Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
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- Product number
- ABIN371647 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Toll-Like Receptor 4 (TLR4) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Purified
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1E11
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins.
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.
Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes.
Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B.
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex.
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.
Habich C, Baumgart K, Kolb H, Burkart V
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):569-76
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):569-76
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.
Asea A, Rehli M, Kabingu E, Boch JA, Bare O, Auron PE, Stevenson MA, Calderwood SK
The Journal of biological chemistry 2002 Apr 26;277(17):15028-34
The Journal of biological chemistry 2002 Apr 26;277(17):15028-34
Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes.
Dziarski R, Gupta D
Journal of endotoxin research 2000;6(5):401-5
Journal of endotoxin research 2000;6(5):401-5
Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B.
Jiang Q, Akashi S, Miyake K, Petty HR
Journal of immunology (Baltimore, Md. : 1950) 2000 Oct 1;165(7):3541-4
Journal of immunology (Baltimore, Md. : 1950) 2000 Oct 1;165(7):3541-4
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex.
Ohashi K, Burkart V, Flohé S, Kolb H
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 15;164(2):558-61
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 15;164(2):558-61
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.
Lien E, Means TK, Heine H, Yoshimura A, Kusumoto S, Fukase K, Fenton MJ, Oikawa M, Qureshi N, Monks B, Finberg RW, Ingalls RR, Golenbock DT
The Journal of clinical investigation 2000 Feb;105(4):497-504
The Journal of clinical investigation 2000 Feb;105(4):497-504
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S
Immunity 1999 Oct;11(4):443-51
Immunity 1999 Oct;11(4):443-51
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.
Zhang FX, Kirschning CJ, Mancinelli R, Xu XP, Jin Y, Faure E, Mantovani A, Rothe M, Muzio M, Arditi M
The Journal of biological chemistry 1999 Mar 19;274(12):7611-4
The Journal of biological chemistry 1999 Mar 19;274(12):7611-4
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M
The Journal of experimental medicine 1999 Jun 7;189(11):1777-82
The Journal of experimental medicine 1999 Jun 7;189(11):1777-82
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.
Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F
The Journal of biological chemistry 1999 Apr 16;274(16):10689-92
The Journal of biological chemistry 1999 Apr 16;274(16):10689-92
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