Antibody data
- Antibody Data
- Antigen structure
- References [171]
- Comments [0]
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- Product number
- 26415-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#26415-1-AP, RRID:AB_2756527
- Product name
- VEGFR2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VEGFR2 antibody (Cat. #26415-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling.
Babaodan suppresses inflammatory and vascular microenvironment in triple-negative breast cancer by inhibiting the cGAS-STING/NF-κB signaling pathway.
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice.
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
A novel molecule ZYZ329 targeting histone methyltransferase SMYD3 suppresses pathological angiogenesis via the driven mitochondrial ROS/HIF-1α/VEGFA axis.
Salvianolic acid A, salvianolic acid B, and Danshensu promote angiogenesis by enhancing glycolysis of endothelial cells during myocardial infarction treatment.
PSMA-Targeting Macrophage Membrane-Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer.
Structure-Based Discovery of Novel, Highly Potent VEGFR2 Inhibitors with a Naphthalene Scaffold against a Broad Range of Solid Tumors.
Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity.
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells.
Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway.
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.
Spatial Single-Cell Atlas Reveals KSHV-Driven Broad Cellular Reprogramming, Progenitor Expansion, Immune and Vascular Remodeling in Kaposi's Sarcoma.
Jiao-Ai Decoction and active ingredients promoted angiogenesis to alleviate threatened abortion through miR-16 mediated VEGF/VEGFR signaling pathway.
Decabromodiphenyl ethane induces intrauterine growth restriction by suppressing placental angiogenesis via TWIST2/NAT10-mediated ac4C-dependent TGF-β1 mRNA stabilization.
SNX17 knockdown improves post-ischemic angiogenesis via blocking lysosomal dependent VEGFR degradation.
Bruceine D inhibits CAF-promoted angiogenesis of breast cancer via suppressing IL-6-mediated activation of the STAT3/Notch1/VEGFR2 axis.
Maternal fish oil supplementation enhances nutrient transport in the placenta and milk biosynthesis in the mammary gland via the GPR120 signaling pathway.
Exploring the Efficacy of AZD6738 in Corneal Neovascularization: Autophagy Enhancement and Angiogenesis Inhibition.
Caulerpin suppresses tumor-associated angiogenesis and tumor growth via Hippo signaling in cervical cancer.
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
iRGD-modified co-loaded curcumin piperine liposomes inhibit angiogenesis in non-small cell lung cancer through the VEGFR2/P38/MK2 signaling axis.
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
ELF3-regulated PES1 targets VEGFR2 to mediate angiogenesis and retinal inner barrier injury in diabetic retinopathy.
Proline betaine facilitates angiogenesis in bronchopulmonary dysplasia.
Kaempferol promotes angiogenesis through HIF-1α/VEGF-A/Notch1 pathway in ischemic stroke rats.
Transplantation of autologous endothelial progenitor cells promotes the repair of fusiform aneurysms.
Electroacupuncture ameliorates cognitive impairment and white matter injury in vascular dementia rats via activating HIF-1α/VEGF/VEGFR2 pathway.
Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma.
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
LncRNA SNHG15 promotes angiogenesis and improves cardiac repair after myocardial infarction through MiR-665-mediated KDR expression.
BACH1 deficiency improves placental angiogenesis via SLC25A51-mediated mitochondrial NAD(+) transport in intrahepatic cholestasis of pregnancy.
Tianlong Kechuanling decoction attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition.
Increased ocular plasma cells induce damaging α-synuclein(+) microglia in autoimmune uveitis.
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Salvianolic Acid B Promotes Placental and Decidual Angiogenesis by Restoring the Normal Expression of Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor in Mice With Recurrent Pregnancy Loss.
Bioactive vascular buds promote collateral vessel formation by grafting on the artificial vessel walls.
Curcumin alleviates ovarian hyperstimulation syndrome in the rat model via inhibiting the nuclear factor kappa B/hypoxia-inducible factor-1α signaling pathway.
Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence.
S100A16 stabilizes the ITGA3‑mediated ECM‑receptor interaction pathway to drive the malignant properties of lung adenocarcinoma cells via binding MOV10.
Macrophage Membrane-Biomimetic Multi-Layered Nanoparticles Targeting Synovial Angiogenesis for Osteoarthritis Therapy.
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Mechanical energy-charged navigating pump repair natural vascular scaffolds to reverse osteoporosis.
Structural characterisation of a polysaccharide from Sanghuangporus vaninii and its synergistic anti-hepatocellular carcinoma activity in combination with sorafenib.
DHHC5 regulates lacteal function and intestinal lipid absorption by maintaining VEGFR2 localization in lipid rafts.
Endothelial Piezo1 stimulates angiogenesis to offer protection against intestinal ischemia-reperfusion injury in mice.
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA.
Promotion of tumor angiogenesis and growth induced by low-dose antineoplastic agents via bone-marrow-derived cells in tumor tissues.
The natural compound sinometumine E derived from Corydalis decumbens promotes angiogenesis by regulating HIF-1/ VEGF pathway in vivo and in vitro.
Enhanced Mechanical Strength and Sustained Drug Release in Carrier-Free Silver-Coordinated Anthraquinone Natural Antibacterial Anti-Inflammatory Hydrogel for Infectious Wound Healing.
Nuclear receptor 4A1 ameliorates renal fibrosis by inhibiting vascular endothelial growth factor A induced angiogenesis in UUO rats.
Hirudin delays the progression of diabetic kidney disease by inhibiting glomerular endothelial cell migration and abnormal angiogenesis.
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury.
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Jianwei Xiaoyan granule ameliorates chronic atrophic gastritis by regulating HIF-1α-VEGF pathway.
Modulation of SRC by SNTB1 activates the Hippo-YAP pathway during colon adenocarcinoma metastasis.
Vasorin promotes endothelial differentiation of glioma stem cells via stimulating the transcription of VEGFR2.
VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis.
Rutaecarpine protects podocytes in diabetic kidney disease by targeting VEGFR2/NLRP3-mediated pyroptosis.
Synergistic promotion of angiogenesis after intracerebral hemorrhage by ginsenoside Rh2 and chrysophanol in rats.
Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids.
Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma.
AUY922 improves sensitivity to sunitinib in clear cell renal cell carcinoma based on network pharmacology and in vitro experiments.
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway.
Comprehensive analysis of PHF5A as a potential prognostic biomarker and therapeutic target across cancers and in hepatocellular carcinoma.
CHRDL2 activates the PI3K/AKT pathway to ameliorate glucocorticoid-induced damages to bone microvascular endothelial cells (BMECs).
Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditions.
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Inhibition of soluble epoxide hydrolase enhances the dentin-pulp complex regeneration mediated by crosstalk between vascular endothelial cells and dental pulp stem cells.
Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
Nicotinamide Riboside Modulates HIF-1 Signaling to Maintain and Enhance Odontoblastic Differentiation in Human Dental Pulp Stem Cells.
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Restoring sweat gland function in mice using regenerative sweat gland cells derived from chemically reprogrammed human epidermal keratinocytes.
Isosilybin A exhibits anti-inflammatory properties in rosacea by inhibiting MAPK pathway and M1 macrophage polarization.
PAI-1 promotes human endometrial stromal decidualization via inhibiting VEGFR2/PI3K/AKT signaling pathway mediated F-actin reorganization.
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
rTMS Ameliorates time-varying depression and social behaviors in stimulated space complex environment associated with VEGF signaling.
Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke.
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
A Nucleic Acid-Based LYTAC Plus Platform to Simultaneously Mediate Disease-Driven Protein Downregulation.
Elevated MPP6 expression correlates with an unfavorable prognosis, angiogenesis and immune evasion in hepatocellular carcinoma.
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
LncRNA PVT1 promotes strong stemness and endothelial progenitor cell characteristics in renal carcinoma stem cells.
Effect of Extracellular Ribonucleic Acids on Neurovascularization in Osteoarthritis.
Gap26 inhibited angiogenesis through the β-catenin-VE-cadherin-VEGFR2-Erk signaling pathway.
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway.
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
BEST1 Positive Monocytes in Circulation: Visualize Intratumoral Crosstalk between Cancer Cells and Monocytes.
Low Pi stress enhances the sensitivity of hepatocellular carcinoma to sorafenib.
Andrographolide improves the dysfunction of endothelial progenitor cells from angiotensin II-induced hypertensive mice through SIRT1 signaling.
SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis.
Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis.
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Saponin of Aralia taibaiensis promotes angiogenesis through VEGF/VEGFR2 signaling pathway in cerebral ischemic mice.
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
YAP/STAT3 inhibited CD8(+) T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
A novel implant surface modification mode of Fe3O4-containing TiO2 nanorods with sinusoidal electromagnetic field for osteoblastogenesis and angiogenesis.
Upregulation of Cell Surface Glycoproteins in Correlation with KSHV LANA in the Kaposi Sarcoma Tumor Microenvironment.
Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway.
VEGF receptor heterodimers and homodimers are differentially expressed in neuronal and endothelial cell types.
Antidepressant-Like Effect and Mechanism of Ginsenoside Rd on Rodent Models of Depression.
Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.
Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation.
Mesenchymal Stem Cells-Derived Exosomes Ameliorate Ischemia/Reperfusion Induced Acute Kidney Injury in a Porcine Model.
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
Construction and a preliminary study of paracrine effect of bone marrow-derived endothelial progenitor cell sheet.
The crescendo pulse frequency of shear stress stimulates the endothelialization of bone marrow mesenchymal stem cells on the luminal surface of decellularized scaffold in the bioreactor.
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma.
Cellular heterogeneity and immune microenvironment revealed by single-cell transcriptome in venous malformation and cavernous venous malformation.
Impact of repeated intravenous infusions of umbilical cord-derived versus bone marrow-derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model.
PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis.
Kaposi's sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene.
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold.
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease.
Berberine prevents diabetic retinopathy through inhibiting HIF-1α /VEGF/ NF-κ B pathway in db/db mice.
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy.
BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Zoledronate Inhibits Osteoclast Differentiation via Suppressing Vascular Endothelial Growth Factor Receptor 2 Expression.
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Protective Effects of Combination of Radix Astragali and Radix Salviae Miltiorrhizae on Kidney of Spontaneously Hypertensive Rats and Renal Intrinsic Cells.
Aerobic and resistance training enhances endothelial progenitor cell function via upregulation of caveolin-1 in mice with type 2 diabetes.
Brivanib, a multitargeted small-molecule tyrosine kinase inhibitor, suppresses laser-induced CNV in a mouse model of neovascular AMD.
Anti-angiogenic activity of ShengMaBieJia decoction in vitro and in acute myeloid leukaemia tumour-bearing mouse models.
MiR-17-5p promotes the endothelialization of endothelial progenitor cells to facilitate the vascular repair of aneurysm by regulating PTEN-mediated PI3K/AKT/VEGFA pathway.
Qingjie Fuzheng Granules regulates cancer cell proliferation, apoptosis and tumor angiogenesis in colorectal cancer xenograft mice via Sonic Hedgehog pathway.
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Effect of Aerobic and Resistance Training on Endothelial Progenitor Cells in Mice with Type 2 Diabetes.
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
PlGF signaling and macrophage repolarization contribute to the anti-neoplastic effect of metformin.
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Exosomes derived from acute myeloid leukemia cells promote chemoresistance by enhancing glycolysis-mediated vascular remodeling.
VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.
Myricetin Inhibits Breast Tumor Growth and Angiogenesis by Regulating VEGF/VEGFR2 and p38MAPK Signaling Pathways.
Human Colorectal Cancer Infrastructure Constructed by the Glycocalyx.
Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R.
Resveratrol Promotes Nerve Regeneration via Activation of p300 Acetyltransferase-Mediated VEGF Signaling in a Rat Model of Sciatic Nerve Crush Injury.
SK-Hep1: not hepatocellular carcinoma cells but a cell model for liver sinusoidal endothelial cells.
Effects of l-arginine on endometrial microvessel density in nutrient-restricted Hu sheep.
miR‑1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor.
Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation.
Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.
Eupolyphaga sinensis Walker demonstrates angiogenic activity and inhibits A549 cell growth by targeting the KDR signaling pathway.
Chai P, Kheiri S, Kuo A, Shah J, Kageler L, Ge R, Perr J, Porat J, Lebedenko CG, Dias JML, Yankova E, Rai SK, Watkins CP, Hristov P, Tzelepis K, Hla T, Raman R, Calo E, Esko JD, Flynn RA
Nature 2026 Mar;651(8106):808-818
Nature 2026 Mar;651(8106):808-818
Babaodan suppresses inflammatory and vascular microenvironment in triple-negative breast cancer by inhibiting the cGAS-STING/NF-κB signaling pathway.
Lai B, Zeng W, Zhou B, Liu R, Lai P, Ren J, Chen R, Che L, Chen X, Pei X, Qiu Y
Journal of ethnopharmacology 2026 Jun 12;364:121515
Journal of ethnopharmacology 2026 Jun 12;364:121515
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
Li Z, Xiao Y, Zhou S, Lam M, Ding Y, Lin R, Yang M, Liang S, Tao J
Brain research bulletin 2026 Jun 1;239:111858
Brain research bulletin 2026 Jun 1;239:111858
MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice.
Chen D, Zhao HM, Sun XL, Xing ZX, Li SP, Li SC, Wu YX, Pang QF, Huang JF
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Tao Y, Du M, Zhu M, Sun W, Zeng G, Xiong J, Li J, Yang Z, Fan B, Zhang R, Zeng G
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Shen T, Lin R, Zheng T, Yu J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
A novel molecule ZYZ329 targeting histone methyltransferase SMYD3 suppresses pathological angiogenesis via the driven mitochondrial ROS/HIF-1α/VEGFA axis.
Ye Q, Cai J, Lu X, Zhu Q, Li Q, Ren M, Ding Q, Mao Y, Zhu YZ
Journal of translational medicine 2026 Feb 24;24(1)
Journal of translational medicine 2026 Feb 24;24(1)
Salvianolic acid A, salvianolic acid B, and Danshensu promote angiogenesis by enhancing glycolysis of endothelial cells during myocardial infarction treatment.
Li W, Tao X, Liu K, Dai Q, Liu C, Yao H, Wang H, Ding Z, Chen S, Wang W, Wei P, Xi M, Zhang S
Journal of ethnopharmacology 2026 Aug 10;367:121679
Journal of ethnopharmacology 2026 Aug 10;367:121679
PSMA-Targeting Macrophage Membrane-Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer.
Zhang K, Gao B, Wang J, Li Y, Xu C, Yang F, Liu S, Li H, Zhang C, Meng X, Shi Z, Zhang R, Zhang R, Wang Z, Wen W, Zhang Q, Zou Y, Han D, Bian H, Qin W
Exploration (Beijing, China) 2026 Apr;6(2):20240393
Exploration (Beijing, China) 2026 Apr;6(2):20240393
Structure-Based Discovery of Novel, Highly Potent VEGFR2 Inhibitors with a Naphthalene Scaffold against a Broad Range of Solid Tumors.
Yang T, Wei T, Sun S, Xi B, Wei P, Jia C, Qi Z, Feng F, Wei M, Wang Y, Cai X, Zhao Z, Li B, Qiao M, Zou Y, Mu Z, Lei X, Zhang Z, Lei G, Lv K, Zheng Z, Li P, Li S
Journal of medicinal chemistry 2026 Apr 9;69(7):8340-8363
Journal of medicinal chemistry 2026 Apr 9;69(7):8340-8363
Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity.
