CABT-B1602

antibody from Creative Diagnostics
Targeting: IDH1
Provider product page for CABT-B1602
Western blot

Antibody data

Product number
CABT-B1602 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-IDH1 polyclonal antibody
Antibody type
Polyclonal
Description
Isocitrate dehydrogenase 1 (IDH1) is a 46 kDa NADP-dependent enzyme, which catalyzes the decarboxylation of isocitrate into Ï«-ketoglutarate. IDH1 may also play a role in the prevention of oxidative damage, and the shuttling of proteins to peroxisomes. It is widely reported that mutations in IDH1 result in multiple forms of gliomas. The Arginine to Serine substitution at amino acid 132 is seen in gliomas, abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 _g
Concentration
Please refer to lot specific datasheet.
Storage
Stable for 1 year at 2-8°C from date of receipt.
IDH1 protein structure - CABT-B1602 shown in red.