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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN362033 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362033, RRID:AB_10953572
- Product name
- anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr1175) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr1175 (K-D-Y (p) -I-V) derived from Human VEGFR2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr1175
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.
Lamalice L, Houle F, Jourdan G, Huot J
Oncogene 2004 Jan 15;23(2):434-45
Oncogene 2004 Jan 15;23(2):434-45
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.
Takahashi T, Yamaguchi S, Chida K, Shibuya M
The EMBO journal 2001 Jun 1;20(11):2768-78
The EMBO journal 2001 Jun 1;20(11):2768-78
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