Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [3]
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- Product number
- ABIN252535 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Toll-Like Receptor 4 (TLR4) (AA 400-450), (Internal Region) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 400-450, Internal Region
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Progesterone elicits an inhibitory effect upon LPS-induced innate immune response in pre-labor human amniotic epithelium.
MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.
Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints.
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker.
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity.
Diverse microglial responses after intrahippocampal administration of lipopolysaccharide.
Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice.
Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6).
Innate immunity: the virtues of a nonclonal system of recognition.
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.
Flores-Espinosa P, Pineda-Torres M, Vega-Sánchez R, Estrada-Gutiérrez G, Espejel-Nuñez A, Flores-Pliego A, Maida-Claros R, Paredes-Vivas Y, Morales-Méndez I, Sosa-González I, Chávez-Mendoza A, Zaga-Clavellina V
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Jan;71(1):61-72
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Jan;71(1):61-72
MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.
Lu Z, Li Y, Samuvel DJ, Jin J, Zhang X, Lopes-Virella MF, Huang Y
Immunology 2013 Nov;140(3):301-13
Immunology 2013 Nov;140(3):301-13
Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints.
Li X, Kroin JS, Kc R, Gibson G, Chen D, Corbett GT, Pahan K, Fayyaz S, Kim JS, van Wijnen AJ, Suh J, Kim SG, Im HJ
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Dec;28(12):2512-22
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Dec;28(12):2512-22
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker.
Cammarota R, Bertolini V, Pennesi G, Bucci EO, Gottardi O, Garlanda C, Laghi L, Barberis MC, Sessa F, Noonan DM, Albini A
Journal of translational medicine 2010 Nov 8;8:112
Journal of translational medicine 2010 Nov 8;8:112
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
Barajon I, Serrao G, Arnaboldi F, Opizzi E, Ripamonti G, Balsari A, Rumio C
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity.
El Shikh ME, El Sayed RM, Wu Y, Szakal AK, Tew JG
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4444-50
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4444-50
Diverse microglial responses after intrahippocampal administration of lipopolysaccharide.
Herber DL, Maloney JL, Roth LM, Freeman MJ, Morgan D, Gordon MN
Glia 2006 Mar;53(4):382-91
Glia 2006 Mar;53(4):382-91
Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice.
Carrithers M, Tandon S, Canosa S, Michaud M, Graesser D, Madri JA
The American journal of pathology 2005 Jan;166(1):185-96
The American journal of pathology 2005 Jan;166(1):185-96
Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.
Chuang T, Ulevitch RJ
Biochimica et biophysica acta 2001 Mar 19;1518(1-2):157-61
Biochimica et biophysica acta 2001 Mar 19;1518(1-2):157-61
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S
Immunity 1999 Oct;11(4):443-51
Immunity 1999 Oct;11(4):443-51
The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6).
Muzio M, Natoli G, Saccani S, Levrero M, Mantovani A
The Journal of experimental medicine 1998 Jun 15;187(12):2097-101
The Journal of experimental medicine 1998 Jun 15;187(12):2097-101
Innate immunity: the virtues of a nonclonal system of recognition.
Medzhitov R, Janeway CA Jr
Cell 1997 Oct 31;91(3):295-8
Cell 1997 Oct 31;91(3):295-8
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr
Nature 1997 Jul 24;388(6640):394-7
Nature 1997 Jul 24;388(6640):394-7
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC