Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- Ab106387 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- GRB2 Mouse mAb
- Antibody type
- Monoclonal
- Description
- Mouse anti Human GRB2 Antibody, Monoclonal (5G3-E7-F11), could be used for WB and so on .Application:WB: 1/500-1/1000Protein FunctionAdapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
AA 1-217
- Antibody clone number
- 5G3-E7-F11
- Vial size
- 100_l,10_l,1ml,50_l
- Concentration
- 4,2 mg/ml
- Storage
- Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- GRB2 Mouse mAb (Ab106387) - Western Blot All lanes: GRB2 Mouse mAb (Ab106387) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040)at 1/20000 dilution Predicted band size: 25 kDa Observed band size: 25 kDa Exposure time: 7.2 s