PA1-86644

antibody from Invitrogen Antibodies

Targeting: ERBB3 HER3, LCCS2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

PA1-86644

Provider

Invitrogen Antibodies

Product name

Anti-ErbB3 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Predicted to react with dog, mouse and rat based on sequence homology. In Western blot, this antibody detects a band at ~150 kDa in Jurkat cell lysates. A minimum incubation time of 1 hour is recommended with this antibody. Goat anti Human Erb3 antibody recognizes the human Receptor tyrosine-protein kinase erbB-3, also known as ErbB3, Proto-oncogene-like protein c-ErbB-3 or Tyrosine kinase-type cell surface receptor HER3.

Reactivity

Human

Host

Goat

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/mL

Storage

4°C or -20°C if preferred

References

Submitted references

Dasatinib inhibition of cSRC prevents the migration and metastasis of canine mammary cancer cells with enhanced Wnt and HER signalling.

Timmermans-Sprang EPM, Mestemaker HM, Steenlage RR, Mol JA
Veterinary and comparative oncology 2019 Sep;17(3):413-426

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High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression.

Timmermans-Sprang EP, Gracanin A, Mol JA
BMC cancer 2015 Jul 25;15:545