Meng H, Chang Q, Zhang Y, Ren J, Guo H, Yu L, Qian C, Jiang Y, Zhang L, Cheng W
Science advances 2026 Apr 17;12(16):eaeb0855
Science advances 2026 Apr 17;12(16):eaeb0855
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Li M, Song J, Niu X, Mo F, Xie X, Li X, Yin Y, Wang T, Song X, Liu J, Lv P
Frontiers in aging neuroscience 2025;17:1521353
Frontiers in aging neuroscience 2025;17:1521353
Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells.
Xie Y, Zhang J, Du R, Ji J, Lu J, Li H, Xu Y, Zhang Y, Cheng X
Frontiers in cell and developmental biology 2025;13:1650614
Frontiers in cell and developmental biology 2025;13:1650614
Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway.
Maksimoska V, Dan Q, Rambharack N, Szászi K
Frontiers in cell and developmental biology 2025;13:1601887
Frontiers in cell and developmental biology 2025;13:1601887
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Wan YH, Cheng ZJ, Fan LX, Yang DH, Chen BL, Chen XX, Zhu Q
Molecular neurobiology 2025 Sep;62(9):11112-11129
Molecular neurobiology 2025 Sep;62(9):11112-11129
Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.
Yao Z, He J, Hu M, Yan P, Xu Q, Zhang Q, Lin Y, Liao J, Cai X, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157086
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157086
Spatial Single-Cell Atlas Reveals KSHV-Driven Broad Cellular Reprogramming, Progenitor Expansion, Immune and Vascular Remodeling in Kaposi's Sarcoma.
Meng W, Das A, Sinha H, Naous R, Bracci PM, McGrath M, Huang Y, Gao SJ
bioRxiv : the preprint server for biology 2025 Sep 5;
bioRxiv : the preprint server for biology 2025 Sep 5;
Jiao-Ai Decoction and active ingredients promoted angiogenesis to alleviate threatened abortion through miR-16 mediated VEGF/VEGFR signaling pathway.
Deng J, Jing S, Zhang M, Quan X, Hu X, Yun J, Geng T, Zhang Y, Zhang L
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120385
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120385
Decabromodiphenyl ethane induces intrauterine growth restriction by suppressing placental angiogenesis via TWIST2/NAT10-mediated ac4C-dependent TGF-β1 mRNA stabilization.
Ling R, Yin X, Ma L, Zhang Y, Ma Y, Gao R, Geng Y, Mu X, Chen X, Li F, He J
Journal of hazardous materials 2025 Sep 15;496:139377
Journal of hazardous materials 2025 Sep 15;496:139377
SNX17 knockdown improves post-ischemic angiogenesis via blocking lysosomal dependent VEGFR degradation.
Tang Y, Tang S, Chen Y, Zhang J, Yu X, Mao P, Wang W, Yu J, Wang F, Zeng C
Life sciences 2025 Sep 15;377:123739
Life sciences 2025 Sep 15;377:123739
Bruceine D inhibits CAF-promoted angiogenesis of breast cancer via suppressing IL-6-mediated activation of the STAT3/Notch1/VEGFR2 axis.
Ma J, Cao D, Zhang Y, Sun Y, Wu Y, Wang J
European journal of pharmacology 2025 Sep 15;1003:177994
European journal of pharmacology 2025 Sep 15;1003:177994
Maternal fish oil supplementation enhances nutrient transport in the placenta and milk biosynthesis in the mammary gland via the GPR120 signaling pathway.
Li Q, Zhang Q, Su S, Yang S, Shao J, Guan W, Zhang S
Journal of advanced research 2025 Oct;76:73-89
Journal of advanced research 2025 Oct;76:73-89
Exploring the Efficacy of AZD6738 in Corneal Neovascularization: Autophagy Enhancement and Angiogenesis Inhibition.
Wang Q, Peng Y, Wang S, Xu J, Cheng C, Luo X, Yu K, Yao W, Pi Y, Zhu Z, Yu Y
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Oct;41(8):444-454
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Oct;41(8):444-454
Caulerpin suppresses tumor-associated angiogenesis and tumor growth via Hippo signaling in cervical cancer.
Yang G, Mo Y, Rong H, Guo B, Zha Q, Shuai H, Wang M, Li P
Toxicology and applied pharmacology 2025 Nov;504:117541
Toxicology and applied pharmacology 2025 Nov;504:117541
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
Fan W, You Y, Qu Y, Liu G
Molecular immunology 2025 Nov;187:152-165
Molecular immunology 2025 Nov;187:152-165
iRGD-modified co-loaded curcumin piperine liposomes inhibit angiogenesis in non-small cell lung cancer through the VEGFR2/P38/MK2 signaling axis.
Huang X, Chen Y, Chen J, Lin J, Zhuang Y, Huang M, Yu H, Wang M, Wang Y, Wang Y
Discover oncology 2025 Nov 7;16(1):2056
Discover oncology 2025 Nov 7;16(1):2056
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
Li J, He M, Huang M, Xiang J, Zhang L, Liu Y, Ma Y, Zeng X, Sun X
Scientific reports 2025 Nov 4;15(1):38574
Scientific reports 2025 Nov 4;15(1):38574
ELF3-regulated PES1 targets VEGFR2 to mediate angiogenesis and retinal inner barrier injury in diabetic retinopathy.
Liu S, Hou J, Tao Y, Xu Y, Liu J, Lin S, Tao L, Jiang Z
Journal of translational medicine 2025 Nov 18;23(1):1309
Journal of translational medicine 2025 Nov 18;23(1):1309
Proline betaine facilitates angiogenesis in bronchopulmonary dysplasia.
Cili W, Qi Z, Zhong Q, Li Y, Huang X, Yang R, Tang S, Li Q, Yang L, Ning Y, Xie Y, Feng Y, Duan J
Toxicology and applied pharmacology 2025 May;498:117301
Toxicology and applied pharmacology 2025 May;498:117301
Kaempferol promotes angiogenesis through HIF-1α/VEGF-A/Notch1 pathway in ischemic stroke rats.
Zhang S, Liu C, Li W, Zhang Y, Yang Y, Yang H, Zhao Z, Xu F, Cao W, Li X, Wang J, Kong L, Du G
Neurochemistry international 2025 May;185:105953
Neurochemistry international 2025 May;185:105953
Transplantation of autologous endothelial progenitor cells promotes the repair of fusiform aneurysms.
Zhang L, Ni S, Zhang W, Shi J, Ding J, Xu X, Zhang S, Zhang Y, Jiang T
Microvascular research 2025 May;159:104794
Microvascular research 2025 May;159:104794
Electroacupuncture ameliorates cognitive impairment and white matter injury in vascular dementia rats via activating HIF-1α/VEGF/VEGFR2 pathway.
Yang Y, Rao T, Jiang Y, Zhan Y, Cheng J, Yin Z, Ma K, Zhong X, Guo X, Yang S
Neuroscience 2025 May 7;573:364-380
Neuroscience 2025 May 7;573:364-380
Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma.
Sun H, Wang G, Ren C, Zhang X, Zhao P, Guo B
Scientific reports 2025 May 6;15(1):15766
Scientific reports 2025 May 6;15(1):15766
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
Zhang SP, Tong M, Mo J, Dong ZY, Huang YF
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
LncRNA SNHG15 promotes angiogenesis and improves cardiac repair after myocardial infarction through MiR-665-mediated KDR expression.
