BCL2L1

gene product
Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
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1868 antibodies from 47 providers.

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Novus Biologicals
202 antibodies
GeneTex
16 antibodies
Abnova Corporation
28 antibodies
Cell Signaling Technology, Inc
7 antibodies
Invitrogen Antibodies
22 antibodies
NovoPro Bioscience Inc.
14 antibodies
OriGene
64 antibodies
Proteintech Group
2 antibodies
antibodies-online
744 antibodies
Abgent
13 antibodies
Boster Biological Technology
7 antibodies
NSJ Bioreagents
7 antibodies
R&D Systems
2 antibodies
Aviva Systems Biology
14 antibodies
Biorbyt
73 antibodies
LifeSpan BioSciences, Inc.
255 antibodies
Affinity Biosciences
5 antibodies
Acris Antibodies GmbH
50 antibodies
Signalway Antibody LLC
3 antibodies
Bioworld Technology, Inc
5 antibodies
St John's Laboratory
9 antibodies
Enzo Life Sciences
3 antibodies
FabGennix
3 antibodies
Atlas Antibodies
1 antibody
RabMAbs
3 antibodies
Spring Bioscience
12 antibodies
Abbkine Scientific Co.Ltd.
7 antibodies
Creative Diagnostics
19 antibodies
United States Biological
120 antibodies
BioLegend
2 antibodies
Creative Biolabs
25 antibodies
EMD Millipore
4 antibodies
MyBioSource
24 antibodies
ProSci
5 antibodies
RayBiotech, Inc.
3 antibodies
Rockland Immunochemicals, Inc.
1 antibody
GenWay
18 antibodies
Sino Biological Inc.
2 antibodies
Abiocode, Inc.
1 antibody
Bethyl Laboratories
1 antibody
Abbexa
3 antibodies
Sigma-Aldrich
7 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Exalpha Biologicals, Inc.
2 antibodies
Active Motif
1 antibody