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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [20]
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- Product number
- NB100-56580 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56580, RRID:AB_839004
- Product name
- Rabbit Polyclonal TLR4 Antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody was developed against a sythetic peptide corresponding to amino acids 39-56 (CMDQKLSKVPDDIPSSTK) of mouse TLR4
- Reactivity
- Human, Mouse, Simian
- Host
- Rabbit
- Vial size
- 0.05mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Submitted references Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats.
Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.
Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface.
EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice.
Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome.
Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages.
Fipronil induces lung inflammation in vivo and cell death in vitro.
The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes.
CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.
Mycoplasma hyorhinis induces epithelial-mesenchymal transition in gastric cancer cell MGC803 via TLR4-NF-κB signaling.
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats.
Staphylococcal superantigen-like protein 3 binds to the Toll-like receptor 2 extracellular domain and inhibits cytokine production induced by Staphylococcus aureus, cell wall component, or lipopeptides in murine macrophages.
Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.
Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization.
Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.
Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury.
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Acute renal failure: determinants and characteristics of the injury-induced hyperinflammatory response.
Alanazi AM, Fadda L, Alhusaini A, Ahmad R, Hasan IH, Mahmoud AM
Antioxidants (Basel, Switzerland) 2020 Feb 16;9(2)
Antioxidants (Basel, Switzerland) 2020 Feb 16;9(2)
Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.
Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J, Mason JB, Crott JW
International journal of cancer 2018 Oct 1;143(7):1797-1805
International journal of cancer 2018 Oct 1;143(7):1797-1805
Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface.
Perconti G, Maranto C, Romancino DP, Rubino P, Feo S, Bongiovanni A, Giallongo A
Scientific reports 2017 Jun 19;7(1):3841
Scientific reports 2017 Jun 19;7(1):3841
EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice.
Oyama JI, Shiraki A, Nishikido T, Maeda T, Komoda H, Shimizu T, Makino N, Node K
Journal of cardiology 2017 Feb;69(2):417-427
Journal of cardiology 2017 Feb;69(2):417-427
Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome.
Compare D, Rocco A, Coccoli P, Angrisani D, Sgamato C, Iovine B, Salvatore U, Nardone G
BMC gastroenterology 2017 Apr 14;17(1):53
BMC gastroenterology 2017 Apr 14;17(1):53
Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages.
Deiuliis JA, Syed R, Duggineni D, Rutsky J, Rengasamy P, Zhang J, Huang K, Needleman B, Mikami D, Perry K, Hazey J, Rajagopalan S
PloS one 2016;11(11):e0165962
PloS one 2016;11(11):e0165962
Fipronil induces lung inflammation in vivo and cell death in vitro.
Merkowsky K, Sethi RS, Gill JP, Singh B
Journal of occupational medicine and toxicology (London, England) 2016;11:10
Journal of occupational medicine and toxicology (London, England) 2016;11:10
The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes.
Pahwa R, Devaraj S, Jialal I
International journal of obesity (2005) 2016 Jun;40(6):907-11
International journal of obesity (2005) 2016 Jun;40(6):907-11
CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.
Riehl TE, Santhanam S, Foster L, Ciorba M, Stenson WF
American journal of physiology. Gastrointestinal and liver physiology 2015 Dec 1;309(11):G874-87
American journal of physiology. Gastrointestinal and liver physiology 2015 Dec 1;309(11):G874-87
Mycoplasma hyorhinis induces epithelial-mesenchymal transition in gastric cancer cell MGC803 via TLR4-NF-κB signaling.
Duan H, Qu L, Shou C
Cancer letters 2014 Nov 28;354(2):447-54
Cancer letters 2014 Nov 28;354(2):447-54
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Balamurugan K, Sharan S, Klarmann KD, Zhang Y, Coppola V, Summers GH, Roger T, Morrison DK, Keller JR, Sterneck E
Nature communications 2013;4:1662
Nature communications 2013;4:1662
Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats.
Oyama J, Maeda T, Sasaki M, Higuchi Y, Node K, Makino N
American journal of physiology. Heart and circulatory physiology 2012 May 15;302(10):H2092-101
American journal of physiology. Heart and circulatory physiology 2012 May 15;302(10):H2092-101
Staphylococcal superantigen-like protein 3 binds to the Toll-like receptor 2 extracellular domain and inhibits cytokine production induced by Staphylococcus aureus, cell wall component, or lipopeptides in murine macrophages.
Yokoyama R, Itoh S, Kamoshida G, Takii T, Fujii S, Tsuji T, Onozaki K
Infection and immunity 2012 Aug;80(8):2816-25
Infection and immunity 2012 Aug;80(8):2816-25
Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M
International immunology 2010 Apr;22(4):271-80
International immunology 2010 Apr;22(4):271-80
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.
Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT
Infection and immunity 2008 Oct;76(10):4385-95
Infection and immunity 2008 Oct;76(10):4385-95
Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization.
Shimada M, Yanai Y, Okazaki T, Noma N, Kawashima I, Mori T, Richards JS
Development (Cambridge, England) 2008 Jun;135(11):2001-11
Development (Cambridge, England) 2008 Jun;135(11):2001-11
Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.
Bondeva T, Roger T, Wolf G
American journal of nephrology 2007;27(3):308-14
American journal of nephrology 2007;27(3):308-14
Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury.
Zager RA, Johnson AC, Lund S, Randolph-Habecker J
American journal of physiology. Renal physiology 2007 Jan;292(1):F304-12
American journal of physiology. Renal physiology 2007 Jan;292(1):F304-12
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1855-63
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1855-63
Acute renal failure: determinants and characteristics of the injury-induced hyperinflammatory response.
Zager RA, Johnson AC, Lund S, Hanson S
American journal of physiology. Renal physiology 2006 Sep;291(3):F546-56
American journal of physiology. Renal physiology 2006 Sep;291(3):F546-56
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