Liang X, Liu S, Liu G, Fan Q, Ma F, Yin Y, Li Z, Wu Y, Zheng M
Cellular and molecular life sciences : CMLS 2025 May 26;82(1):211
Cellular and molecular life sciences : CMLS 2025 May 26;82(1):211
BACH1 deficiency improves placental angiogenesis via SLC25A51-mediated mitochondrial NAD(+) transport in intrahepatic cholestasis of pregnancy.
Li S, Zhu W, Xing Z, Chen D, Zhao H, Zhang Y, Zhang W, Sun J, Wu Y, Ai L, Pang Q
Molecular medicine (Cambridge, Mass.) 2025 May 1;31(1):162
Molecular medicine (Cambridge, Mass.) 2025 May 1;31(1):162
Tianlong Kechuanling decoction attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition.
Gong J, Li H, Cui X, Yan Y, Yu Q, Ding Q, Shi Y, Wang P
Journal of ethnopharmacology 2025 Mar 13;343:119395
Journal of ethnopharmacology 2025 Mar 13;343:119395
Increased ocular plasma cells induce damaging α-synuclein(+) microglia in autoimmune uveitis.
Li M, Feng M, Liu T, Duan S, Man X, Yuan X, Wang L, Sun Y, Wei X, Fu Q, Sun B, Lin W
Mucosal immunology 2025 Jun;18(3):668-684
Mucosal immunology 2025 Jun;18(3):668-684
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Cao L, Shangguan Z, Zhang Y, Luo Z, Chen C, Yan H, Fu X, Tan W, Wang C, Dou X, Zheng C, Li Q
Cellular signalling 2025 Jun;130:111675
Cellular signalling 2025 Jun;130:111675
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471
ACS nano 2025 Jun 10;19(22):20452-20471
Salvianolic Acid B Promotes Placental and Decidual Angiogenesis by Restoring the Normal Expression of Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor in Mice With Recurrent Pregnancy Loss.
Hu F, Yang C, Dai L, Gao D, Luo H, Zhong X, Chen P, Zhu L, Xiao Z, Zhao S, Huang G
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jul;94(1):e70105
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jul;94(1):e70105
Bioactive vascular buds promote collateral vessel formation by grafting on the artificial vessel walls.
Yang Y, Qiu Y, Xu S, Gao H, Wang C, Huang H, Yang Z, Chen X, Zhao F
Bioactive materials 2025 Jul;49:564-575
Bioactive materials 2025 Jul;49:564-575
Curcumin alleviates ovarian hyperstimulation syndrome in the rat model via inhibiting the nuclear factor kappa B/hypoxia-inducible factor-1α signaling pathway.
Sun L, Zhuo X, Qi D, Ma H, Kong F, Sun P, Zhang Y, Xue P, Ma H
Histochemistry and cell biology 2025 Jul 12;163(1):75
Histochemistry and cell biology 2025 Jul 12;163(1):75
Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence.
Liang F, Huang N, Tian Y, Fang Y, Huang C, Qiu B, Lu T, Zheng L, Cheng J, Zhu B, Zhao J
Stem cell research & therapy 2025 Jul 1;16(1):341
Stem cell research & therapy 2025 Jul 1;16(1):341
S100A16 stabilizes the ITGA3‑mediated ECM‑receptor interaction pathway to drive the malignant properties of lung adenocarcinoma cells via binding MOV10.
Yang L, Shen A, Wang R, Zheng Z
Molecular medicine reports 2025 Jan;31(1)
Molecular medicine reports 2025 Jan;31(1)
Macrophage Membrane-Biomimetic Multi-Layered Nanoparticles Targeting Synovial Angiogenesis for Osteoarthritis Therapy.
Liao J, Zhu Z, Zou J, Liu S, Luo X, Bao W, Du C, Lei Y, Huang W
Advanced healthcare materials 2025 Jan;14(2):e2401985
Advanced healthcare materials 2025 Jan;14(2):e2401985
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Mao X, Wang C, Tang H, Liu X, Wei C, Yin F, Fu T, Fang Y, Yu K, Zhang Z, Wu C, Liu H, Le A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Wu X, Zhuo Y, Liu J, He Z, Wang M, Lei W, Liang Q, Wang A, Shen Z, Chen S, Zheng S, Huang H
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Mechanical energy-charged navigating pump repair natural vascular scaffolds to reverse osteoporosis.
Wang F, Yang S, Zhu Y, Zhang Y, He W, Zhang S, Xiao J, Fu C, Wang P, Chen J, Wang J, Zhao H, Chen W, Zhang Y
Materials today. Bio 2025 Dec;35:102431
Materials today. Bio 2025 Dec;35:102431
Structural characterisation of a polysaccharide from Sanghuangporus vaninii and its synergistic anti-hepatocellular carcinoma activity in combination with sorafenib.
Li J, Shi M, Jia B, Liu S, Zhao Y
International journal of biological macromolecules 2025 Dec;334(Pt 1):148778
International journal of biological macromolecules 2025 Dec;334(Pt 1):148778
DHHC5 regulates lacteal function and intestinal lipid absorption by maintaining VEGFR2 localization in lipid rafts.
Zhao YY, Li YF, Hao JW, Zhao N, Men XT, Bai XY, Tai R, Ye HB, Du XR, Guo HL, Wang J, Qian HJ, Zhao TJ
Life metabolism 2025 Aug;4(4):loaf014
Life metabolism 2025 Aug;4(4):loaf014
Endothelial Piezo1 stimulates angiogenesis to offer protection against intestinal ischemia-reperfusion injury in mice.
Wang C, Luo S, Yan Y, Li J, Niu W, Hong T, Hao K, Sun X, Liu J, An R, Li J
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):147
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):147
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
He J, Yin L, Yuan Q, Su X, Shen Y, Deng Z
World journal of surgical oncology 2025 Apr 2;23(1):115
World journal of surgical oncology 2025 Apr 2;23(1):115
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA.
Liu Y, Wang Z, Tang Z, Fu Y, Wang L
Current cancer drug targets 2024;24(4):463-475
Current cancer drug targets 2024;24(4):463-475
Promotion of tumor angiogenesis and growth induced by low-dose antineoplastic agents via bone-marrow-derived cells in tumor tissues.
You H, Zhao P, Zhao X, Zheng Q, Ma W, Cheng K, Li M, Kou J, Feng W
Frontiers in pharmacology 2024;15:1414832
Frontiers in pharmacology 2024;15:1414832
The natural compound sinometumine E derived from Corydalis decumbens promotes angiogenesis by regulating HIF-1/ VEGF pathway in vivo and in vitro.
Wang Y, Wang S, Wang Y, Gao P, Wang L, Wang Q, Zhang Y, Liu K, Xia Q, Tu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117113
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117113
Enhanced Mechanical Strength and Sustained Drug Release in Carrier-Free Silver-Coordinated Anthraquinone Natural Antibacterial Anti-Inflammatory Hydrogel for Infectious Wound Healing.
Liang X, Ding L, Ma J, Li J, Cao L, Liu H, Teng M, Li Z, Peng Y, Chen H, Zheng Y, Cheng H, Liu G
Advanced healthcare materials 2024 Sep;13(23):e2400841
Advanced healthcare materials 2024 Sep;13(23):e2400841
Nuclear receptor 4A1 ameliorates renal fibrosis by inhibiting vascular endothelial growth factor A induced angiogenesis in UUO rats.
Wang H, Fang F, Zhang M, Xu C, Liu J, Gao L, Zhao C, Wang Z, Zhong Y, Wang X
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119813
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119813
Hirudin delays the progression of diabetic kidney disease by inhibiting glomerular endothelial cell migration and abnormal angiogenesis.
Zhang J, Li Y, Zhang F, Zhang Y, Zhang L, Zhao Y, Liu X, Su J, Yu X, Wang W, Zhao L, Tong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117300
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117300
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Xiong W, Zheng B, Liu D, Pu M, Zhou S, Deng Y
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury.
