338909

antibody from BioLegend
Targeting: KDR CD309, FLK1, VEGFR, VEGFR2
Provider product page for 338909
Flow cytometry

Antibody data

Product number
338909 - Provider product page
Provider
BioLegend
Product name
Alexa Fluor® 647 anti-human CD309 (VEGFR2, Flk-1) [HKDR-1]
Antibody type
Monoclonal
Antigen
CD309 (VEGFR2)
Description
VEGF-R2, known as KDR, CD309, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
KDR protein structure - 338909 shown in red.