MAB7351

antibody from R&D Systems

Targeting: IL10 CSIF, IL-10, IL10A, TGIF

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB7351

Provider

R&D Systems

Product name

Canine IL-10 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Delects canine IL-10 in ELISAs. In ELISAs, this antibody does not cross-react with recombinant feline IL-10, recombinant human (rh) IL-10, recombinant mouse (rm) IL-10, recombinant porcine IL-10, rhIL-10 sR, rmIL-10 sR, or recombinant rat IL-10.

Reactivity

Canine

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

XP_855560


Isotype

IgG

Antibody clone number

138111

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.

Roatt BM, Aguiar-Soares RD, Reis LE, Cardoso JM, Mathias FA, de Brito RC, da Silva SM, Gontijo NF, Ferreira SA, Valenzuela JG, Corrêa-Oliveira R, Giunchetti RC, Reis AB
Frontiers in immunology 2017;8:217

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Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs.

Petitdidier E, Pagniez J, Papierok G, Vincendeau P, Lemesre JL, Bras-Gonçalves R
PLoS neglected tropical diseases 2016 May;10(5):e0004614

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Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function.

Esch KJ, Juelsgaard R, Martinez PA, Jones DE, Petersen CA
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5542-50

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Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs.

Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM
Vaccine 2006 Jan 23;24(4):501-9