Xiao H, Liu S, Fang B, Zhang W, Wang M, Ye J, Huang T, Cao L, Zhang X, Sun G
Journal of ginseng research 2024 Nov;48(6):592-602
Journal of ginseng research 2024 Nov;48(6):592-602
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Su W, Ling Y, Yang X, Wu Y, Xing C
Journal of translational medicine 2024 Nov 18;22(1):1037
Journal of translational medicine 2024 Nov 18;22(1):1037
Jianwei Xiaoyan granule ameliorates chronic atrophic gastritis by regulating HIF-1α-VEGF pathway.
Liu J, Li M, Chen G, Yang J, Jiang Y, Li F, Hua H
Journal of ethnopharmacology 2024 Nov 15;334:118591
Journal of ethnopharmacology 2024 Nov 15;334:118591
Modulation of SRC by SNTB1 activates the Hippo-YAP pathway during colon adenocarcinoma metastasis.
Chang Z, Huang R, Song J, Li Z, Pi M, Xian S, Zhang J, Huang J, Xie R, Ji G, Han D, Huang Q
Journal of translational medicine 2024 Nov 15;22(1):1029
Journal of translational medicine 2024 Nov 15;22(1):1029
Vasorin promotes endothelial differentiation of glioma stem cells via stimulating the transcription of VEGFR2.
Qin Z, Zhong Y, Li P, Ma Z, Kang H, Huang Y, Zhong Y, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23682
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23682
VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis.
Guo M, Zhang J, Han J, Hu Y, Ni H, Yuan J, Sun Y, Liu M, Gao L, Liao W, Ma C, Liu Y, Li S, Li N
Journal of translational medicine 2024 May 3;22(1):419
Journal of translational medicine 2024 May 3;22(1):419
Rutaecarpine protects podocytes in diabetic kidney disease by targeting VEGFR2/NLRP3-mediated pyroptosis.
Hu X, Wang J, Jiang L, Liu X, Ge Q, Wang Q, Qi X, Wu Y
International immunopharmacology 2024 Mar 30;130:111790
International immunopharmacology 2024 Mar 30;130:111790
Synergistic promotion of angiogenesis after intracerebral hemorrhage by ginsenoside Rh2 and chrysophanol in rats.
Li M, Zhou H, Pan Z, Shi M, Yang J, Guo J, Wan H
Bioorganic chemistry 2024 Jun;147:107416
Bioorganic chemistry 2024 Jun;147:107416
Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids.
Dao L, You Z, Lu L, Xu T, Sarkar AK, Zhu H, Liu M, Calandrelli R, Yoshida G, Lin P, Miao Y, Mierke S, Kalva S, Zhu H, Gu M, Vadivelu S, Zhong S, Huang LF, Guo Z
Cell stem cell 2024 Jun 6;31(6):818-833.e11
Cell stem cell 2024 Jun 6;31(6):818-833.e11
Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma.
Bai Y, You Y, Chen D, Chen Y, Yin Z, Liao S, You B, Lu D, Sun Y, Wu L, Wu Y
iScience 2024 Jun 21;27(6):109997
iScience 2024 Jun 21;27(6):109997
AUY922 improves sensitivity to sunitinib in clear cell renal cell carcinoma based on network pharmacology and in vitro experiments.
Chen Z, Jia X, Cai Y, Song Y, Tong Y, Cheng S, Liu M
Heliyon 2024 Jul 30;10(14):e34834
Heliyon 2024 Jul 30;10(14):e34834
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway.
Zhong Y, Kang H, Ma Z, Li J, Qin Z, Zhang Z, Li P, Zhong Y, Wang L
Molecular cancer research : MCR 2024 Jul 2;22(7):668-681
Molecular cancer research : MCR 2024 Jul 2;22(7):668-681
Comprehensive analysis of PHF5A as a potential prognostic biomarker and therapeutic target across cancers and in hepatocellular carcinoma.
Cheng Q, Ji W, Lv Z, Wang W, Xu Z, Chen S, Zhang W, Shao Y, Liu J, Yang Y
BMC cancer 2024 Jul 19;24(1):868
BMC cancer 2024 Jul 19;24(1):868
CHRDL2 activates the PI3K/AKT pathway to ameliorate glucocorticoid-induced damages to bone microvascular endothelial cells (BMECs).
Huang X, Jie S, Li W, Liu C
Heliyon 2024 Jul 15;10(13):e33867
Heliyon 2024 Jul 15;10(13):e33867
Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditions.
Wu X, Ni Y, Li W, Yang B, Yang X, Zhu Z, Zhang J, Wu X, Shen Q, Liao Z, Yuan L, Chen Y, Du Q, Wang C, Liu P, Miao Y, Li N, Zhang S, Liao M, Hua J
The Journal of biological chemistry 2024 Jan;300(1):105556
The Journal of biological chemistry 2024 Jan;300(1):105556
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
Inhibition of soluble epoxide hydrolase enhances the dentin-pulp complex regeneration mediated by crosstalk between vascular endothelial cells and dental pulp stem cells.
Kong L, Li J, Bai Y, Xu S, Zhang L, Chen W, Gao L, Wang F
Journal of translational medicine 2024 Jan 16;22(1):61
Journal of translational medicine 2024 Jan 16;22(1):61
Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
Wang H, Chen S, Tang Y, Nie K, Gao Y, Wang Z, Su H, Wu F, Gong J, Fang K, Dong H, Hu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155268
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155268
Nicotinamide Riboside Modulates HIF-1 Signaling to Maintain and Enhance Odontoblastic Differentiation in Human Dental Pulp Stem Cells.
Zhan P, Zhang X, Xie Z, Chen L, Huang S, Huang Q, Lin Z, Wang R
Stem cells (Dayton, Ohio) 2024 Feb 8;42(2):116-127
Stem cells (Dayton, Ohio) 2024 Feb 8;42(2):116-127
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Adzraku SY, Cao C, Zhou Q, Yuan K, Hao X, Li Y, Yuan S, Huang Y, Xu K, Qiao J, Ju W, Zeng L
Cell death & disease 2024 Feb 21;15(2):159
Cell death & disease 2024 Feb 21;15(2):159
Restoring sweat gland function in mice using regenerative sweat gland cells derived from chemically reprogrammed human epidermal keratinocytes.
Xiang J, Chen H, Zhang H, Wu L, Li Y, Ji S, Pi W, Cui S, Dong L, Fu X, Sun X
Science bulletin 2024 Dec 30;69(24):3908-3924
Science bulletin 2024 Dec 30;69(24):3908-3924
Isosilybin A exhibits anti-inflammatory properties in rosacea by inhibiting MAPK pathway and M1 macrophage polarization.
Wu CC, Ge JY, Huang XY, Liu XM, Liao Y, Zhang SJ, Wu L, Chen XF, Yu B
International immunopharmacology 2024 Dec 25;143(Pt 1):113323
International immunopharmacology 2024 Dec 25;143(Pt 1):113323
PAI-1 promotes human endometrial stromal decidualization via inhibiting VEGFR2/PI3K/AKT signaling pathway mediated F-actin reorganization.
Zhao H, Liu J, Yin S, Bao H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70233
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70233
F13B regulates angiogenesis and tumor progression in hepatocellular carcinoma via the HIF-1α/VEGF pathway.
Jiang D, Qi Z, Xu ZY, Li YR
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
Biomolecules & biomedicine 2024 Dec 11;25(1):189-209
rTMS Ameliorates time-varying depression and social behaviors in stimulated space complex environment associated with VEGF signaling.
Xu Q, Liang R, Gao J, Fan Y, Dong J, Wang L, Zheng C, Yang J, Ming D
Life sciences in space research 2024 Aug;42:17-26
Life sciences in space research 2024 Aug;42:17-26
Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke.
