal disease.
Zhou LN, Bi CS, Gao LN, An Y, Chen F, Chen FM
Oral diseases 2019 Jan;25(1):265-273
Oral diseases 2019 Jan;25(1):265-273
Extracellular vesicles from human umbilical cord mesenchymal stem cells improve nerve regeneration after sciatic nerve transection in rats.
Ma Y, Dong L, Zhou D, Li L, Zhang W, Zhen Y, Wang T, Su J, Chen D, Mao C, Wang X
Journal of cellular and molecular medicine 2019 Apr;23(4):2822-2835
Journal of cellular and molecular medicine 2019 Apr;23(4):2822-2835
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q
Medicine and science in sports and exercise 2018 May;50(5):945-956
Medicine and science in sports and exercise 2018 May;50(5):945-956
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Correlative analysis of the expression of IL-10 and Ki-67 in human cervical cancer and cervical intraepithelial neoplasias and human papillomavirus infection.
Min Z, Pu X, Gu Z
Oncology letters 2018 Dec;16(6):7189-7194
Oncology letters 2018 Dec;16(6):7189-7194
TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway.
Li R, Liu W, Yin J, Chen Y, Guo S, Fan H, Li X, Zhang X, He X, Duan C
Journal of neuroinflammation 2018 Aug 20;15(1):231
Journal of neuroinflammation 2018 Aug 20;15(1):231
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wu W, Wei W, Lu M, Zhu X, Liu N, Niu Y, Sun T, Li Y, Yu J
Neurochemical research 2017 Nov;42(11):3186-3198
Neurochemical research 2017 Nov;42(11):3186-3198
Diffuse large B cell lymphoma associated with chronic inflammation arising within atrial myxoma: aggressive histological features but indolent clinical behaviour.
Yan J, Luo D, Zhang F, He J, Yao S, Luo X, Xu F, Chen Y, Fu L, Xu J, Liu Y
Histopathology 2017 Dec;71(6):951-959
Histopathology 2017 Dec;71(6):951-959
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Xu Q, Fu R, Yin G, Liu X, Liu Y, Xiang M
Gene 2016 Mar 10;578(2):263-73
Gene 2016 Mar 10;578(2):263-73
Effect of IL-17 in the development of colon cancer in mice.
Yang L, Liu H, Zhang L, Hu J, Chen H, Wang L, Yin X, Li Q, Qi Y
Oncology letters 2016 Dec;12(6):4929-4936
Oncology letters 2016 Dec;12(6):4929-4936
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 20850-1-AP( IL10 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL-10 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IL-10. This antibody recognizes human antigen. The IL-10 antibody has been validated for the following applications: ELISA, WB analysis.