PYHIN1

gene product
IFIX, MGC23885
The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
117 antibodies from 18 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
45 antibodies
Abgent
1 antibody
Invitrogen Antibodies
2 antibodies
Aviva Systems Biology
3 antibodies
LifeSpan BioSciences, Inc.
25 antibodies
Novus Biologicals
3 antibodies
Atlas Antibodies
1 antibody
ProSci
1 antibody
Cusabio Biotech Co., Ltd
4 antibodies
OriGene
2 antibodies
Biorbyt
4 antibodies
MyBioSource
1 antibody
United States Biological
13 antibodies
Leading Biology
1 antibody
Creative Diagnostics
2 antibodies
Abbexa
5 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Abnova Corporation
1 antibody