Zhong L, Fan J, Yan F, Yang Z, Hu Y, Li L, Wang R, Zheng Y, Luo Y, Liu P
CNS neuroscience & therapeutics 2024 Aug;30(8):e70000
CNS neuroscience & therapeutics 2024 Aug;30(8):e70000
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Shang S, Zhuang K, Chen J, Zhang M, Jiang S, Li W
Bioactive materials 2024 Apr;34:298-310
Bioactive materials 2024 Apr;34:298-310
A Nucleic Acid-Based LYTAC Plus Platform to Simultaneously Mediate Disease-Driven Protein Downregulation.
Huang Y, Zhou X, Zhang Y, Xie M, Wang F, Qin J, Ye H, Zhang H, Zhang C, Hong J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
Elevated MPP6 expression correlates with an unfavorable prognosis, angiogenesis and immune evasion in hepatocellular carcinoma.
Cheng Q, Wang W, Liu J, Lv Z, Ji W, Yu J, Zhang W, Yang Y
Frontiers in immunology 2023;14:1173848
Frontiers in immunology 2023;14:1173848
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Zhang Y, Zhao X, Guo C, Zhang Y, Zeng F, Yin Q, Li Z, Shao L, Zhou D, Liu L
Neuroscience bulletin 2023 Sep;39(9):1375-1395
Neuroscience bulletin 2023 Sep;39(9):1375-1395
LncRNA PVT1 promotes strong stemness and endothelial progenitor cell characteristics in renal carcinoma stem cells.
Wang L, Yang G, Guo P, Lv Y, Fu B, Bai Y, Xiong F, Zhao D, Li C, Zhang J, Bai S, Zeng F, Xu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23118
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23118
Effect of Extracellular Ribonucleic Acids on Neurovascularization in Osteoarthritis.
Qin WP, Wan QQ, Yan JF, Han XX, Lu WC, Ma ZY, Ye T, Li YT, Li CJ, Wang C, Tay FR, Niu LN, Jiao K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(26):e2301763
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(26):e2301763
Gap26 inhibited angiogenesis through the β-catenin-VE-cadherin-VEGFR2-Erk signaling pathway.
Xu C, Zhong W, Zhang H, Jiang J, Zhou H
Life sciences 2023 Sep 1;328:121836
Life sciences 2023 Sep 1;328:121836
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
Zhang W, Sun L, Gao H, Wang S
International journal of experimental pathology 2023 Oct;104(5):258-268
International journal of experimental pathology 2023 Oct;104(5):258-268
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
Xiang XH, Wei J, Wang XF, Xu Q, Yu CL, He CL, Long T, Guo MS, Chen X, Zhou XG, Wu JM, Qin DL, Wu AG, Tang Y, Lv HB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway.
Liu L, Gu K, Hua D
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):132-140
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 15;69(11):132-140
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
Huan S, Sun S, Song S, Dai J, Zhu G, Zhong Y, Ji Y, Zheng S, Yin G
International journal of molecular medicine 2023 May;51(5)
International journal of molecular medicine 2023 May;51(5)
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W, Liao J
Genes & diseases 2023 May;10(3):1040-1054
Genes & diseases 2023 May;10(3):1040-1054
BEST1 Positive Monocytes in Circulation: Visualize Intratumoral Crosstalk between Cancer Cells and Monocytes.
Zhang L, Wang Y, Yuan W, An C, Tan Q, Ma J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2205915
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2205915
Low Pi stress enhances the sensitivity of hepatocellular carcinoma to sorafenib.
Bi QC, Deng ZQ, Lv YF, Liu Y, Xie CS, He YQ, Tang Q
Biochemical pharmacology 2023 Jul;213:115593
Biochemical pharmacology 2023 Jul;213:115593
Andrographolide improves the dysfunction of endothelial progenitor cells from angiotensin II-induced hypertensive mice through SIRT1 signaling.
Tu Q, Xu L, Zhang H, Qiu Y, Liu Z, Dong B, Tao J
Biochemical and biophysical research communications 2023 Jan 29;642:11-20
Biochemical and biophysical research communications 2023 Jan 29;642:11-20
SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis.
He Q, Chen Z, Li J, Liu J, Zuo Z, Lin B, Song K, Zhou C, Lai H, Huang Q, Guo X
International journal of molecular sciences 2023 Jan 29;24(3)
International journal of molecular sciences 2023 Jan 29;24(3)
Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis.
Yu L, Liang Y, Zhang M, Yang PC, Hinek A, Mao S
Communications biology 2023 Feb 1;6(1):133
Communications biology 2023 Feb 1;6(1):133
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Nan W, He Y, Shen S, Wu M, Wang S, Zhang Y
Experimental eye research 2023 Dec;237:109680
Experimental eye research 2023 Dec;237:109680
Saponin of Aralia taibaiensis promotes angiogenesis through VEGF/VEGFR2 signaling pathway in cerebral ischemic mice.
Tao X, Liu K, Li W, Zhao S, Liu C, Dai Q, Dong T, Wei P, Duan J, Wang J, Xi M
Journal of ethnopharmacology 2023 Dec 5;317:116771
Journal of ethnopharmacology 2023 Dec 5;317:116771
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
Shen T, Lin R, Hu C, Yu D, Ren C, Li T, Zhu M, Wan Z, Su T, Wu Y, Cai W, Yu J
Journal of neuroinflammation 2023 Dec 21;20(1):308
Journal of neuroinflammation 2023 Dec 21;20(1):308
YAP/STAT3 inhibited CD8(+) T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
Wang C, Shen N, Guo Q, Tan X, He S
Cancer medicine 2023 Aug;12(15):16295-16309
Cancer medicine 2023 Aug;12(15):16295-16309
A novel implant surface modification mode of Fe3O4-containing TiO2 nanorods with sinusoidal electromagnetic field for osteoblastogenesis and angiogenesis.
Ren R, Guo J, Song H, Wei Y, Luo C, Zhang Y, Chen L, Gao B, Fu J, Xiong W
Materials today. Bio 2023 Apr;19:100590
Materials today. Bio 2023 Apr;19:100590
Upregulation of Cell Surface Glycoproteins in Correlation with KSHV LANA in the Kaposi Sarcoma Tumor Microenvironment.
Privatt SR, Ngalamika O, Zhang J, Li Q, Wood C, West JT
Cancers 2023 Apr 6;15(7)
Cancers 2023 Apr 6;15(7)
Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway.
Xia L, Gong M, Zou Y, Wang Z, Wu B, Zhang S, Li L, Jin K, Sun C
Oxidative medicine and cellular longevity 2022;2022:9925919
Oxidative medicine and cellular longevity 2022;2022:9925919
VEGF receptor heterodimers and homodimers are differentially expressed in neuronal and endothelial cell types.
Sarkar J, Luo Y, Zhou Q, Ivakhnitskaia E, Lara D, Katz E, Sun MG, Guaiquil V, Rosenblatt M
PloS one 2022;17(7):e0269818
PloS one 2022;17(7):e0269818
Antidepressant-Like Effect and Mechanism of Ginsenoside Rd on Rodent Models of Depression.
Li Y, Wang ML, Zhang B, Fan XX, Tang Q, Yu X, Li LN, Fan AR, Chang HS, Zhang LZ
Drug design, development and therapy 2022;16:843-861
Drug design, development and therapy 2022;16:843-861
Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.
Zhang J, Yan X, Liu R, Wu S, Liu Q, Li J, Ma J
Cancer management and research 2022;14:1023-1032
Cancer management and research 2022;14:1023-1032
Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation.
