Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PAB14689 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB14689, RRID:AB_10680504
- Product name
- GRB2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of GRB2.
- Storage
- Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Submitted references Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.
SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases.
GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation.
den Hertog J, Hunter T
The EMBO journal 1996 Jun 17;15(12):3016-27
The EMBO journal 1996 Jun 17;15(12):3016-27
SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases.
Reif K, Buday L, Downward J, Cantrell DA
The Journal of biological chemistry 1994 May 13;269(19):14081-7
The Journal of biological chemistry 1994 May 13;269(19):14081-7
GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation.
Sieh M, Batzer A, Schlessinger J, Weiss A
Molecular and cellular biology 1994 Jul;14(7):4435-42
Molecular and cellular biology 1994 Jul;14(7):4435-42
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western Blotting analysis (reducing conditions) of Ramos cell lysate using GRB2 polyclonal antibody (Cat # PAB14689).