Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10254-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10254-2-AP, RRID:AB_2263577
- Product name
- GRB2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GRB2 antibody (Cat. #10254-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Screening and Verification of Key Ubiquitination Genes Related to Immune Infiltration in Stage III/IV Hepatocellular Carcinoma.
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis.
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.
Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2.
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Melittin inhibits tumor growth and decreases resistance to gemcitabine by downregulating cholesterol pathway gene CLU in pancreatic ductal adenocarcinoma.
iTRAQ-based Proteomic Analysis of Porcine Kidney Epithelial PK15 cells Infected with Pseudorabies virus.
mir-329 restricts tumor growth by targeting grb2 in pancreatic cancer.
Tang Y, Cao J, Peng R, Mao X, Su B, Tang H, Tu D, Zhou J, Jiang G, Jin S, Wang Q, Zhang C, Liu R, Zhang C, Bai D
Journal of hepatocellular carcinoma 2023;10:765-781
Journal of hepatocellular carcinoma 2023;10:765-781
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Fang J, Zhang Y, Huang C, Lu R, Yu J, Chen R, Wang Y, Zhao X, Yu J, Huang J
Oncogene 2023 Mar;42(14):1058-1071
Oncogene 2023 Mar;42(14):1058-1071
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
Jin ML, Gong Y, Ji P, Hu X, Shao ZM
Cancer science 2023 Jun;114(6):2375-2385
Cancer science 2023 Jun;114(6):2375-2385
HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis.
Jiang Q, Zhang D, Liu J, Liang C, Yang R, Zhang C, Wu J, Lin J, Ye T, Ding L, Li J, Gao S, Li B, Ye Q
Science advances 2023 Jun 9;9(23):eade1155
Science advances 2023 Jun 9;9(23):eade1155
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Pang H, Lei D, Huang J, Guo Y, Fan C
Molecular and cellular probes 2023 Feb;67:101896
Molecular and cellular probes 2023 Feb;67:101896
Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.
Chu H, Zhao Q, Liu J, Yang K, Wang Y, Liu J, Zhang K, Zhao B, He H, Zheng Y, Zhong S, Liang Z, Zhang L, Zhang Y
Analytical chemistry 2022 Jan 18;94(2):758-767
Analytical chemistry 2022 Jan 18;94(2):758-767
Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2.
Lv J, Zhang S, Wu H, Lu J, Lu Y, Wang F, Zhao W, Zhan P, Lu J, Fang Q, Xie C, Yin Z
Cancer letters 2020 Jan 28;469:22-34
Cancer letters 2020 Jan 28;469:22-34
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway.
Meng L, Liu S, Liu F, Sang M, Ju Y, Fan X, Gu L, Li Z, Geng C, Sang M
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
Molecular therapy. Nucleic acids 2020 Aug 19;22:124-137
MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth.
Zhu JF, Liu Y, Huang H, Shan L, Han ZG, Liu JY, Li YL, Dong X, Zeng W
Cancer cell international 2018;18:193
Cancer cell international 2018;18:193
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Hou L, Gu W, Zhu H, Yao W, Wang W, Meng Q
Molecular immunology 2017 Nov;91:75-85
Molecular immunology 2017 Nov;91:75-85
Melittin inhibits tumor growth and decreases resistance to gemcitabine by downregulating cholesterol pathway gene CLU in pancreatic ductal adenocarcinoma.
Wang X, Xie J, Lu X, Li H, Wen C, Huo Z, Xie J, Shi M, Tang X, Chen H, Peng C, Fang Y, Deng X, Shen B
Cancer letters 2017 Jul 28;399:1-9
Cancer letters 2017 Jul 28;399:1-9
iTRAQ-based Proteomic Analysis of Porcine Kidney Epithelial PK15 cells Infected with Pseudorabies virus.
Yang S, Pei Y, Zhao A
Scientific reports 2017 Apr 4;7:45922
Scientific reports 2017 Apr 4;7:45922
mir-329 restricts tumor growth by targeting grb2 in pancreatic cancer.
Wang X, Lu X, Zhang T, Wen C, Shi M, Tang X, Chen H, Peng C, Li H, Fang Y, Deng X, Shen B
Oncotarget 2016 Apr 19;7(16):21441-53
Oncotarget 2016 Apr 19;7(16):21441-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GRB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GRB2. This antibody recognizes human,mouse,rat antigen. The GRB2 antibody has been validated for the following applications: ELISA, WB analysis.