Fan XX, Sun WY, Li Y, Tang Q, Li LN, Yu X, Wang SY, Fan AR, Xu XQ, Chang HS
Frontiers in pharmacology 2022;13:968124
Frontiers in pharmacology 2022;13:968124
Mesenchymal Stem Cells-Derived Exosomes Ameliorate Ischemia/Reperfusion Induced Acute Kidney Injury in a Porcine Model.
Huang J, Cao H, Cui B, Ma X, Gao L, Yu C, Shen F, Yang X, Liu N, Qiu A, Cai G, Zhuang S
Frontiers in cell and developmental biology 2022;10:899869
Frontiers in cell and developmental biology 2022;10:899869
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
Liu W, Luo H, Wei Q, Liu J, Wu J, Zhang Y, Chen L, Ren W, Shao L
Bioactive materials 2022 Mar;9:92-104
Bioactive materials 2022 Mar;9:92-104
Construction and a preliminary study of paracrine effect of bone marrow-derived endothelial progenitor cell sheet.
Xue F, Bai Y, Jiang Y, Liu J, Jian K
Cell and tissue banking 2022 Mar;23(1):185-197
Cell and tissue banking 2022 Mar;23(1):185-197
The crescendo pulse frequency of shear stress stimulates the endothelialization of bone marrow mesenchymal stem cells on the luminal surface of decellularized scaffold in the bioreactor.
Jiao Y, Zhang Y, Xiao Y, Xing Y, Cai Z, Wang C, Zhou Z, Feng Z, Gu Y
Bioengineered 2022 Mar;13(3):7925-7938
Bioengineered 2022 Mar;13(3):7925-7938
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma.
Chen C, Guo Y, Huang Q, Wang B, Wang W, Niu J, Lou J, Xu J, Ren T, Huang Y, Guo W
Cancer letters 2022 Jun 28;536:215660
Cancer letters 2022 Jun 28;536:215660
Cellular heterogeneity and immune microenvironment revealed by single-cell transcriptome in venous malformation and cavernous venous malformation.
Li Y, Yang J, Huang Y, Ge S, Song X, Jia R, Wang Y
Journal of molecular and cellular cardiology 2022 Jan;162:130-143
Journal of molecular and cellular cardiology 2022 Jan;162:130-143
Impact of repeated intravenous infusions of umbilical cord-derived versus bone marrow-derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model.
Cheng X, Wang W, Du R, Zhang M, Xie Y, Sun W, Ji J, Sun B, Zhang Y
In vitro cellular & developmental biology. Animal 2022 Dec;58(10):957-969
In vitro cellular & developmental biology. Animal 2022 Dec;58(10):957-969
PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells.
Zhang Y, Zhong Y, Liu W, Zheng F, Zhao Y, Zou L, Liu X
Stem cell research & therapy 2022 Aug 2;13(1):391
Stem cell research & therapy 2022 Aug 2;13(1):391
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis.
Geng B, Zhu Y, Yuan Y, Bai J, Dou Z, Sui A, Luo W
Frontiers in oncology 2021;11:714646
Frontiers in oncology 2021;11:714646
Kaposi's sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene.
Ding Y, Chen W, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Sep;17(9):e1009847
PLoS pathogens 2021 Sep;17(9):e1009847
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Huang W, Xing Y, Zhu L, Zhuo J, Cai M
Experimental cell research 2021 Sep 1;406(1):112633
Experimental cell research 2021 Sep 1;406(1):112633
Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway.
Yang X, Li X, Luo M, Guo Y, Li C, Lv D, Cheng Z, Huang L, Shang FF, Huang B, Shen J, Luo S, Yan J
Journal of ethnopharmacology 2021 Mar 1;267:113642
Journal of ethnopharmacology 2021 Mar 1;267:113642
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Liu A, Lin L, Xu W, Gong Z, Liu Z, Xiao W
Food & function 2021 Jul 5;12(13):5755-5769
Food & function 2021 Jul 5;12(13):5755-5769
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Guan JH, Cao ZY, Guan B, Wei LH, Peng J, Chen YQ, Sferra TJ, Sankararaman S, Zhan ZX, Lin JM
Translational cancer research 2021 Feb;10(2):953-965
Translational cancer research 2021 Feb;10(2):953-965
Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold.
Wang DP, Liu KL, Li XY, Lu GQ, Xue WH, Qian XH, Mohamed O K, Meng FH
European journal of medicinal chemistry 2021 Feb 5;211:113083
European journal of medicinal chemistry 2021 Feb 5;211:113083
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Dec;17(12):e1009600
PLoS pathogens 2021 Dec;17(12):e1009600
Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.
Xu Q, Liu Z, Zhu ZQ, Fan Y, Chen R, Xie XH, Cheng M
Bioengineered 2021 Dec;12(2):12179-12190
Bioengineered 2021 Dec;12(2):12179-12190
MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease.
Xue C, Li X, Ba L, Zhang M, Yang Y, Gao Y, Sun Z, Han Q, Zhao RC
Aging and disease 2021 Aug;12(5):1211-1222
Aging and disease 2021 Aug;12(5):1211-1222
Berberine prevents diabetic retinopathy through inhibiting HIF-1α /VEGF/ NF-κ B pathway in db/db mice.
Yin Z, Tan R, Yuan T, Chen S, Quan Y, Hao Q, Zeng J, Zhao J, Li L
Die Pharmazie 2021 Apr 1;76(4):165-171
Die Pharmazie 2021 Apr 1;76(4):165-171
Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma.
Zhao L, Chen H, Lu L, Zhao C, Malichewe CV, Wang L, Guo X, Zhang X
Life sciences 2021 Apr 1;270:119113
Life sciences 2021 Apr 1;270:119113
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
Chen Q, Yu WY, Zhang HH, Zhang SZ, Fang J, Wu F, Ying HZ, Yu CH
BioMed research international 2020;2020:8954513
BioMed research international 2020;2020:8954513
Identification of Immune-Related Genes Contributing to the Development of Glioblastoma Using Weighted Gene Co-expression Network Analysis.
Kong Y, Feng ZC, Zhang YL, Liu XF, Ma Y, Zhao ZM, Huang B, Chen AJ, Zhang D, Thorsen F, Wang J, Yang N, Li XG
Frontiers in immunology 2020;11:1281
Frontiers in immunology 2020;11:1281
Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy.
Zou J, Liu KC, Wang WP, Xu Y
Life sciences 2020 Sep 1;256:117888
Life sciences 2020 Sep 1;256:117888
BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway.
Li Y, Shang Q, Li P, Yang Z, Yang J, Shi J, Ge S, Wang Y, Fan X, Jia R
Journal of molecular and cellular cardiology 2020 Oct;147:92-107
Journal of molecular and cellular cardiology 2020 Oct;147:92-107
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Zoledronate Inhibits Osteoclast Differentiation via Suppressing Vascular Endothelial Growth Factor Receptor 2 Expression.
Nakagawa T, Ohta K, Uetsuki R, Kato H, Naruse T, Murodumi H, Yokoyama S, Sakuma M, Ono S, Takechi M
Biochemical genetics 2020 Jun;58(3):473-489
Biochemical genetics 2020 Jun;58(3):473-489
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Wang M, Jiang X
Anti-cancer drugs 2020 Jun;31(5):492-499
Anti-cancer drugs 2020 Jun;31(5):492-499
Protective Effects of Combination of Radix Astragali and Radix Salviae Miltiorrhizae on Kidney of Spontaneously Hypertensive Rats and Renal Intrinsic Cells.
Li W, Jiang YH, Wang Y, Zhao M, Hou GJ, Hu HZ, Zhou L
Chinese journal of integrative medicine 2020 Jan;26(1):46-53
Chinese journal of integrative medicine 2020 Jan;26(1):46-53
Aerobic and resistance training enhances endothelial progenitor cell function via upregulation of caveolin-1 in mice with type 2 diabetes.
