BCL2L1

gene product
Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
22 antibodies
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131 antibodies
GeneTex
15 antibodies
Abnova Corporation
28 antibodies
Cell Signaling Technology, Inc
6 antibodies
NovoPro Bioscience Inc.
14 antibodies
Proteintech Group
2 antibodies
OriGene
69 antibodies
R&D Systems
2 antibodies
Abgent
13 antibodies
antibodies-online
334 antibodies
Boster Biological Technology
7 antibodies
NSJ Bioreagents
7 antibodies
Aviva Systems Biology
14 antibodies
Biorbyt
53 antibodies
LifeSpan BioSciences, Inc.
203 antibodies