Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- NBP2-27149PE - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TLR4 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. The amino acid sequence used has 100% identity in human, chimp, baboon, chinese hamster, and rat
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
Submitted references Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation.
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression.
Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats.
Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function.
Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus.
CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer.
Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine.
The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in epithelial cells.
Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice.
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils.
Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease.
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells.
In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes.
Degraaf AJ, Zasłona Z, Bourdonnay E, Peters-Golden M
American journal of respiratory cell and molecular biology 2014 Aug;51(2):242-50
American journal of respiratory cell and molecular biology 2014 Aug;51(2):242-50
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Abdi J, Mutis T, Garssen J, Redegeld F
PloS one 2013;8(4):e60671
PloS one 2013;8(4):e60671
Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression.
Semar S, Klotz M, Letiembre M, Van Ginneken C, Braun A, Jost V, Bischof M, Lammers WJ, Liu Y, Fassbender K, Wyss-Coray T, Kirchhoff F, Schäfer KH
Journal of Alzheimer's disease : JAD 2013;36(1):7-20
Journal of Alzheimer's disease : JAD 2013;36(1):7-20
Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats.
Jazaeri F, Tavangar SM, Ghazi-Khansari M, Khorramizadeh MR, Mani AR, Dehpour AR
Liver international : official journal of the International Association for the Study of the Liver 2013 Mar;33(3):368-74
Liver international : official journal of the International Association for the Study of the Liver 2013 Mar;33(3):368-74
Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function.
McCulloch L, Brown KL, Mabbott NA
Immunology 2013 Mar;138(3):246-57
Immunology 2013 Mar;138(3):246-57
Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus.
Janardhanam SB, Prakasam S, Swaminathan VT, Kodumudi KN, Zunt SL, Srinivasan M
Archives of oral biology 2012 May;57(5):495-502
Archives of oral biology 2012 May;57(5):495-502
CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer.
Zheng YX, Yang M, Rong TT, Yuan XL, Ma YH, Wang ZH, Shen LS, Cui L
World journal of gastroenterology 2012 May 14;18(18):2253-61
World journal of gastroenterology 2012 May 14;18(18):2253-61
Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine.
Liu Y, Fatheree NY, Mangalat N, Rhoads JM
American journal of physiology. Gastrointestinal and liver physiology 2012 Mar 15;302(6):G608-17
American journal of physiology. Gastrointestinal and liver physiology 2012 Mar 15;302(6):G608-17
The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in epithelial cells.
Hafez M, Hayes K, Goldrick M, Grencis RK, Roberts IS
Infection and immunity 2010 May;78(5):2153-62
Infection and immunity 2010 May;78(5):2153-62
Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice.
Johnston MJ, Wang A, Catarino ME, Ball L, Phan VC, MacDonald JA, McKay DM
Infection and immunity 2010 Mar;78(3):1364-75
Infection and immunity 2010 Mar;78(3):1364-75
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF
Immunology 2010 Mar;129(3):363-74
Immunology 2010 Mar;129(3):363-74
Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils.
Worku M, Morris A
Journal of dairy science 2009 Jul;92(7):3185-93
Journal of dairy science 2009 Jul;92(7):3185-93
Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease.
Lunardi C, Bason C, Dolcino M, Navone R, Simone R, Saverino D, Frulloni L, Tinazzi E, Peterlana D, Corrocher R, Puccetti A
Journal of internal medicine 2009 Feb;265(2):250-65
Journal of internal medicine 2009 Feb;265(2):250-65
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
Cohen PA, Koski GK, Czerniecki BJ, Bunting KD, Fu XY, Wang Z, Zhang WJ, Carter CS, Awad M, Distel CA, Nagem H, Paustian CC, Johnson TD, Tisdale JF, Shu S
Blood 2008 Sep 1;112(5):1832-43
Blood 2008 Sep 1;112(5):1832-43
Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells.
Allam JP, Peng WM, Appel T, Wenghoefer M, Niederhagen B, Bieber T, Bergé S, Novak N
The Journal of allergy and clinical immunology 2008 Feb;121(2):368-374.e1
The Journal of allergy and clinical immunology 2008 Feb;121(2):368-374.e1
In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes.
Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, Beri R, Dolcino M, Valletta E, Corrocher R, Puccetti A
PLoS medicine 2006 Sep;3(9):e358
PLoS medicine 2006 Sep;3(9):e358
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR4 Antibody (76B357.1) [PE] [NBP2-27149PE] - B16-F10 mouse melanoma cell line. Flow Cytometry image submitted by a verified customer review.