MAB2171

antibody from R&D Systems

Targeting: IL10 CSIF, IL-10, IL10A, TGIF

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB2171

Provider

R&D Systems

Product name

Anti-Human IL-10 Monoclonal Antibody (Clone 25209)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human IL-10, Ser19-Asn178

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P22301


Isotype

IgG

Vial size

500 µg

References

Submitted references

Oral fibroblasts modulate the macrophage response to bacterial challenge.

Tzach-Nahman R, Nashef R, Fleissig O, Palmon A, Shapira L, Wilensky A, Nussbaum G
Scientific reports 2017 Sep 14;7(1):11516

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Interleukin-10-producing LAG3⁺ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.

Nakachi S, Sumitomo S, Tsuchida Y, Tsuchiya H, Kono M, Kato R, Sakurai K, Hanata N, Nagafuchi Y, Tateishi S, Kanda H, Okamura T, Yamamoto K, Fujio K
Arthritis research & therapy 2017 May 16;19(1):97

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S100A8/A9 mRNA induction in an ex vivo model of endotoxin tolerance: roles of IL-10 and IFNγ.

Fontaine M, Planel S, Peronnet E, Turrel-Davin F, Piriou V, Pachot A, Monneret G, Lepape A, Venet F
PloS one 2014;9(6):e100909

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HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms.

Planès R, BenMohamed L, Leghmari K, Delobel P, Izopet J, Bahraoui E
Journal of virology 2014 Jun;88(12):6672-89

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IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses.

Svajger U, Obermajer N, Jeras M
Journal of leukocyte biology 2014 Jan;95(1):33-46

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Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

Nicolaidou V, Wong MM, Redpath AN, Ersek A, Baban DF, Williams LM, Cope AP, Horwood NJ
PloS one 2012;7(7):e39871

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DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function.

Svajger U, Obermajer N, Anderluh M, Kos J, Jeras M
Journal of leukocyte biology 2011 Jun;89(6):893-905

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Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.

Tran DQ, Glass DD, Uzel G, Darnell DA, Spalding C, Holland SM, Shevach EM
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2929-38

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Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.

Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
European journal of immunology 2008 Apr;38(4):1012-23

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Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo.

Hajishengallis G, Shakhatreh MA, Wang M, Liang S
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 15;179(4):2359-67

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Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo.

Hajishengallis G, Shakhatreh MA, Wang M, Liang S
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 15;179(4):2359-67

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Effect of IL-21 on NK cells derived from different umbilical cord blood populations.

Perez SA, Mahaira LG, Sotiropoulou PA, Gritzapis AD, Iliopoulou EG, Niarchos DK, Cacoullos NT, Kavalakis YG, Antsaklis AI, Sotiriadou NN, Baxevanis CN, Papamichail M
International immunology 2006 Jan;18(1):49-58