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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN1355904 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr1059) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr1059 (P-D-Y (p) -V-R) derived from Human VEGFR2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pTyr1059
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively.
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization.
Zeng H, Sanyal S, Mukhopadhyay D
The Journal of biological chemistry 2001 Aug 31;276(35):32714-9
The Journal of biological chemistry 2001 Aug 31;276(35):32714-9
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization.
Dougher M, Terman BI
Oncogene 1999 Feb 25;18(8):1619-27
Oncogene 1999 Feb 25;18(8):1619-27
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