Zhai L, Liu Y, Zhao W, Chen Q, Guo T, Wei W, Luo Z, Huang Y, Ma C, Huang F, Dai X
Stem cell research & therapy 2020 Jan 3;11(1):10
Stem cell research & therapy 2020 Jan 3;11(1):10
Brivanib, a multitargeted small-molecule tyrosine kinase inhibitor, suppresses laser-induced CNV in a mouse model of neovascular AMD.
Li L, Zhu M, Wu W, Qin B, Gu J, Tu Y, Chen J, Liu D, Shi Y, Liu X, Sang A, Ding D
Journal of cellular physiology 2020 Feb;235(2):1259-1273
Journal of cellular physiology 2020 Feb;235(2):1259-1273
Anti-angiogenic activity of ShengMaBieJia decoction in vitro and in acute myeloid leukaemia tumour-bearing mouse models.
Wang M, Ma B, Dai X, Zhang H, Dai H, Wang J, Liu L, Sun X
Pharmaceutical biology 2020 Dec;58(1):454-464
Pharmaceutical biology 2020 Dec;58(1):454-464
MiR-17-5p promotes the endothelialization of endothelial progenitor cells to facilitate the vascular repair of aneurysm by regulating PTEN-mediated PI3K/AKT/VEGFA pathway.
Tian Y, Li X, Bai C, Yang Z, Zhang L, Luo J
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3608-3621
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3608-3621
Qingjie Fuzheng Granules regulates cancer cell proliferation, apoptosis and tumor angiogenesis in colorectal cancer xenograft mice via Sonic Hedgehog pathway.
Zhu XQ, Yang H, Lin MH, Shang HX, Peng J, Chen WJ, Chen XZ, Lin JM
Journal of gastrointestinal oncology 2020 Dec;11(6):1123-1134
Journal of gastrointestinal oncology 2020 Dec;11(6):1123-1134
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Su X, Ma X, Xie X, Wu H, Wang L, Feng Y, Yu Z, Liu C, Qi J, Zhu Q
Cell death discovery 2020 Dec 8;6(1):140
Cell death discovery 2020 Dec 8;6(1):140
Effect of Aerobic and Resistance Training on Endothelial Progenitor Cells in Mice with Type 2 Diabetes.
Dai X, Zhai L, Su Q, Luo B, Wei C, Liu Y, Huang Y, Ma C, Ying Y
Cellular reprogramming 2020 Aug;22(4):189-197
Cellular reprogramming 2020 Aug;22(4):189-197
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
Jie M, Ma H, Zhou L, Wu J, Li M, Liu X, Wang D
International journal of molecular sciences 2020 Aug 16;21(16)
International journal of molecular sciences 2020 Aug 16;21(16)
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Zhang S, Zhang R, Xu R, Shang J, He H, Yang Q
Gene 2020 Apr 5;733:144383
Gene 2020 Apr 5;733:144383
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
Liu R, Yu R, Cui Y, Fan M, Wang B, Zhang Y
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway.
Huang HT, Liu ZC, Wu KQ, Gu SR, Lu TC, Zhong CJ, Zhou YX
Annals of translational medicine 2019 Oct;7(20):563
Annals of translational medicine 2019 Oct;7(20):563
PlGF signaling and macrophage repolarization contribute to the anti-neoplastic effect of metformin.
Ma Q, Gu JT, Wang B, Feng J, Yang L, Kang XW, Duan P, Sun X, Liu PJ, Wang JC
European journal of pharmacology 2019 Nov 15;863:172696
European journal of pharmacology 2019 Nov 15;863:172696
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
Exosomes derived from acute myeloid leukemia cells promote chemoresistance by enhancing glycolysis-mediated vascular remodeling.
Wang B, Wang X, Hou D, Huang Q, Zhan W, Chen C, Liu J, You R, Xie J, Chen P, Huang H
Journal of cellular physiology 2019 Jul;234(7):10602-10614
Journal of cellular physiology 2019 Jul;234(7):10602-10614
VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.
Lian L, Li XL, Xu MD, Li XM, Wu MY, Zhang Y, Tao M, Li W, Shen XM, Zhou C, Jiang M
BMC cancer 2019 Feb 28;19(1):183
BMC cancer 2019 Feb 28;19(1):183
Myricetin Inhibits Breast Tumor Growth and Angiogenesis by Regulating VEGF/VEGFR2 and p38MAPK Signaling Pathways.
Zhou Z, Mao W, Li Y, Qi C, He Y
Anatomical record (Hoboken, N.J. : 2007) 2019 Dec;302(12):2186-2192
Anatomical record (Hoboken, N.J. : 2007) 2019 Dec;302(12):2186-2192
Human Colorectal Cancer Infrastructure Constructed by the Glycocalyx.
Tachi M, Okada H, Matsuhashi N, Takemura G, Suzuki K, Fukuda H, Niwa A, Tanaka T, Mori H, Hara A, Yoshida K, Ogura S, Tomita H
Journal of clinical medicine 2019 Aug 22;8(9)
Journal of clinical medicine 2019 Aug 22;8(9)
Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R.
Han Y, Ren J, Bai Y, Pei X, Han Y
The international journal of biochemistry & cell biology 2019 Apr;109:59-68
The international journal of biochemistry & cell biology 2019 Apr;109:59-68
Resveratrol Promotes Nerve Regeneration via Activation of p300 Acetyltransferase-Mediated VEGF Signaling in a Rat Model of Sciatic Nerve Crush Injury.
Ding Z, Cao J, Shen Y, Zou Y, Yang X, Zhou W, Guo Q, Huang C
Frontiers in neuroscience 2018;12:341
Frontiers in neuroscience 2018;12:341
SK-Hep1: not hepatocellular carcinoma cells but a cell model for liver sinusoidal endothelial cells.
Tai Y, Gao JH, Zhao C, Tong H, Zheng SP, Huang ZY, Liu R, Tang CW, Li J
International journal of clinical and experimental pathology 2018;11(5):2931-2938
International journal of clinical and experimental pathology 2018;11(5):2931-2938
Effects of l-arginine on endometrial microvessel density in nutrient-restricted Hu sheep.
Gao XX, Li XH, Zhang QF, Zhu M, Guo YX, Deng KP, Zhang GM, Wang F
Theriogenology 2018 Oct 1;119:252-258
Theriogenology 2018 Oct 1;119:252-258
miR‑1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor.
Zhu D, Sun Y, Zhang D, Dong M, Jiang G, Zhang X, Zhou J
Oncology reports 2018 Aug;40(2):589-598
Oncology reports 2018 Aug;40(2):589-598
Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.
LeBlanc ME, Wang W, Chen X, Caberoy NB, Guo F, Shen C, Ji Y, Tian H, Wang H, Chen R, Li W
The Journal of experimental medicine 2017 Apr 3;214(4):1029-1047
The Journal of experimental medicine 2017 Apr 3;214(4):1029-1047
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation.
Zheng X, Zhang Y, Zhang L, Xu W, Ma W, Sun R, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:212-220
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:212-220
Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.
Ahmed RS, Liu G, Renzetti A, Farshi P, Yang H, Soave C, Saed G, El-Ghoneimy AA, El-Banna HA, Foldes R, Chan TH, Dou QP
Journal of cellular biochemistry 2016 Oct;117(10):2357-69
Journal of cellular biochemistry 2016 Oct;117(10):2357-69
Eupolyphaga sinensis Walker demonstrates angiogenic activity and inhibits A549 cell growth by targeting the KDR signaling pathway.
Dai B, Qi J, Liu R, Zhang Y
Molecular medicine reports 2014 Sep;10(3):1590-6
Molecular medicine reports 2014 Sep;10(3):1590-6
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