Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB357C-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human VEGFR2/KDR/Flk-1 PerCP-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human VEGF R2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGF R1, rhVEGF R3 or recombinant mouse VEGF R2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P35968
- Isotype
- IgG
- Antibody clone number
- 89106
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
Circulating progenitor and angiogenic cell frequencies are abnormally static over pregnancy in women with preconception diabetes: A pilot study.
Endothelial progenitor cells are differentially impaired in ANCA-associated vasculitis compared to healthy controls.
Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma.
Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery.
Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z
Redox biology 2019 Jun;24:101192
Redox biology 2019 Jun;24:101192
Circulating progenitor and angiogenic cell frequencies are abnormally static over pregnancy in women with preconception diabetes: A pilot study.
Lima PD, Chen Z, Tayab A, Murphy MS, Pudwell J, Smith GN, Croy BA
PloS one 2017;12(3):e0172988
PloS one 2017;12(3):e0172988
Endothelial progenitor cells are differentially impaired in ANCA-associated vasculitis compared to healthy controls.
Wilde B, Mertens A, Arends SJ, Rouhl RP, Bijleveld R, Huitema J, Timmermans SA, Damoiseaux J, Witzke O, Duijvestijn AM, van Paassen P, van Oostenbrugge RJ, Cohen Tervaert JW
Arthritis research & therapy 2016 Jun 23;18:147
Arthritis research & therapy 2016 Jun 23;18:147
Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma.
Chen L, Liu H, Liu J, Zhu Y, Xu L, He H, Zhang H, Wang S, Wu Q, Liu W, Liu Y, Pan D, Ren S, Xu J, Gu J
PloS one 2013;8(3):e58413
PloS one 2013;8(3):e58413
Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery.
Knight DR Jr, Smith AH, Schroeder RL, Huang C, Beebe DA, Sokolowski SA, Wang M
Journal of translational medicine 2013 Apr 22;11:101
Journal of translational medicine 2013 Apr 22;11:101
Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
Cheung C, Bernardo AS, Trotter MW, Pedersen RA, Sinha S
Nature biotechnology 2012 Jan 15;30(2):165-73
Nature biotechnology 2012 Jan 15;30(2):165-73
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of VEGF R2/KDR/Flk-1 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R2/KDR/Flk-1 PerCP-conjugated Mono-clonal Antibody (Catalog # FAB357C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.