CABT-BL5476

antibody from Creative Diagnostics

Targeting: PYHIN1 IFIX, MGC23885

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL5476

Provider

Creative Diagnostics

Product name

Anti-PYHIN1 (aa 38-87) polyclonal antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 _g

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.