MAB5860
antibody from Abnova Corporation
Targeting: BCL2L1
Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MAB5860 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB5860, RRID:AB_10549906
- Product name
- BCL2L1 monoclonal antibody, clone 7B2.5 (Biotin)
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant BCL2L1.
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- 7B2.5
- Storage
- Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Submitted references Bax-independent inhibition of apoptosis by Bcl-XL.
Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.
Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak.
Cheng EH, Levine B, Boise LH, Thompson CB, Hardwick JM
Nature 1996 Feb 8;379(6565):554-6
Nature 1996 Feb 8;379(6565):554-6
Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.
Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H, Tsujimoto Y
Nature 1995 Apr 27;374(6525):811-3
Nature 1995 Apr 27;374(6525):811-3
Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak.
Kiefer MC, Brauer MJ, Powers VC, Wu JJ, Umansky SR, Tomei LD, Barr PJ
Nature 1995 Apr 20;374(6524):736-9
Nature 1995 Apr 20;374(6524):736-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Murine FL5 cells (FL5-NEO) and FL5 cells transfected with Bcl-xL expression plasmid (FL5-BCL-XL) were fixed with buffered paraformaldehyde and then permeabilized with saponin. The cells were incubated with BCL2L1 monoclonal antibody, clone 7B2.5 followed by phycoerythrin-conjugated goat anti-mouse IgG, and then were analyzed by flow cytometry.
- Validation comment
- Flow Cytometry