PAB12134

antibody from Abnova Corporation

Targeting: KDR CD309, FLK1, VEGFR, VEGFR2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12134

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12134, RRID:AB_10552512

Product name

Kdr polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of Kdr.

Storage

Store at 4°C. Do not freeze.

References

Submitted references

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

Hu-Lowe DD, Zou HY, Grazzini ML, Hallin ME, Wickman GR, Amundson K, Chen JH, Rewolinski DA, Yamazaki S, Wu EY, McTigue MA, Murray BW, Kania RS, O'Connor P, Shalinsky DR, Bender SL
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Nov 15;14(22):7272-83

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A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1.

Takahashi H, Hattori S, Iwamatsu A, Takizawa H, Shibuya M
The Journal of biological chemistry 2004 Oct 29;279(44):46304-14

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Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells.

Rahimi N, Dayanir V, Lashkari K
The Journal of biological chemistry 2000 Jun 2;275(22):16986-92

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of Kdr in CSF-IR/VEGFR2 chimera transfected lysate using Kdr polyclonal antibody (Cat # PAB12134). ECL 10 second exposure.