Tissue expression
Cell line expression
Protein structure
EIF4E
Eukaryotic translation initiation factor 4EEIF4E1, EIF4EL1, EIF4F
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Top validated antibodies |
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| Proteintech Group | 21 references | Polyclonal |
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| Invitrogen Antibodies | 4 references | Polyclonal |
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| antibodies-online | 2 references | Monoclonal |
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| Acris Antibodies GmbH | Monoclonal |
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| GeneTex | Monoclonal |
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