ALX-804-660-C100
antibody from Enzo Life Sciences
Targeting: BCL2L1
Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ALX-804-660-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-660-C100, RRID:AB_2050814
- Product name
- Bcl-XL monoclonal antibody (1C2)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 1C2
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM
The Journal of cell biology 2007 Apr 23;177(2):277-87
The Journal of cell biology 2007 Apr 23;177(2):277-87
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC
Genes & development 2005 Jun 1;19(11):1294-305
Genes & development 2005 Jun 1;19(11):1294-305
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