NBP2-34657AF488

antibody from Novus Biologicals

Targeting: KDR CD309, FLK1, VEGFR, VEGFR2

ELISA (Data presented on provider website)

Antibody Data

Product number

NBP2-34657AF488

Provider

Novus Biologicals

Product name

Mouse Monoclonal VEGFR2/KDR/Flk-1 Antibody

Antibody type

Monoclonal

Description

Protein A purified. CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.