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- Product number
- ABIN783332 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 1057-1061) antibody
- Antibody type
- Polyclonal
- Description
- Affinity-chromatography using epitope-specific peptide
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Antigen sequence
P-D-Y-V-R- Epitope
- AA 1057-1061
- Vial size
- 0.1 mL
- Storage
- Store (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively.
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization.
Zeng H, Sanyal S, Mukhopadhyay D
The Journal of biological chemistry 2001 Aug 31;276(35):32714-9
The Journal of biological chemistry 2001 Aug 31;276(35):32714-9
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization.
Dougher M, Terman BI
Oncogene 1999 Feb 25;18(8):1619-27
Oncogene 1999 Feb 25;18(8):1619-27
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