KDR

gene product
CD309, FLK1, VEGFR, VEGFR2
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
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AntibodyRefsTypeAVIWBELICCIPIHCFC
R&D Systems
38 antibodies
ReliaTech GmbH
17 antibodies
Novus Biologicals
228 antibodies
Abgent
13 antibodies
antibodies-online
601 antibodies