Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB1263P - Provider product page
- Provider
- R&D Systems
- Product name
- Human PDGF R beta PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human PDGF R beta in Western blots. Specificity has been confirmed in binding studies using several different cell lines (1, 2) and by its ability to immunoprecipitate PDGF R beta-subunit complexed with 125I-PDGF-BB (3). It does not recognize the PDGF R alpha-subunit. Detects the PDGF R beta-subunit of human and primate species (monkey and baboon) but not the rat or mouse receptors. Its ability to bind to receptors from other species has not been tested.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- PR7212
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle.
Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.
Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes.
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.
Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis.
Xu S, Chan RWS, Ng EHY, Yeung WSB
Experimental cell research 2017 Jan 1;350(1):184-189
Experimental cell research 2017 Jan 1;350(1):184-189
Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.
To C, Farnsworth RH, Vail ME, Chheang C, Gargett CE, Murone C, Llerena C, Major AT, Scott AM, Janes PW, Lackmann M
PloS one 2014;9(11):e112106
PloS one 2014;9(11):e112106
Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
Norton KA, Han Z, Popel AS, Pandey NB
OncoTargets and therapy 2014;7:1571-82
OncoTargets and therapy 2014;7:1571-82
Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes.
Guijarro-Muñoz I, Compte M, Álvarez-Cienfuegos A, Álvarez-Vallina L, Sanz L
The Journal of biological chemistry 2014 Jan 24;289(4):2457-68
The Journal of biological chemistry 2014 Jan 24;289(4):2457-68
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.
Frassanito MA, Rao L, Moschetta M, Ria R, Di Marzo L, De Luisi A, Racanelli V, Catacchio I, Berardi S, Basile A, Menu E, Ruggieri S, Nico B, Ribatti D, Fumarulo R, Dammacco F, Vanderkerken K, Vacca A
Leukemia 2014 Apr;28(4):904-16
Leukemia 2014 Apr;28(4):904-16
Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.
Albert R, Veréb Z, Csomós K, Moe MC, Johnsen EO, Olstad OK, Nicolaissen B, Rajnavölgyi E, Fésüs L, Berta A, Petrovski G
PloS one 2012;7(10):e47187
PloS one 2012;7(10):e47187
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis.
Guijarro-Muñoz I, Cuesta AM, Alvarez-Cienfuegos A, Geng JG, Alvarez-Vallina L, Sanz L
Experimental cell research 2012 Feb 15;318(4):371-8
Experimental cell research 2012 Feb 15;318(4):371-8
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of PDGF R beta in MG-63 Human Cell Line by Flow Cytometry. MG-63 human osteosarcoma cell line was stained with Mouse Anti-Human PDGF R beta PE-conjugated Monoclonal Antibody (Catalog # FAB1263P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.