ABIN358406

antibody from antibodies-online

Targeting: EIF4E EIF4E1, EIF4EL1, EIF4F

No application information provided.

Antibody Data

Product number

ABIN358406

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibody

Antibody type

Polyclonal

Description

Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

pSer209

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins.

Whalen SG, Gingras AC, Amankwa L, Mader S, Branton PE, Aebersold R, Sonenberg N
The Journal of biological chemistry 1996 May 17;271(20):11831-7

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Assignment of two of the translation initiation factor-4E (EIF4EL1 and EIF4EL2) genes to human chromosomes 4 and 20.

Pelletier J, Brook JD, Housman DE
Genomics 1991 Aug;10(4):1079-82

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Chromosomal assignment of one of the mammalian translation initiation factor eIF-4E genes.

Dorfman J, Lazaris-Karatzas A, Malo D, Sonenberg N, Gros P
Genomics 1991 Apr;9(4):785-8

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Phosphorylation site of eukaryotic initiation factor 4E.

Rychlik W, Russ MA, Rhoads RE
The Journal of biological chemistry 1987 Aug 5;262(22):10434-7