13361-1-AP
antibody from Proteintech Group
Targeting: PIKFYVE
FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13361-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13361-1-AP, RRID:AB_10638310
- Product name
- PIP5K3 antibody
- Antibody type
- Polyclonal
- Description
- PIP5K3 antibody (Cat. #13361-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry.
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
TRIM68, PIKFYVE, and DYNLL2: The Possible Novel Autophagy- and Immunity-Associated Gene Biomarkers for Osteosarcoma Prognosis.
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
miR32-5p promoted vascular smooth muscle cell calcification by upregulating TNFα in the microenvironment.
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
Inhibition of c-Rel DNA binding is critical for the anti-inflammatory effects of novel PIKfyve inhibitor.
Su BQ, Yang GY, Wang J, Ming SL, Chu BB
PLoS pathogens 2024 Jan;20(1):e1011956
PLoS pathogens 2024 Jan;20(1):e1011956
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, Perez J, Couto A, Lai J, Li Y, Alworth SV, Hendricks E, Wang Y, Zlokovic BV, Dickman DK, Parker JA, Zarnescu DC, Gao FB, Ichida JK
Cell 2023 Feb 16;186(4):786-802.e28
Cell 2023 Feb 16;186(4):786-802.e28
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP, Luo G, Rivero-Rios P, Steinfeld N, Tronchere H, Singla A, Burstein E, Billadeau DD, Sutton MA, Weisman LS
eLife 2022 Jan 18;11
eLife 2022 Jan 18;11
TRIM68, PIKFYVE, and DYNLL2: The Possible Novel Autophagy- and Immunity-Associated Gene Biomarkers for Osteosarcoma Prognosis.
Jiang J, Liu D, Xu G, Liang T, Yu C, Liao S, Chen L, Huang S, Sun X, Yi M, Zhang Z, Lu Z, Wang Z, Chen J, Chen T, Li H, Yao Y, Chen W, Guo H, Liu C, Zhan X
Frontiers in oncology 2021;11:643104
Frontiers in oncology 2021;11:643104
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D
Molecular cell 2021 Jul 1;81(13):2705-2721.e8
Molecular cell 2021 Jul 1;81(13):2705-2721.e8
miR32-5p promoted vascular smooth muscle cell calcification by upregulating TNFα in the microenvironment.
Cao J, Chen L, Zhong X, Shen Y, Gao Y, Chen Q, Zu X, Liu J
BMC immunology 2020 Jan 17;21(1):3
BMC immunology 2020 Jan 17;21(1):3
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
Fernandez-Mosquera L, Yambire KF, Couto R, Pereyra L, Pabis K, Ponsford AH, Diogo CV, Stagi M, Milosevic I, Raimundo N
Autophagy 2019 Sep;15(9):1572-1591
Autophagy 2019 Sep;15(9):1572-1591
Inhibition of c-Rel DNA binding is critical for the anti-inflammatory effects of novel PIKfyve inhibitor.
Terajima M, Kaneko-Kobayashi Y, Nakamura N, Yuri M, Hiramoto M, Naitou M, Hattori K, Yokota H, Mizuhara H, Higashi Y
European journal of pharmacology 2016 Jun 5;780:93-105
European journal of pharmacology 2016 Jun 5;780:93-105
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PIP5K3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PIP5K3. This antibody recognizes human, mouse, rat antigen. The PIP5K3 antibody has been validated for the following applications: ELISA, WB analysis.