AP21590PU-S

antibody from Acris Antibodies GmbH

Targeting: BCL2L1 Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AP21590PU-S

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP21590PU-S, RRID:AB_10756586

Product name

anti Bcl-2-like 1

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to amino acids 61-79 (DSPAVNGATAHSSSLDARE) of human Bcl-XL

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

50 µl

Immunohistochemistry

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Formalin-fixed paraffin-embedded section of dog ischemic brain cortex stained for Bcl-X expression using AP21590PU-S at 1/2000. At 2 hr post ischemia, Bcl-X staining was seen in the dying neurons that had morphological features of apoptosis (arrows). In contrast, mophologically normal appearing neurons lacked Bcl-X staining (arrowheads). Hematoxylin-eosin counterstain.

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Formalin-fixed paraffin- embedded human tissue sections stained for Bcl-X expression using AP21590PU-S at 1/2000. A. Cortex from the brain of an Alzheimer's disease patient. The degenerating neurons are positive for BclX expression, the intact neurons are not. B. Normal bone marrow. The cells positive for Bcl-X expression appear to be of erythropoetic lineage. Hematoxylin-eosin counterstain.