PDGFRB

gene product
CD140b, JTK12, PDGFR, PDGFR1
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
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1434 antibodies from 43 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
125 antibodies
R&D Systems
21 antibodies
Invitrogen Antibodies
36 antibodies
Biorbyt
50 antibodies
Abnova Corporation
29 antibodies
GeneTex
33 antibodies
OriGene
78 antibodies
Abgent
12 antibodies
NSJ Bioreagents
6 antibodies
NovoPro Bioscience Inc.
17 antibodies
antibodies-online
289 antibodies
Aviva Systems Biology
16 antibodies
Cell Signaling Technology, Inc
13 antibodies
LifeSpan BioSciences, Inc.
194 antibodies